Reports of cases argued and determined in the Arches and Prerogative Courts of Canterbury, and in the High Court of Delegates : containing judgments of the Right Hon. Sir George Lee /

Title on spine: Lee Arches & Prerogative Courts.

The correspondence between Great Britain and France on the subject of the late negotiation : presented by His Majesty's command to both houses of Parliament, 13th [i.e. 18th] May, 1803 : to which are added, His Majesty's declaration, and copies of the preliminary and definitive treaties of peace.

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A historical account of His Majesty's visit to Scotland.

Mode of access: Internet.

[Coronation of King Edward VII].

Mode of access: Internet.

Special double number of the Illustrated London news. The lying-in-state of King Edward VII.

Advertising matter included in paging.

Memoirs of the Geological survey of England and Wales. vol. I[-IV, pt. I]. /

Title varies: volume 1, Memoirs of the Geological survey of Great Britain, and of the Museum of economic geology in London. volumes 2-3, Memoirs of the Geological survey of Great Britain, and of the Museum of practical geology.

The life of His Royal Highness the prince consort,

Mode of access: Internet.

Correspondenz von Leibniz mit der Prinzessin Sophie, Enkelin des Königs Jakob I. von England, geb. Pfalzgräfin bei Rhein, verm. Herzogin später Kurfürstin von Braunschweig-Lüneburg, seit 1701 pr. Thronerbin von Grossbritannien und Irland. 1680-1714. Hauptsächlich aus den Leipniz-Papieren der Königlichen Bibliothek zu Hannover.

Mode of access: Internet.

Proceedings and ordinances of the Privy Council of England ...

Printed by command of His Majesty King William IV in pursuance of an address of the House of Commons of Great Britain and under the direction of the commissioners of the public records of the kingdom.

A letter from the king...

Poem: "When Sir John Barleycorn was free" tipped in.

The visitation of the county of Lincoln made by Sir Edward Bysshe, knight, Clarenceux king of arms, in the year of Our Lord 1666 /

Mode of access: Internet.

Syndromic and non-syndromic aneurysms of the human ascending aorta share activation of the Smad2 pathway

Common features such as elastic fibre destruction, mucoid accumulation, and smooth muscle cell apoptosis are co-localized in aneurysms of the ascending aorta of various aetiologies. Recent experimental studies reported an activation of TGF-beta in aneurysms related to Marfan (and Loeys-Dietz) syndrome. Here we investigate TGF-beta signalling in normal and pathological human ascending aortic wall in syndromic and non-syndromic aneurysmal disease. Aneurysmal ascending aortic specimens, classified according to aetiology: syndromic MFS (n = 15, including two mutations in TGFBR2), associated with BAV (n = 15) or degenerative forms (n = 19), were examined. We show that the amounts of TGF-beta 1 protein retained within and released by aneurysmal tissue were greater than for control aortic tissue, whatever the aetiology, contrasting with an unchanged TGF-beta 1 mRNA level. The increase in stored TGF-beta 1 was associated with enhanced LTBP-I protein and mRNA levels. These dysiregulations of the extracellular ligand are associated with higher phosphorylated Smad2 and Smad2 mRNA levels in the ascending aortic wall from all types of aneurysm. This activation correlated with the degree of elastic fibre fragmentation. Surprisingly, there was no consistent association between the nuclear location of pSmad2 and extracellular TGF-beta 1 and LTBP-I staining and between their respective mRNA expressions. In parallel, decorin. was focally increased in aneurysmal media, whereas biglycan was globally decreased in aneurysmal aortas. In conclusion, this study highlights independent dysregulations of TGF-beta retention and Smad2 signalling in syndromic and non-syndromic aneurysms of the ascending aorta. Copyright (C) 2009 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

InovCity – structure of trials evaluation

A Work Project, presented as part of the requirements for the Award of a Masters Degree in Management from the NOVA – School of Business and Economics

Inovcity- Structure of trials evaluation

In 2007, the UK government commissioned the Energy Demand Research Project to conduct a large scale experiment of smart metering technologies to test the impacts from many different forms of feedback to residential consumers. A full evaluation of the results was completed in 2011. In Portugal, EDP is also conducting smart meter trials in a project called InovCity in the city of Évora whose results will be evaluated during 2012. In this work, the case of Great Britain is studied as a reference on how an evaluation of trial results should be conducted. I also discuss potential limitations of the experiments, implications for national roll-out decisions, and finally draw some lessons that can be applied to the Portuguese case.

Leaving the labour market: event-history analysis of the female workers' transition to housework in Denmark, Germany, Great Britain and Spain

This paper is aimed at exploring the determinants of female activity from a dynamic perspective. An event-history analysis of the transition form employment to housework has been made resorting to data from the European Household Panel Survey. Four countries representing different welfare regimes and, more specifically, different family policies, have been selected for the analysis: Britain, Denmark, Germany and Spain. The results confirm the importance of individual-level factors, which is consistent with an economic approach to female labour supply. Nonetheless, there are significant cross-national differences in how these factors act over the risk of abandoning the labour market. First, the number of trnasitions is much lower among Danish working women than among British, German or Spanish ones, revealing the relative importance of universal provision of childcare services, vis-à-vis other elements of the family policy, as time or money.