Induction of the gene encoding mucosal vascular addressin cell adhesion molecule 1 by tumor necrosis factor alpha is mediated by NF-kappa B proteins.

Mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) is involved in trafficking of lymphocytes to mucosal endothelium. Expression of MAdCAM-1 is induced in the murine endothelial cell line bEnd.3 by tumor necrosis factor alpha (TNF-alpha), interleukin 1, and bacterial lipopolysaccharide. Here we show that TNF-alpha enhances expression of a firefly luciferase reporter directed by the MAdCAM-1 promoter, confirming transcriptional regulation of MAdCAM-1. Mutational analysis of the promoter indicates that a DNA fragment extending from nt -132 to nt +6 of the gene is sufficient for TNF-alpha inducibility. Two regulatory sites critical for TNF-alpha induction were identified in this region. DNA-binding experiments demonstrate that NF-kappa B proteins from nuclear extracts of TNF-alpha-stimulated bEnd.3 cells bind to these sites, and transfection assays with promoter mutants of the MAdCAM-1 gene indicate that occupancy of both sites is essential for promoter function. The predominant NF-kappa B binding activity detected with these nuclear extracts is a p65 homodimer. These findings establish that, as with other endothelial cell adhesion molecules, transcriptional induction of MAdCAM-1 by TNF-alpha requires activated NF-kappa B proteins.

Analytical method to measure bending deformations in prismatic optical films

The aim of this work is to provide an analytical method based on experimental measurements in order to obtain the prismatic film deformation for different curvatures of Hollow Cylindrical Prismatic Light Guides (CPLG). To conform cylindrical guides is necessary bend the film to guide the light, changes induced by curving the film give rise to deformation shifts. Light losses affected by deformation has been experimentally evaluated and numerically analyzed. The effect of deformation in prism angle is specially increased for CPLG of curvatures higher than 20 m-1. An experimental method for accurate transmittance measurements related to bending is presented.

Fadiga cíclica flexural de instrumentos Hyflex CM e TF Adaptive em diferentes situações experimentais

O presente estudo teve como objetivo avaliar a resistência à fadiga cíclica flexural dos instrumentos de níquel- titânio, Hyflex CM (Coltène, EUA) e TF Adaptive (SybronEndo, EUA) em diferentes situações experimentais. Todas as limas que foram selecionadas possuíam conicidade 0,04 e diâmetro de ponta 35. Utilizou-se um dispositivo desenvolvido especificamente para realizar o ensaio flexural dinâmico. Os instrumentos TF Adaptive foram divididos em 3 grupos de acordo com o ângulo de curvatura do ensaio: 45º, 60º e 90º e cada grupo subdividido em 2 subgrupos de acordo com o tipo de movimento: rotação contínua e Adaptive. Cada subgrupo era composto por 15 instrumentos TF Adaptive, totalizando 90 instrumentos. Quinze instrumentos Hyflex CM formavam o grupo 4, no ensaio com ângulo de curvatura 90 graus e rotação contínua. A simulação foi realizada em canais artificiais de aço com ângulo de 45, 60, 90 graus e raio 5m m. O número de ciclos e o tempo em segundos até a fratura foram tabulados e analisados. Entretanto, a fadiga cíclica flexural foi significante maior nos três grupos em movimento Adaptive. E as limas TF Adaptive em seu próprio movimento tiveram maior número de ciclos e tempo até a fratura quando comparadas as Hyflex CM no ensaio de 90 graus. Portanto, conclui-se que o sistema Adaptive (limas TF Adaptive + movimento Adaptive) foi mais seguro à resistência á fadiga flexural, e no ensaio de 90 graus o sistema Adaptive foi mais resistente quando comparado com as limas Hyflex CM no movimento de rotação contínua.

Estudo experimental do comportamento à fratura frágil em aços estruturais ferríticos e aplicações à determinação da curva mestra.

Este trabalho apresenta uma investigação experimental sobre o comportamento à fratura frágil de aços estruturais ferríticos, ASTM A285 Gr C e ASTM A515 Gr 65. Os resultados deste trabalho ampliam a base de dados de propriedades mecânicas utilizadas nas análises de integridade de estruturas pressurizadas tais como vasos de pressão e tanques de armazenamento construídos com esta classe de material. O trabalho tem por objetivo também avaliar a aplicabilidade de corpos de prova de dimensões reduzidas, PCVN, na determinação da temperatura de referência, T0, por meio da metodologia da Curva Mestra, a qual define a dependência da tenacidade à fratura do material em função da temperatura. Os ensaios de tenacidade à fratura foram conduzidos utilizando-se corpos de prova solicitados em flexão três pontos com geometria SE(B), PCVN e PCVN com entalhe lateral, extraídos de chapas laminadas. Os resultados dos ensaios foram obtidos em termos de integral J no momento da instabilidade, denotados por Jc. Dados adicionais de resistência à tração e de Impacto Charpy convencional também foram obtidos para caracterizar o comportamento mecânico dos aços utilizados. Os resultados mostraram uma forte influência da geometria dos corpos de prova sobre os valores de Jc, evidenciada pela grande variação nos valores de tenacidade à fratura.

Asar-i Şeyh Seyyid Mustafa Beyzade

Terceme-yi ahval-i Beyzade Mustafa Efendi -- Mevlid ün-Nebi -- Menasik ül-hac -- Naẓm al-nāṣiḥīn -- Silsilat al-Naqshabandīyah -- Muqaddimat al-Qaṣīdah al-durrīyah -- al-Qaṣīdah al-durrīyah -- Qaṣāʼid -- Şeyh Hafiz Mehmed al-Hisari'nin tarih-i irtihali -- Taqrīḍ Sharḥ al-Qāmūs -- Taqrīḍ Sharḥ al-Iḥyāʼ -- Murtaza Efendi'nin kaside-yi sabikaya takrizidir -- Beyzade Efendinin Yusufzade'ye verdiği icazetname -- Murad Molla Tekyesi şeyhi Abdülhalim Efendi'ye verdiği izinname -- Boluvi el-Hac Mustafa Efendi'ye verdiği icazetname -- Halil Efendi'ye verdiği icazetname -- Rizevi Ali Efendi'ye verilen icazetname -- Murtaza Efendi'nin Beyzade Efendi'ye i[r]sal eylediği mektub -- Beyzade Efendi'den Murtaza Efendi'ye tahrir olunan mektub -- Geyve Müftüsü Efendi'ye tahrir olunmuştur -- Kastamonu Müftüsüne irsal olunan mektubudur -- Hafiz Efendi'nin Beyzade Efendi'ye yazdıkları tezkire -- Beyzade Efendi hazretlerinin tezkireye cevapları -- Risālat al-Sulūk lil-Shaykh Beyzade -- Çorumlu Ebubekir Efendi'nin risale-yi manzumelerine takrizdir -- Cevab-ı mektub -- Medhiye-yi Abdülkadir el-Geylani -- İşbu salat-i şerife Beyzade Efendiden mervidir -- Risālat al-maʻlūm wa-al-majhūl.

Şerh-i kasaid-i Mevlânâ Şevket

Commentary by Mehmed Murad Nakşbendi. Cf. İstanbul Üniversitesi Kütüphanesi Türkçe basmalar alfabe kataloğu, v. 2 (1956), p. 772.

Swiss Banking Secrecy; The Erosion of an Institution. IES WORKING PAPER 2/2008

Switzerland has for a long time been an important centre of banking services in Europe and beyond. Consequently, the banking sector has become important to Switzerland’s prosperity. This paper focuses on a central reason behind the success of the Swiss banking sector: the institution of banking secrecy, deeply enshrined in the Swiss history and tradition. The rapid development of international markets that eventually gave rise to a “group structuration process” has, however, progressively eroded Swiss banking secrecy. It has had to bend before the duty of transparency within the groups in order not to promote financial criminality through accelerated asset inflows. Switzerland has also had to develop a comprehensive legislative frame to tackle financial criminality, and to enter into international agreements providing for mutual assistance. This process has undoubtedly and irremediably weakened the Swiss banking secrecy. Most importantly, nevertheless, the questionable ethical and socio-economic grounds of this controversial institution could and should also start to erode it from within.

Kent County, Michigan investigation of possible airline airport sites with recommendations of two feasible sites to serve the Kent County area /

"February, 1958."

Corporation annual reports to shareholders.

2nd ser. 1951-1970 v.1 Ac-Ac is oversize and is on the bottom shelf of locator 168. 2nd ser. 1951-1970 suppl. is located on top shelf of locator 170.

Growing older in Illinois : needs, challenges, opportunities.

"This report was written by the Heartland Center on Aging, Disability and Long Term Care, School of Public and Environmental Affairs, Indiana University and the National Center for Senior Living, South Bend, Indiana. May, 1991." Acknowledgements.

Report to the House of Representatives, Illinois General Assembly, in accordance with House Resoulution 1893 /

House Resolution 1893 directed the Dept. to investigate the financial difficulties of the South Shore Railroad and make recommendations to the General Assembly by July 1, 1989.

Wenger memoirs and autobiography of Martin Light Wenger and his wife Christina Studebaker : together with the home history and genealogy of their posterity to the present time /

Mode of access: Internet.

The heart of Oregon : legend of the Wascos /

In verse.

Christmas eve on Lonesome "Hell-fer-sartain" and other stories /

Frontispiece and plates facing p. 20, 40, 78, 168 and 226.

National wilderness preservation act. Hearing, Eighty-fifth Congress, second session, on S. 4028, a bill to establish a national wilderness preservation system for the permanent good of the whole people, and for other purposes.

Hearings concluded on November 14, 1958.