A internet e a prática da leitura: o uso da rede por acadêmicos do sexto período do curso superior em Tecnologia em Alimentos

Pós-graduação em Educação - FFC

Avaliação do pH na amostra isolada e na urina de 24h de pacientes litiásicos em uso de citrato de potássio

Pós-graduação em Bases Gerais da Cirurgia - FMB

Concentração de flúor e cálcio no fluido do biofilme associada ao uso de dentifrícios fluoretados suplementados com trimetafosfato de sódio ou glicerofosfato de cálcio, sob desafio cariogênico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudos de permeação e liberação de peptídeos antimicrobianos estruturalmente derivados da toxina CCDB

O uso de peptídeos sintéticos para o desenvolvimento de novas drogas é uma estratégia promissora no campo da biotecnologia. Peptídeos derivados de toxinas bacterianas intracelulares, produzidas por sistemas de morte pós-segregacional (PKS) tais como CcdB e ParE são exemplos dessa estratégia. Porém, moléculas com estrutura peptídica derivadas de toxinas bacterianas apresentam sérios problemas na aplicação terapêutica por apresentarem baixa solubilidade e difícil permeabilidade em membranas bacterianas. O objetivo desse estudo consistiu no desenvolvimento e aprimoramento de sistemas nanoestruturados (lipossomas) que permita a imobilização de análogos peptídicos da toxina CcdB e sua consequente translocação no citosol bacteriano, permitindo que os mesmos atinjam seus alvos celulares, enzimas DNA girase e Topoisomerase IV. Lipossomas do tipo SUV (small unilamellar vesicles), foram preparados pela técnica de extrusão-evaporação variando-se suas formulações. Desta forma, pretendeu-se avaliar a eficiência de encapsulação dos peptídeos através de técnicas de cromatografia líquida de alta eficiência (CLAE) e espectroscopia de UV-Vis e fluorescência. Após testes de eficiência de encapsulação, os lipossomas contendo os análogos peptídicos encapsulados, foram submetidos a ensaio de inibição de crescimento em meio líquido para duas espécies bacterianas: Staphylococcus aureus e Escherichia coli. Resultados demonstraram que a utilização de sistemas nanoestruturados é de grande importância para viabilizar a aplicação desta classe de biomoléculas em estudos terapêuticos, permitindo assim, que tais peptídeos possam ser utilizados como antibióticos promissores, se associados a sistemas de transporte e liberação controlada de moléculas peptídicas.

Estudos sobre a aplicação do pentacloreto de nióbio na síntese de derivados de 4-aril-3,4-di- hidrocumarinas

Coumarin is a natural active compound that can be found in many plants. The coumarins have many properties such as bronchodilator, anti-inflammatory, antioxidant, anticoagulant, antibiotics, immunomodulatory, antimicrobial and antiviral, thus, they are widely used in medical applications. More recently the coumarin derivatives have attracted the interest of many research groups in the field of new materials, for example the possibility of their use as sensitizers in dye-sensitized solar cells (DSSC) and lasers. The MCRs are defined as a process in which three or more reactants are combined in the same reaction pot, resulting in products with good structural complexity a single step, in addition to economy of atoms and selectivity and is a very important feature in modern synthetic methodology. In this work we investigated the use of niobium pentachloride as catalyst of the multicomponent reactions between phenolic derivatives, various aromatic aldehydes and β-diester derivatives in the synthesis of 4-aryl-3,4-dihydrocoumarin derivatives. The reactions were carried out at room temperature, under inert atmosphere (N2), using dichloromethane anhydrous (CH2 Cl2) as solvent, with a reaction time of most 120 hours. The products were isolated by column chromatography on silica gel and submitted to spectrometric and spectroscopic analysis. The results show that NbCl5 is an excellent agent for promoting the synthesis of 4-aryl-3,4-dihydrocoumarin derivatives through multicomponent reactions, obtaining yields varying from 45 to 95%

Viabilidade técnica e econômica do uso da energia solar térmica em condomínios horizontais com habitações populares

Pós-graduação em Engenharia Mecânica - FEG

Avaliação do uso de técnicas digitais para caracterização de área degradada por empréstimo de solo: máxima verossimilhança x modelo linear de mistura espectral

Pós-graduação em Engenharia Civil - FEIS

Síntese e estudos de sistemas de bioencapsulação associados a peptídeos antimicrobianos miméticos da toxina natural CcdB

Pós-graduação em Biotecnologia - IQ

Analise técnica, econômica e ecológica da incorporação de sistemas de gaseificação de bagaço de cana-de-açúcar no setor sucroalcooleiro: uso de ciclos combinados para o aumento da oferta de eletricidade

Pós-graduação em Engenharia Mecânica - FEG

Limites e contribuições do uso da EME para pesquisas de cunho qualitativo na aquisição do PB

The main objective of this paper is to answer the following question: how can we draw a parallel, during the analysis of the data, between children who are at different moments in the language acquisition process or who belong to different populations (children that are monolingual, bilingual, with language disorders, etc.)? In order to answer this question, we are discussing the advantages and limitations of adopting a measure like MLU, from English Mean Length of Utterance, or EME as it was named in Brazil, proposed by Roger Brown (1973). We intend to verify the effective contribution of these measures to the studies in the area and propose an adaptation in the studies that use a qualitative approach. Firstly, we recall the study of the criteria proposed by Brown (1973), Scliar-Cabral (1976), Parker & Brorson (2005), Parisse & Le Normand (2006), and Araújo (2007), and by scholars of Brazilian Portuguese morphology, like Câmara Jr (2009), Monteiro (2002), and Kehdi (1990), among others. Secondly, from a dialogic-discursive point of view (BAKHTIN, 2006; BAKHTIN/ VOLOSHINOV, 1992, 1981), we provide as an example the research on the plural in the language acquisition process (HILÁRIO, 2010, 2011b, 2012). The reflections made indicate that EME may be a useful measure for the researches on language acquisition. Nevertheless, adaptations should be done and its inherent problems should be taken into account, especially if other factors are considered – like the age, the number of types/occurrences, the maximum limit of items per utterance etc. – although it is not the only parameter of analysis. Considering that EME may vary according to the conditions of production and may not reflect the qualitative changes in the children’s discourse, other factors should be analyzed, like the context of the discourse, the participants involved etc.

Educação sexual na escola com a participação da família e o uso de novas tecnologias da educação: um levantamento bibliográfico

This study investigated, by descriptive documental research, the intervention models in Sexual Education in the school with the participation of the family and use of new technologies. The methodological stages were: collects in bases of data, selection and reading of the studies and elaboration of thematic groupings, by the content analysis. Four thematic group were elaborated: 1) intervention models with professionals; 2) intervention models with adolescents; 3) intervention models with the direct participation of the family and 4) Appreciation of the family’s participation in sexual education. The analised articles prioritize the adolescent population, when descrive the intervention. Few studies consider the family as important to sexual education and the techniques of the computer science are not very explored as pedagogic resources.

A comunicação em fóruns de um curso a distância de formação de professores para uso de TDICS: análise da presença de ensino

The importance of the inclusion of digital technology in the classroom has already been pointed out by numerous authors in the educational field and some of them herald that it is through this inclusion that we can achieve transformations in school settings. Based on this assumption, this paper aims to present a distance learning course offered to in service and preservice teachers, focused on the use of technology in foreign language classroom primarily focusing on the role of teacher educators in mediating discussions. For this we sought theoretical support in studies which deal with distance courses (KENSKI, 2008), about virtual environments (ARAÚJO and MARQUESI, 2008), online discussion forums and investigation community and teaching presence (GARRISON, ANDERSON and ARCHER, 2000). Based on the previous theories presented, teacher educator’s messages were analyzed during a distance course offered to teachers in continuing and initial training, identifying marks of teaching presence and pointing to appropriate mediations and/or possible gaps. The results indicate that the teacher must be even more aware of the types of feedback that are provided and of the teaching presence mentioned by Garrison and colleagues (2000, 2001).

Avaliação das alterações dentárias e esqueléticas induzidas pelo uso do aparelho de Herbst no tratamento da classe II na dentadura mista: Revisão sistemática

Objective: evaluate the immediate dental and skeletal changes induced by the Herbst appliance on early treatment of Angle´s Class II malocclusion. Material and Method: several electronic databases such as Scopus, Pub Med, Medline, Cochrane Library, Lilacs and Scielo were searched. The abstracts that fullfilled the selection criteria were selected and those that did not provide enough information about these criteria were selected but the final decision of including them or not on the research, was taken after the complete reading of the article. The selection criteria were: clinical studies with Class II individuals, both male and female, with initial age of 7 to 10 years, treated with the Herbst appliance that analysed the dental and/or skeletal changes evaluated on lateral cephalometric radiographs; researches where the treatment performed did not involve extractions or surgical interventions; studies that included patients without syndromes or health concerns and articles published in English or Portuguese. Results and Conclusions: five articles were selected. The articles showed that significant changes happened in the mandibular sagittal lenght, on facial convexity angle, on maxillo-mandibular relationship, on retroclination of the upper incisors and on distal movement of the upper molars, on proclination of the lower incisors and on extrusion of the lower molars. The appliance exerted a limited effect on the anterior relocation of the maxillary complex and on facial heights. However, more studies about the performance of the Herbst appliance on early treatment of Class II are needed.

Avaliação do uso de Selante de Fibrina derivado do veneno de serpente como arcabouço biológico de células tronco mesenquimais na regeneração óssea do fêmur de ratos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Uso de LH ou eCG no último dia do protocolo superovulatório em bovinos

In the last decades several hormonal treatments to induce multiple ovulation and embryo transfer (MOET) have been developed. Tight control of the time of ovulation allowed the use of fixed-time artificial insemination (FTAI) in bovine embryos donors, facilitating animal management. Although, protocols that allow FTAI have evolved and yield as much embryo as conventional protocols that requires estrus detection, substantial increase in viable embryo production has not been observed in superestimulated bovine cattle. The present review put emphasis on superestimulatory protocols in wich the last two doses of pFSH are replaced by eCG or LH. Recent results indicate that an extra LH stimulus (using eCG or LH), on the last day of P-36 superestimulatory treatment, seems to improve transferable embryo yield in both Bos taurus and Bos indicus cattle.