396 resultados para Zen Zen Zo


Relevância:

10.00% 10.00%

Publicador:

Resumo:

On cover of atlas: Cordoba durchmusterung. Mapas. 1893.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Includes bibliographical references and index.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Appeared in part as the author's inaugural dissertation, Würzburg, 1912, under title: Die zölle im system der deutschen handelsverträge (vi, 121 p.).

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Inaug.-diss.--Heidelberg.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Includes index.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Tight junctions are directly involved in regulating the passage of ions and macromolecules (gate functions) in epithelial and endothelial cells. The modulation of these gate functions to transiently regulate the paracellular permeability of large solutes and ions could increase the delivery of pharmacological agents or gene transfer vectors. To reduce the inflammatory responses caused by tight junction-regulating agents, alternative strategies directly targeting specific tight junction proteins could prove to be less toxic to airway epithelia. The apical delivery of peptides corresponding to the first extracellular loop of occludin to transiently modulate apical paracellular flux has been demonstrated in intestinal epithelia. We hypothesized that apical application of these occludin peptides could similarly modulate tight junction permeability in airway epithelia. Thus, we investigated the effects of apically applied occludin peptide on the paracellular permeability of molecular tracers and viral vectors in well differentiated human airway epithelial cells. The effects of occludin peptide on cellular toxicity, tight junction protein expression and localization, and membrane integrity were also assessed. Our data showed that apically applied occludin peptide significantly reduced transepithelial resistance in airway epithelia and altered tight junction permeability in a concentration-dependent manner. These alterations enhanced the paracellular flux of dextrans as well as gene transfer vectors. The occludin peptide redistributed occludin but did not alter the expression or distribution of ZO-1, claudin-1, or claudin-4. These data suggest that specific targeting of occludin could be a better-suited alternative strategy for tight junction modulation in airway epithelial cells compared with current agents that modulate tight junctions.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Dit boek is bestemd voor teamleden of begeleiders die het werken in een team zo effectief mogelijk willen maken. De auteur behandelt allerlei aspecten van het werken in teams. Aan de hand van voorbeelden maakt hij duidelijk welke factoren het effectief functioneren van een team kunnen verbeteren of tegenwerken. Het boek bevat ook richtlijnen om de dynamiek van een team te bevorderen. Dit boek is een vertaling van het boek Effective teamwork. Het is uitermate relevant voor veel beroepen in de openbare en particuliere sector: handel en bedrijfsleven, onderwijs, gezondheidszorg en maatschappelijke dienstverlening.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Binnen veel organisaties staat de marketingafdeling onder druk. Resultaten moeten op korte termijn zichtbaar zijn en de afdeling krijgt intern soms een slechte pers. In dit boek worden de tien belangrijkste, meest actuele problemen van marketing, hun oorzaken én mogelijke oplossingen besproken. Marketing aan de top biedt zo een beknopte, maar sterk onderbouwde handreiking voor iedere marketeer en marketingmanager die zijn vak relevanter en waardevoller wil maken. Ook voor topmanagers en managers actief in functionele gebieden buiten de marketing biedt het boek inzicht in de rol die de marketingfunctie kan spelen om de organisatie als geheel succesvoller te maken.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

The goal of this dissertation is to explore the use of transgressive language in the works of Juan Goytisolo and Zoé Valdés. This study examines the socio-political and cultural contexts in which the narrative of both authors develops, as well as the textual devices employed by these writers for undermining the “official history” imposed by the dictatorial regimes in Francoist Spain and Castro's Cuba. Furthermore, this dissertation argues that the deconstructing strategies in Goytisolo and Valdés mark their literary trajectory. Their vindicatory standpoints seek an alternative discourse of national identity. ^ The function of language in demythifying and recodifying hegemonic discourse is examined in Goytisolo's trilogy Señas de identidad, Reivindicación del conde don Julián, and Juan sin tierra; and the novels of Zoé Valdés La nada cotidiana and Te di la vida entera. The parallelisms in the literary works of Goytisolo and Valdés are established by contrasting the authors' revisionist approach to history, the self-reflexivity of their novels, the sexual referent, and the use of irony and parody. The theoretical framework incorporates poststructuralist theorists such as Todorov, Foucault, Lacan, Barthes, Derrida, and Kristeva; the psychoanalytical theory of Freud; and the feminist theories of Cixous and Irigaray. The comparative approach of this study and the interplay of power, politics, aesthetic creation, and author's psychology provide an illuminating perspective that could be of interest to individuals from a variety of disciplines. ^