Perfil hemostático e hematológico de equinos com compactação de cólon maior submetidos ao tratamento medicamentoso

Pós-graduação em Medicina Veterinária - FCAV

Vias oblíquas da trasncendência: aspectos do idealismo em Augusto dos Anjos e Pedro Kilkerry

This essay analyzes the manifestations of the idealism of romantic orientation in the poetry of Augusto dos Anjos and Pedro Kilkerry, showing the points of contact between their oeuvres and demonstrating that many of the innovative aesthetic procedures of their poetry appear as a reaction to urgencies of an idealistic conception of poetry. Augusto dos Anjos and Pedro Kilkerry attest the anxiety of apprehension of connections with a super-sensible sphere in phenomenal reality. Although this takes a different form in each of the poets, it can refer to a common poetic ideal that transcends the concrete reality. To accomplish this, they use aesthetic procedures that modernize the language of the romantic sublime – Augusto dos Anjos uses a hybrid philosophical repertoire that marks his poetry with a tense and innovative prosaic language, and Pedro Kilkerry opts for the indirect representation, made by an evocative and metonymic language, that evidences the mystery of the transcendent ideal without deciphering it.

Imunofenótipos de linfócitos T no sangue e no liquor de cães com leishmaniose visceral: correlação com as lesões encefálicas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Signos neurológicos asociados a pacientes caninos con linfoma

Cancer alters the structure or functions of adjacent organs with their sole presence, and subsequent clinical manifestations, but can also cause harmful effects in distant organs. These clinical changes induced by non-invasive tumor action are of great clinical diversity and are known as paraneoplastic syndromes. This paper describes four cases of canine patients with neurological disorders associated to generalized superficial lymphadenopathy.

Sintomas auditivos e desordens temporomandibulares

Introduction: A variety of hypotheses have been proposed to explain the association between temporomandibular disorders and hearing symptoms, including the many anatomical and/or neurological ways, as of a muscle or joint dysfunction, can cause such symptoms. Objective: The purpose of this study is to discuss, through a systematic review of literature, the interrelation between hearing symptoms and temporomandibular disorders. Material and Methods: We consulted the Medline/PubMed, ISI and Scielo in the period 1918 to 2008. The terms related to the research were: “temporomandibular disorders”, “signs and symptoms of temporomandibular disorders”, “otologic symptoms” and “aural symptoms”, where 19 papers were included using the pre-selected criteria for the manufacture of a meta-analysis. Results: According to the findings, the hearing symptoms most often associated with temporomandibular disorders were otalgia and tinnitus, followed by vertigo and hearing loss, respectively. Conclusions: It’s clear the correlation between hearing symptoms and temporomandibular disorders, however there is a need clinical and scientific research more complex to prove the specific cause-effect relationships between them.

Doença de Lyme na região de cabeça e pescoço: implicações para a odontologia

Lyme disease (LD) is a systemic inflammatory changes resulting from the direct action of the spirochete Borrelia burgdorferi on the host or indirect damage produced by immune response to this microorganism. This pathogen is transmitted by inoculation in the bloodstream by the tick genus Ixodes and is most commonly found in North America, Europe and Asia. In these regions, the dental community is aware about its commonest clinical symptoms, collaborating with the establishment of a diagnosis. However, in Brazil, the frequent facial or peripheral neurological manifestations, among them the Bell's palsy, ocular disorders, disorders in the temporomandibular joint, as well as paresthesia of upper and lower alveolar nerves are observed. In our country, the diagnosis of Lyme disease is primarily based on clinical symptomatology, but most of cases remain without diagnosis and treatment. Then, the detection of the early manifestations of Lyme disease by health professionals is essential for the proper antibiotic treatment, preventing the progression of the disease, and allowing the establishment of favorable prognostic.

Implicações clínicas da doença de Lyme em região facial: revisão da literatura

Lyme disease (LD) is a systemic infl ammatory changes resulting from direct action and the immune response to the spirochete Borrelia burgdoferi transmitted by inoculation of the fl ow of the genus Ixodes tick and is most commonly found in North America, Europe and Asia. This disease can lead to facial and peripheral neurological manifestations, such as Bell’s palsy, eye changes, disorders in the temporo-mandibular joint in addition to paresthesia of superior and inferior alveolar nerves. In Brazil, the diagnosis of LD is primarily based on clinical presentation, the erythema migrans skin, and epidemiological information of the patient. Recognition of the onset of the DL by health professionals is essential for the correct antibiotic treatment preventing the progression of the disease, and also relevant preventive guidelines for those living or working in endemic areas.

Selección del tratamiento farmacológico en el estado de mal epiléptico en niños

The status epilepticus (SE) is characterized by a series of crises which occur without recovery of consciousness or a single seizure lasting more than 30 minutes and can damage the central nervous system and systemic. The duration and frequency of attacks are directly related to patient prognosis. Whether seizures occur often and are longer, increase the risk of neurological and systemic complications. Child population has a higher frequency of seizures and it is associated with a lower threshold of immature brain to trigger these episodes. Aim: To determine the safest drugs prescribed for children in SE, their doses and schedules. A bibliographic survey was performed in electronic databases. Methods: The scientific health descriptors used for search was: “status epilecticus” and “anticonvulsivants” and “child”. Results: This strategy identified 396 manuscripts, of whom four were considered eligible for the study, after the assessment by floating reading and criteria. Of these, two were randomized trials and two descriptive. The studies address the use of oral midazolam, rectal diazepam and intravenous lorazepam. Conclusions: All investigated drugs were effective in treat in status epilepticus. Lorazepam is highlight, since it has fewer secondary effects and, as an alternative to the intravenous, oral midazolam. However, there is a need for further studies to demonstrate the efficacy and safety in the use of drugs in children.

Borreliosis in horses: epidemiology, experimental infection and therapeutic

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Doença cerebelar em cães e gatos

Diseases of the cerebellar system are common in small animals, and result in a clinical syndrome characterized by hypermetria, base-wide stance and intentional tremors of the head and body. All movements of the limbs are spastic and awkward. The neurological examination assists in the localization of lesions restricted to the cerebellum or in the detection of disorders relating to other parts of the nervous system, which characterizes a multifocal disease process. Neurological disorders in dogs and cats may suggest a very extensive list of differential diagnoses, since they may be caused by infectious, degenerative and traumatic processes, among others. The possible etiologies for cerebellar syndrome include: aplasia and hypoplasia, abiotrophy, cancer, vascular stroke and inflammatory disorders. The aim of this paper is to review the clinical signs that aid in the location of the cerebellar lesion and discuss the possible causes of this syndrome in dogs and cats.

Meningite supurativa secundária a otite média e interna em um gato: relato de caso

Suppurative meningitis are rarely reported in dogs and cats. The present study aims to report the occurrence of suppurative meningitis secondary to otitis media and interna in a five-year-old female Persian cat examined at the Veterinary School of Unesp-Botucatu with acute progressive multifocal neurological alterations. Analysis of the cerebrospinal fluid (CSF) demonstrated predominance of neutrophils (90%) and the presence of bacteria. Therapy with antibiotics was initiated, but the animal came to die. beta-hemolytic Staphylococcus, beta-hemolytic Streptococcus and Proteus mirabilis were detected in fragments sent to culture. The present report demonstrates the importance of performing more specific exams such as complete CSF analysis in cases of otitis media and interna. This way, central nervous infections can be diagnosed and treated in a timely manner, as those are acute diseases with poor prognosis.

Glioma misto em um cão: relato de caso

Intracranial neoplasms are common causes of neurological disorders in middle-aged and elderly dogs. With the feasibility of computed tomography, it is now possible to determine the extent and exact location of brain tumors, identifying them ante mortem in dogs and cats. This paper aims to report the occurrence of a mixed glioma in a Boxer dog examined at the Veterinary Hospital of Unesp, Botucatu Campus. The animal presented with a brain syndrome of acute onset and progressive course. CT scan showed the presence of a mass in the right cerebral hemisphere extending from the frontal to the parietal region and involving the basal ganglia. Given the gravity of the neurological disorder, the owner chose to perform euthanasia. Microscopic analysis of the mass allowed the diagnosis of mixed glioma.

Influência de gênero e do ciclo estral no reflexo auditivo de sobressalto em ratos Wistar

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

The influence of speech stimuli contrast in cortical auditory evoked potentials

Studies about cortical auditory evoked potentials using the speech stimuli in normal hearing individuals are important for understanding how the complexity of the stimulus influences the characteristics of the cortical potential generated. OBJECTIVE: To characterize the cortical auditory evoked potential and the P3 auditory cognitive potential with the vocalic and consonantal contrast stimuli in normally hearing individuals. METHOD: 31 individuals with no risk for hearing, neurologic and language alterations, in the age range between 7 and 30 years, participated in this study. The cortical auditory evoked potentials and the P3 auditory cognitive one were recorded in the Fz and Cz active channels using consonantal (/ba/-/da/) and vocalic (/i/-/a/) speech contrasts. Design: A crosssectional prospective cohort study. RESULTS: We found a statistically significant difference between the speech contrast used and the latencies of the N2 (p = 0.00) and P3 (p = 0.00) components, as well as between the active channel considered (Fz/Cz) and the P3 latency and amplitude values. These correlations did not occur for the exogenous components N1 and P2. CONCLUSION: The speech stimulus contrast, vocalic or consonantal, must be taken into account in the analysis of the cortical auditory evoked potential, N2 component, and auditory cognitive P3 potential.

O conceito de morte e a Síndrome de Asperger

O conceito de morte é adquirido paralelamente ao desenvolvimento cognitivo e afetivo da criança, sendo descritos três estágios, paralelos aos estágios piagetianos. O objetivo deste trabalho foi verificar se o conceito de morte em portadores da síndrome de Asperger é similar ao observado em pessoas sem psicopatologia, ou se tem relação com o observado em portadores de deficiência intelectual leve. Para tanto, foram avaliados indivíduos com síndrome de Asperger, indivíduos com deficiência intelectual leve e indivíduos sadios, sem doenças mentais e/ou neurológicas, utilizando-se o Instrumento de Sondagem do Conceito de Morte elaborado por Wilma Torres. Os resultados apontam deficits na aquisição do conceito de morte por indivíduos com síndrome de Asperger, possivelmente relacionados aos deficits na teoria da mente, função executiva e fraca coerência central.