Compostos bioativos dos alimentos e atenção farmacêutica: uma revisão de literatura no quadro da osteoartrite

O Brasil tem passado por uma revolução demográfica importante e, com o crescente número de adultos e idosos, há também o aumento do aparecimento de doenças crônicas não transmissíveis relacionadas ao envelhecimento. Um exemplo é a osteoartrite, uma doença degenerativa, que acomete diferentes articulações do corpo e atinge com mais frequência a população acima de 50 anos de idade. O tratamento farmacológico da doença visa aliviar os sintomas de dor e inflamação com a administração de anti-inflamatórios e analgésicos que apresentam muitos efeitos adversos. Como alternativa para auxiliar o tratamento da osteoartrite, podem ser utilizados compostos bioativos dos alimentos, também chamados nutracêuticos. É reconhecido cientificamente que alguns compostos bioativos presentes nos alimentos possuem, além de sua capacidade nutricional, um papel importante para a prevenção e tratamento de alguns estados clínicos. Este estudo busca analisar, por meio de uma revisão bibliográfica, os benefícios de quatro nutracêuticos, quando utilizados no tratamento da osteoartrite. Dentre os nutracêuticos pesquisados, estão o ácido ascórbico, os insaponificáveis de abacate e soja, a vitamina D e o ômega 3, que auxiliam no tratamento do quadro inflamatório e na reparação da cartilagem danificada. Uma nova perspectiva no auxílio do tratamento da osteoartrite impõe ao farmacêutico adquirir um conhecimento interdisciplinar que possa contribuir para a orientação e informação de pacientes no exercício da atenção farmacêutica, a fim de sanar possíveis dúvidas dos pacientes sobre tais compostos e melhorar o aproveitamento do tratamento na melhoria de sua qualidade de vida.

Utilização de trocadores de calor de placas em espiral em processos da indústria siderúrgica

Stricter environmental policies are shown necessary to ensure an effective pollutant emission control. It is expected for the present year of 2015, that Brazil will assume, at the 21th United Nation's Climate Change Conference (COP21), implementation of commitment to a low carbon economy. This positioning affects the industrial environment, so that is deemed necessary to search for new technologies, less aggressive to the environment, so the adequacies to the new emission policies do not cause a negative effect on production. Almost all of the processes performed in the steel industry demand burning fuel and, therefore, flue gases are sent to the atmosphere. In this present work is discussed the utilization of heat exchangers so, by recovering part of the available heat from the flue gases of certain industrial process, the combustion air is preheated. The combustion air preheat results in less energy requirement, i.e., less need of fuel consumption and, in addition, minor amount of pollutants to be emitted. Due to better fitting to the process, it is studied the utilization of spiral plate heat exchangers. The heat exchanger dimensioning is made by an iterative method implemented in the software Microsoft Excel. Subsequently are analyzed the gains in terms of process's thermal efficiency improvement and the percentage of fuel saving. The latter implies in reduction of the same percentage of greenhouse gases emission

Produção do Espaço Urbano e Dinâmica Imobiliária em Cidades Médias: os casos de Presidente Prudente (SP), São José do Rio Preto (SP) e Lleida (ESP)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Obtenção e caracterização de nanocelulose a partir de fibras de Chorisia speciosa St. Hil

Natural fibers have been highlighted as a renewable material that can replace materials from oil and its derivatives. In this context, Brazil becomes the perfect setting because of the diversity of fibers found in its territory, such as sugarcane, sisal, rice, cotton, coconut, pineapple, among others. The paineiras (Chorisia speciosa St. Hil) are typically Brazilian trees, which produce paina as fruit. These fruits are still little studied as a source of lignocellulose by research groups. This project aimed obtaining and characterization of cellulose nanofibers from the fibers from the paina fibers. Obtaining nanocellulose is practically made through simplified chemical processes. First, was performed out pre-treatments to removal of waxes, lignin and hemicellulose. The first stage of pre-treatment was carried out by alkaline aqueous solution of sodium hydroxide (NaOH) at 5wt%, where the fibers were under constant agitation for 1h at 70°C. Through alkali treatment it was possible to remove most of the lignin, hemicellulose, waxes and extractives. After the alkaline treatment was done bleaching with an aqueous solution of sodium hydroxide (NaOH) to 4wt% and hydrogen peroxide (H2O2) to 24wt% 1:1 during 2h with constant stirring to 50 °C. Through bleaching was possibe to remove residual lignin, and got cellulose with 72% of crystallinity. Nanocellulose of paina fibers was extracted using different conditions of acid hydrolysis with sulfuric acid (H2SO4) to 50wt%. After acid hydrolysis, the suspensions were centrifuged during 30 min and dialyzed in water to remove excess acid until neutral pH (6-7). Then the suspensions were passed by ultrasonification in an ultrasound 20 kHz during 1h in an ice bath. Untreated, alkalinized and bleached fibers as well as cellulose nanoparticles were characterized by the techniques of thermogravimetry ... (Complete abastract click electronic access below)

Estudo da viabilidade da implantação de frotas de veículos elétricos e híbridos elétricos no atual cenário econômico, político, energético e ambiental brasileiro

Currently there are two car models that use electricity in their propulsion systems, the electric vehicle and the hybrid electric vehicle. The electric vehicles are classified as vehicles that use electric motors in their propulsion system and batteries as a power source, on the other hand, the hybrid vehicles are classified as vehicles that use both electric motors and internal combustion engines in their propulsion system, using both batteries and líquid fuels as a power source. The main goal of this work is to analyze the characteristics of electric and hybrid electric vehicles and demonstrate the unfeasibility of the electric vehicle in the current economic, political, energetic and environmental brazilian scenario, for this purpose it was realized a study about the current brazilian situation regarding to electricity generation, current conservation status of road network, lack of electrical infrastructure for charging batteries, national lithium reserves, environmental characteristics, tax incentives, economic scenario, oil market and political positioning related to the implantation of electric or hybrid electric fleets in nacional territory. The operational characteristics analysis of electric and hybrid electric vehicles in this current scenario leads to the conclusion that currently a growth of electric vehicles fleets on a national scale is totally impractical in the Brazil, Thus, the introduction of green vehicles probably will occur primarily with hybrid electric models, motivated mainly due the bigger autonomy of this models compared to electric models, lower cost of hybrid electric models compared to electric models, factors related to the lack of recharging infrastructure and also factors related to political positioning

Aplicação da tecnologia 4G em projetos de telefonia

This paper presents a study based on bibliographic research on LTE technology, chosen for the fourth generation of mobile phones, and the current status of implementation of 4G network in Brazil. The change in user behavior, which now uses data over the voice services, requires transmission networks to be increasingly robust and fast to enable the viewing of videos and use of other platforms that require internet connection. The retrospective of the development of mobile technologies, from 1G up to 4G that is currently used, shows the long road until it came to appliances and how the phone is used nowadays. Finally, the popularity of smartphones and hence the growing number of people with access to 4G networks, demanded new researchs for the development of future generations technologies in order to achieve the demand for speed enabling significant changes in user experience

Gás natural no panorama brasileiro e um estudo de caso no setor automotivo

The intended purpose of this paper is to present the main aspects of natural gas applied to the public transportation as well as the environmental, economical and technical impacts in this sector. Also it is given specific information to be considered when comparing natural gas to other fuels, specially the diesel. At this point is presented the types of internal combustion engines (Otto and Diesel cycle) and which type is used in each vehicle. Moreover, it is presented the main standards pollutant emission (Euro, US and Proconve) with a brief explanation of the tests made in order to approve the engines. This paper is focused on heavy duty vehicles. Also in this paper is exposed the economic impact due to the natural gas use in the public transportation fleet. In addition is presented a real case (of Berlin) and an estimative to a Brazilian city, presenting the potential of natural gas as vehicular fuel in Brazil, as well as financial and environmental aspects of the substitution

EDiferentes tipologias de edificação e o ser sustentável mediante o LEED e o CBCS

The principles and dimensions of sustainability concept is increasingly gaining ground within the building industry. Over the past decades, its applicability within the different environments and for different buildings typologies have been study to attend better the present populations and future generations. It is within this scenario that international certifications started to appear. The most famous and developed one being LEED certification system. In Brazil, as a support to the certification and also sustainability practices and conducts, was founded the Brazilian Council for Sustainable Construction (CBCS). The council and the certifications have the objective to disseminate and generate awareness to reduce energy and water consumption, aiming for life quality. Many constructions around de country have already the international certification, which also boost the rise of national certifications with specific criteria for the national context. However, such certificates are mainly destiny for medium and high standard buildings, often as a commercial advantage to explain the high costs. The purpose of this work is to be able to define what is being sustainable in the construction industry, taking for basis, LEED and CBCS. In addition, since there is a significant increase in the production of Housing Social Interest, the other angles will be to analyze how to apply the practices and sustainable technologies for low-cost projects with the objective to balance the three dimensions of sustainability: environmental, social and economics.

Infraestrutura de data center e suas tendências com foco em eficiência energética

With the Big Data development and the growth of cloud computing and Internet of Things, data centers have been multiplying in Brazil and the rest of the world. Designing and running this sites in an efficient way has become a necessary challenge and to do so, it's essential a better understanding of its infrastructure. Thus, this paper presents a bibliography study using technical concepts in order to understand the specific needs related to this environment and the best forms address them. It discusses the data center infrastructure main systems, methods to improve their energy efficiency and their future trends

Freio eletrodinamométrico usando um inversor de frequência e um motor de indução trifásico

Considering that the Brazilian energy source is based on hydroelectric power plants, every moment that it does not rain enough, we are likely to suffer power outage. Making the rational use of energy not only is wise, but also important for financial issues. The industrial sector is of great importance to Brazilian economic context, because it is one that creates more wealth and jobs. It should be noted that it is one of the sectors that consume more electricity. One of the most used equipment in industry is the three phase induction motor, which ends up providing significant waste of energy. For that reasons, studying three phase induction motors is important. One of the ways to evaluate the parameter of the three phase induction motor is using a dynamometer mechanic or electric. This work aims at further studies (and development) of electrodynamometer brake, a type of electrical dynamometer, that is the only one with reversible use. This means, it is possible to measure both the torque and the power transmitted by the electric motors, by the direct method and the indirect. Besides it allows greater stability in the imposition of charges, due to its nature of being able to regenerate the energy imparted by the engines being tested

Produção enxuta aplicada à construtoras de pequeno e médio porte

Against the current need of improvements in construction processes and increased competitiveness on Construction Industry in Brazil, lean construction concepts have spread all over the market, achieving small and medium enterprises. In reason of this, the monograph it is a research based on interviews of small and medium construction enterprises from Vale do Paraíba, São Paulo, Brazil, that focus in identify practices of lean construction implementation and barriers to incorporate these concepts on them. Besides the research, it will be done an analysis and some suggestions to overcome the obstacles appeared

Geração distribuída de energia elétrica e panorama fotovoltaico brasileiro e português

This work presents a study on the design of a photovoltaic system connected to the grid.It discussed the main characteristics of the solar cell which is the basic component for the manufacture of solar modulethe main components of the photovoltaic system and the steps of the photovoltaic and electrical design of the system, ranging from the choice of the photovoltaic module to the dimensioning of the components of the electrical installation.In addition to the technical design, this work contains a complete comparative analysis of the current situation of photovoltaic generation distributed in Brazil and Portugal, through incentive programs to energy use as well as current legislation in both countries

Torneamento da liga de alumínio da classe 6005 utilizando ferramenta cerâmica

Machining processes are one of the most important manufacturing processes in the modern world. In these processes, there are many elements which will influence in the final result of the machined part. Among them, the tools are the principal factor of the rising cost, because its global influence on the process. In aeronautical industries, this can be more evidenced due the need to machining several alloys, between them, aluminum alloys. These alloys have to demonstrate a specific surface finishing to be used in aircraft's fuselage. This kind of industry is one of the segments which is still rising in Brazil, and they are looking viable alternatives in the manufacturing processes of materials, due the need to produce more and more parts and equipment, with costs increasingly reduced. The purpose of this project is the development of a ceramic with differentiated properties. The ceramics were developed using a pre-sintering at 1200 °C, with posterior sintering at 1600°C, and subjected to dry turning process on aluminum alloy 6005. The characterizations showed that ceramics presented with toughness on the center of 1700 MPa and on the surface of 1950 MPa, density 98,5 ±0,14. g/cm³. Ceramics were grinded and faceted, according to ISO standard 1832, and subjected to turning tests in a ROMI lathe brand, model GL240M, using cutting speeds of 500, 800 and 1000 m/min with different feed rates. The machining results showed low occurrence of flank wear to all cutting speeds, and better surface finishing average values of Ra = 0,4935 μm and Rt = 8,112 μm. In general, it could be seen that the tool presents important potential to machining 6005 alloy, and that the use of correct parameters can decrease and/or eliminate subsequent processes, providing important reductions in costs related to the machining processes

Desenvolvimento da linguagem oral em crianças afastadas da família de origem

For a complete development of oral language it's necessary the development of genetic roots of thought and utterance postulates by Vygotsky, yet the meditation of adult and the influence social and cultural that is around the child. In cases of children moved away from their birth family by judicial ways because of neglect there, is a new modality of refuge in Brazil, that is the home refuge, which is the object of our research. The present study shows an investigation about the development of speech in a child that was moved away from his birth family and forwarded to Foster Family to comprehend the contributions and activities that help in child development. The research was performed through an approach of qualitative interpretation of bibliographic type and area type. The data analysis allowed us conclude the new social and cultural way that the watched child was inserted helps in his development in a significant way enabling a qualitative jump in speech and psychic functions phase

Estudo da viabilidade de implantação do INOVAR-AUTO utilizando o método do fluxo de caixa sob risco

The automobile industry has a growing importance in the Brazilian economic environment. The industry moves a huge chain that encompasses manufacturers, suppliers of raw materials, auto parts dealers, gas stations, insurance companies, repair shops, tire stores, media companies, advertising agencies, among others. Because of this importance in the current economic environment in Brazil, the federal government, through Law No. 12715 of 17 December 2012 established a Program for the Promotion of Innovation and Densification in the Productive Chain of Motor Vehicles called INOVAR-AUTO in order to support technological development, innovation, safety, environmental protection, energy efficiency and quality of cars, trucks, buses and auto parts. The specific purpose of this study, a simulation for discussion of the viability of the program implementation using the Monte Carlo Simulation combined with the Cash-Flow-at-Risk was performed. To this end, an exploratory and documentary literature on the subject was held as well as a case study in a automobile company of Japanese origin