1000 resultados para Camundongo como animal de laboratório Teses
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t.1 (1817)
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t.2 (1817)
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t.5 (1829)
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v 1 (1831)
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Background: Several researchers seek methods for the selection of homogeneous groups of animals in experimental studies, a fact justified because homogeneity is an indispensable prerequisite for casualization of treatments. The lack of robust methods that comply with statistical and biological principles is the reason why researchers use empirical or subjective methods, influencing their results. Objective: To develop a multivariate statistical model for the selection of a homogeneous group of animals for experimental research and to elaborate a computational package to use it. Methods: The set of echocardiographic data of 115 male Wistar rats with supravalvular aortic stenosis (AoS) was used as an example of model development. Initially, the data were standardized, and became dimensionless. Then, the variance matrix of the set was submitted to principal components analysis (PCA), aiming at reducing the parametric space and at retaining the relevant variability. That technique established a new Cartesian system into which the animals were allocated, and finally the confidence region (ellipsoid) was built for the profile of the animals’ homogeneous responses. The animals located inside the ellipsoid were considered as belonging to the homogeneous batch; those outside the ellipsoid were considered spurious. Results: The PCA established eight descriptive axes that represented the accumulated variance of the data set in 88.71%. The allocation of the animals in the new system and the construction of the confidence region revealed six spurious animals as compared to the homogeneous batch of 109 animals. Conclusion: The biometric criterion presented proved to be effective, because it considers the animal as a whole, analyzing jointly all parameters measured, in addition to having a small discard rate.
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t.2 (1829)
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t.1 (1829)
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v. 7 (1917)
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v. 3 (1913)
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v. 5 (1915)
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v. 4 (1914)
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v. 6 (1916)
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Tese de mestrado em Biologia Humana e Ambiente, apresentada Universidade de Lisboa, atravs da Faculdade de Cincias, 2015
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A elaborao de pequenas quantidades de emulso de carne, em laboratório, pode ser de grande valia no ensino de cincia e tecnologia da carne e no desenvolvimento de certos tipos de pesquisa, por razes de ordem prtica e econmica. No presente trabalho foi estudada a influncia de alguns fatores sobre a estabilidade de emulses de carne obtidas em pequeno triturador de alimentos, tipo cutter, de mesa, com carne magra bovina e gordura suina. Nas condies dos ensaios realizados, verificou-se a possibilidade de serem obtidos sistemas estveis, tendo o pH da carne ou da emulso sido fator limitante. A adio prvia de sal comum carne no foi suficiente para a estabilidade das emulses. Quanto composio qumica da matria-prima, a relao umidade/protena da carne magra do pescoo foi significativamente inferior da carne magra da paleta.
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3 (Plates)