Die Geschichte der "Königswarter-Stiftung" in Meran 1872 - 1907 : [... Rafael Hausmann zur Feier seines 70. Geburtstages ...]

von A.Tänzer

Prognostic factors and risk groups in T1G3 non-muscle-invasive bladder cancer patients initially treated with Bacillus Calmette-Guérin: results of a retrospective multicenter study of 2451 patients

BACKGROUND The impact of prognostic factors in T1G3 non-muscle-invasive bladder cancer (BCa) patients is critical for proper treatment decision making. OBJECTIVE To assess prognostic factors in patients who received bacillus Calmette-Guérin (BCG) as initial intravesical treatment of T1G3 tumors and to identify a subgroup of high-risk patients who should be considered for more aggressive treatment. DESIGN, SETTING, AND PARTICIPANTS Individual patient data were collected for 2451 T1G3 patients from 23 centers who received BCG between 1990 and 2011. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS Using Cox multivariable regression, the prognostic importance of several clinical variables was assessed for time to recurrence, progression, BCa-specific survival, and overall survival (OS). RESULTS AND LIMITATIONS With a median follow-up of 5.2 yr, 465 patients (19%) progressed, 509 (21%) underwent cystectomy, and 221 (9%) died because of BCa. In multivariable analyses, the most important prognostic factors for progression were age, tumor size, and concomitant carcinoma in situ (CIS); the most important prognostic factors for BCa-specific survival and OS were age and tumor size. Patients were divided into four risk groups for progression according to the number of adverse factors among age ≥ 70 yr, size ≥ 3 cm, and presence of CIS. Progression rates at 10 yr ranged from 17% to 52%. BCa-specific death rates at 10 yr were 32% in patients ≥ 70 yr with tumor size ≥ 3 cm and 13% otherwise. CONCLUSIONS T1G3 patients ≥ 70 yr with tumors ≥ 3 cm and concomitant CIS should be treated more aggressively because of the high risk of progression. PATIENT SUMMARY Although the majority of T1G3 patients can be safely treated with intravesical bacillus Calmette-Guérin, there is a subgroup of T1G3 patients with age ≥ 70 yr, tumor size ≥ 3 cm, and concomitant CIS who have a high risk of progression and thus require aggressive treatment.

Festschrift Professor Dr. Maybaum zum 70. Geburtstag : (29. April 1914)

gewidmet von seinen Schülern

Festskrift i anledning af Professor David Simonsens 70-aarige Fødselsdag

Nir Daṿid likhvod ha-rav he-ḥakham R. Daṿid Simonsen

Festschrift zum 70. Geburtstage des Oberkirchenrats Dr. Kroner

hrsg. vom Württemberg. Rabbiner-Verein

Festschrift zu Ehren des Dr. A. Harkavy aus Anlass seines am 20. November 1905 vollendeten 70. Lebensjahre : gewidmet von Freunden und Verehrern

Hrsg. von Baron D. von Günzburg

Treu und frei : ges. Reden u. Vorträge über Juden u. Judentum von M. Lazarus : [mit] Lebensbild zu seinem 70. Geburtstage am 15. Sept. 1894

von M. Brasch

Festschrift zum 70. Geburtstag von Moritz Schaefer : zum 21. Mai 1927

hrsg. von ... Philipp Aronstein [u.a.]

Isak Noa Mannheimer, Prediger : eine biographische Skizze ; mit Benützung von Archivalien d. k.k. Staats- u. Justizministerien, d. k.k. obersten Gerichtshofes, d. k.k. niederösterreichischen Statthalterei u. d. Wiener Magistrates (zur Feier d. 70. Geburtstages, am 17. Oct. 1863)

von G. Wolf

Types of Jewish-Palestinian piety : from 70 B.C.E. to 70 C.E. ; the ancient pious men

by Adolph Büchler

Ms. hebr. oct. 70 - Ḥidushim al Ḥoshen mishpaṭ u-derushim

Vorbesitzer: Abraham Merzbacher

Ms. Barth. 70 - Consilia

Vorbesitzer: Bartholomaeusstift Frankfurt am Main

In Börnes Aufsatz: "Juden in Frankfurt a. M." : (Börnes Schriften VI, S. 66 - 70)

L. G.