954 resultados para South San Francisco
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La realización del Plan Estratégico de Mercadeo es el resultado del trabajo que se ha realizado en conjunto con la Asociación Barra de Santiago, con el objetivo de brindar apoyo al grupo de mujeres de escasos recursos y con deseos de superación tanto económico como social y que de esta manera sean parte del desarrollo del Cantón El Zapote y por consiguiente del país. Para la realización se utilizaron diferentes herramientas metodológicas tales como: la observación directa, una guía de entrevistas dirigida a la Directora Ejecutiva de la Asociación y al Grupo de mujeres que elabora la jalea de mango, también se elaboró un cuestionario dirigido a los habitantes del Cantón El Zapote y a los turistas que visita La Barra de Santiago. Los resultados obtenidos de los diagnósticos son: a) La Asociación Barra de Santiago ha realizado una muy buena gestión local debido a que ha apoyado el desarrollo de la zona a través de proyectos y programas que benefician a sus habitantes; b) Un factor que incide negativamente en el desarrollo del proyecto de jalea de mango es que año con año las integrantes del grupo que son alumnas que estudian noveno grado, deben abandonar el proyecto porque al concluir los estudios en esta escuela ya no les permiten continuar en él y c) A pesar que la jalea de mango que produce el grupo de mujeres posee un buen sabor, color y consistencia, el precio ($1.00) al que actualmente es vendida no va de acuerdo a la calidad de ésta y no refleja su verdadero valor. Esta situación puede solventarse con la aplicación del Plan Estratégico de Mercadeo cuyo propósito principal es proveer una guía de cómo comercializar la jalea de mango. Debido a esto la Asociación Barra de Santiago junto con el grupo de mujeres debe enfocar sus intereses en implementar el proyecto, la época en la que no exista producción se sugiere que el grupo de mujeres se integren a los otros proyectos que ejecuta la Asociación Barra de Santiago como lo son el cultivo de tilapia, flor de Jamaica y huertos hidropónicos.
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40 p.
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Resumen El artículo pretende determinar el peso de lo material y lo cultural como factores fundamentales del levantamiento rural en la región de Chalco, México. Entre 1760 y 1920 se producen una serie de cambios en la estructura económica y social de esa región que revelan la ofensiva de la hacienda comercial en detrimento de los recursos comunales de los pueblos. Esto genera una serie de conflictos agrarios de los cuales este artículo analiza uno, el de 1868, ya que su análisis permite considerar y discutir la naturaleza esencial del movimiento social, ponderando el componente anarquista con la dimensión ambientalista del mismo. El autor se encuentra un discurso reivindicativo de los recursos naturales que considera ?ambientalista? por ser una defensa del modo de vida de los pueblos y no sólo de un recurso ?ambiental?, mismo que inserta en la reflexión global sobre la encrucijada entre conflicto y negociación en la región de Chalco. Abstract This essay analyzes material and cultural explanations of rural rebellions in Chalco, Mexico between 1760 and 1920. In that period, several social and economic changes took place which reveal the consolidation of the commercial hacienda against pueblos communal resources. This situation produced several agrarian conflicts; this paper analyses one of those conflicts: that of 1868. The study of that conflict discloses the composition of the rural movement in its anarchist and environmental dimensions. This paper argues that the pueblos defended their natural resources and consequently their way of life by using an ?environmentalist? discourse. Such a discourse was inserted at a crossroads of conflict and negotiation in Chalco.
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In this study, we analyzed the ABCD1 gene in X-linked adrenoleukodystrophy (X-ALD) patients and relatives from 38 unrelated families from South America, as well as phenotypic proportions, survival estimates, and the potential effect of geographical origin in clinical characteristics. Methods: X-ALD patients from Brazil, Argentina and Uruguay were invited to participate in molecular studies to determine their genetic status, characterize the mutations and improve the genetic counseling of their families. All samples were screened by SSCP analysis of PCR fragments, followed by automated DNA sequencing to establish the specific mutation in each family. Age at onset and at death, male phenotypes, genetic status of women, and the effect of family and of latitude of origin were also studied. Results: We identified thirty-six different mutations (twelve novel). This population had an important allelic heterogeneity, as only p. Arg518Gln was repeatedly found (three families). Four cases carried de novo mutations. Intra-familiar phenotype variability was observed in all families. Out of 87 affected males identified, 65% had the cerebral phenotype (CALD). The mean (95% CI) ages at onset and at death of the CALD were 10.9 (9.1-12.7) and 24.7 (19.8-29.6) years. No association was found between phenotypic manifestations and latitude of origin. One index-case was a girl with CALD who carried an ABCD1 mutation, and had completely skewed X inactivation. Conclusions: This study extends the spectrum of mutations in X-ALD, confirms the high rates of de novo mutations and the absence of common mutations, and suggests a possible high frequency of cerebral forms in our population.
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Rhodoliths are nodules of non-geniculate coralline algae that occur in shallow waters (<150 m depth) subjected to episodic disturbance. Rhodolith beds stand with kelp beds, seagrass meadows, and coralline algal reefs as one of the world's four largest macrophyte-dominated benthic communities. Geographic distribution of rhodolith beds is discontinuous, with large concentrations off Japan, Australia and the Gulf of California, as well as in the Mediterranean, North Atlantic, eastern Caribbean and Brazil. Although there are major gaps in terms of seabed habitat mapping, the largest rhodolith beds are purported to occur off Brazil, where these communities are recorded across a wide latitudinal range (2 degrees N - 27 degrees S). To quantify their extent, we carried out an inter-reefal seabed habitat survey on the Abrolhos Shelf (16 degrees 50' - 19 degrees 45'S) off eastern Brazil, and confirmed the most expansive and contiguous rhodolith bed in the world, covering about 20,900 km(2). Distribution, extent, composition and structure of this bed were assessed with side scan sonar, remotely operated vehicles, and SCUBA. The mean rate of CaCO3 production was estimated from in situ growth assays at 1.07 kg m(-2) yr(-1), with a total production rate of 0.025 Gt yr(-1), comparable to those of the world's largest biogenic CaCO3 deposits. These gigantic rhodolith beds, of areal extent equivalent to the Great Barrier Reef, Australia, are a critical, yet poorly understood component of the tropical South Atlantic Ocean. Based on the relatively high vulnerability of coralline algae to ocean acidification, these beds are likely to experience a profound restructuring in the coming decades.
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Background: Most investigations regarding the First Americans have primarily focused on four themes: when the New World was settled by humans; where they came from; how many migrations or colonization pulses from elsewhere were involved in the process; and what kinds of subsistence patterns and material culture they developed during the first millennia of colonization. Little is known, however, about the symbolic world of the first humans who settled the New World, because artistic manifestations either as rock-art, ornaments, and portable art objects dated to the Pleistocene/Holocene transition are exceedingly rare in the Americas. Methodology/Principal Findings: Here we report a pecked anthropomorphic figure engraved in the bedrock of Lapa do Santo, an archaeological site located in Central Brazil. The horizontal projection of the radiocarbon ages obtained at the north profile suggests a minimum age of 9,370640 BP, (cal BP 10,700 to 10,500) for the petroglyph that is further supported by optically stimulated luminescence (OSL) dates from sediment in the same stratigraphic unit, located between two ages from 11.7 +/- 0.8 ka BP to 9.9 +/- 0.7 ka BP. Conclusions: These data allow us to suggest that the anthropomorphic figure is the oldest reliably dated figurative petroglyph ever found in the New World, indicating that cultural variability during the Pleistocene/Holocene boundary in South America was not restricted to stone tools and subsistence, but also encompassed the symbolic dimension.
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Background Increased mortality among men on antiretroviral therapy (ART) has been documented but remains poorly understood. We examined the magnitude of and risk factors for gender differences in mortality on ART. Methods and Findings Analyses included 46,201 ART-naïve adults starting ART between January 2002 and December 2009 in eight ART programmes across South Africa (SA). Patients were followed from initiation of ART to outcome or analysis closure. The primary outcome was mortality; secondary outcomes were loss to follow-up (LTF), virologic suppression, and CD4+ cell count responses. Survival analyses were used to examine the hazard of death on ART by gender. Sensitivity analyses were limited to patients who were virologically suppressed and patients whose CD4+ cell count reached >200 cells/µl. We compared gender differences in mortality among HIV+ patients on ART with mortality in an age-standardised HIV-negative population. Among 46,201 adults (65% female, median age 35 years), during 77,578 person-years of follow-up, men had lower median CD4+ cell counts than women (85 versus 110 cells/µl, p<0.001), were more likely to be classified WHO stage III/IV (86 versus 77%, p<0.001), and had higher mortality in crude (8.5 versus 5.7 deaths/100 person-years, p<0.001) and adjusted analyses (adjusted hazard ratio [AHR] 1.31, 95% CI 1.22–1.41). After 36 months on ART, men were more likely than women to be truly LTF (AHR 1.20, 95% CI 1.12–1.28) but not to die after LTF (AHR 1.04, 95% CI 0.86–1.25). Findings were consistent across all eight programmes. Virologic suppression was similar by gender; women had slightly better immunologic responses than men. Notably, the observed gender differences in mortality on ART were smaller than gender differences in age-standardised death rates in the HIV-negative South African population. Over time, non-HIV mortality appeared to account for an increasing proportion of observed mortality. The analysis was limited by missing data on baseline HIV disease characteristics, and we did not observe directly mortality in HIV-negative populations where the participating cohorts were located. Conclusions HIV-infected men have higher mortality on ART than women in South African programmes, but these differences are only partly explained by more advanced HIV disease at the time of ART initiation, differential LTF and subsequent mortality, and differences in responses to treatment. The observed differences in mortality on ART may be best explained by background differences in mortality between men and women in the South African population unrelated to the HIV/AIDS epidemic.
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BACKGROUND: The provision of highly active antiretroviral therapy (HAART) in resource-limited settings follows a public health approach, which is characterised by a limited number of regimens and the standardisation of clinical and laboratory monitoring. In industrialized countries doctors prescribe from the full range of available antiretroviral drugs, supported by resistance testing and frequent laboratory monitoring. We compared virologic response, changes to first-line regimens, and mortality in HIV-infected patients starting HAART in South Africa and Switzerland. METHODS AND FINDINGS: We analysed data from the Swiss HIV Cohort Study and two HAART programmes in townships of Cape Town, South Africa. We included treatment-naïve patients aged 16 y or older who had started treatment with at least three drugs since 2001, and excluded intravenous drug users. Data from a total of 2,348 patients from South Africa and 1,016 patients from the Swiss HIV Cohort Study were analysed. Median baseline CD4+ T cell counts were 80 cells/mul in South Africa and 204 cells/mul in Switzerland. In South Africa, patients started with one of four first-line regimens, which was subsequently changed in 514 patients (22%). In Switzerland, 36 first-line regimens were used initially, and these were changed in 539 patients (53%). In most patients HIV-1 RNA was suppressed to 500 copies/ml or less within one year: 96% (95% confidence interval [CI] 95%-97%) in South Africa and 96% (94%-97%) in Switzerland, and 26% (22%-29%) and 27% (24%-31%), respectively, developed viral rebound within two years. Mortality was higher in South Africa than in Switzerland during the first months of HAART: adjusted hazard ratios were 5.90 (95% CI 1.81-19.2) during months 1-3 and 1.77 (0.90-3.50) during months 4-24. CONCLUSIONS: Compared to the highly individualised approach in Switzerland, programmatic HAART in South Africa resulted in similar virologic outcomes, with relatively few changes to initial regimens. Further innovation and resources are required in South Africa to both achieve more timely access to HAART and improve the prognosis of patients who start HAART with advanced disease.
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Mode of access: Internet.
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Mode of access: Internet.
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"May 1981."
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Other editions published under title: 1895: Forms and precedents; 1918: Form book; 1933: Forms.
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Mode of access: Internet.
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Mode of access: Internet.
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Accompanied by bound supplement (v. 3, 3161-4207 p.) by Curtis Hillyer, published in 1926.