A single phosphotyrosine residue of the prolactin receptor is responsible for activation of gene transcription.

Members of the cytokine/growth hormone/prolactin (PRL) receptor superfamily are associated with cytoplasmic tyrosine kinases of the Jak family. For the PRL receptor (PRLR), after PRL stimulation, both the kinase Jak2 and the receptor undergo tyrosine phosphorylation. To assess the role of tyrosine phosphorylation of the PRLR in signal transduction, several mutant forms of the PRLR in which various tyrosine residues were changed to phenylalanine were constructed and their functional properties were investigated. We identified a single tyrosine residue located at the C terminus of the PRLR to be necessary for in vivo activation of PRL-responsive gene transcription. This clearly indicates that a phosphotyrosine residue in the cytoplasmic domain of a member of the cytokine/growth hormone/PRL receptor superfamily is directly involved in signal transduction.

Preliminary data on horse mackerel (Trachurus spp) landings from Mauritanian waters

European fishery off Mauritania (one of the most productive and most intensively exploited regions in the world) targeted to small pelagic fish accounts for 30% of the total catches in the area. The Instituto Español de Oceanografía (IEO), through its Centro Oceanográfico de Canarias, follows up the activity of these vessels that land at Spanish port (Las Palmas de Gran Canaria, Spain), under the European Project Data Collection (Regulation (EC) 1543/2000). One of the target groups in this fishery is Trachurus spp, commercially named “JAX”. During 2008 and 2009, several samples of this group from these landings were analysed, and Caranx rhonchus was the second species of importance. The mixture of these species in the landings of this UE fleet should be determined to improve the data provided to the international Working Groups responsible for assessment of those resources.