Schutzbrief and marriage permit for Bonuit Hayum, granted by Friedrich August, Herzog zu Nassau, Wiesbaden

Schutzbrief and marriage permit for Bonuit Hayum, granted by Friedrich August, Herzog zu Nassau, Wiesbaden, manuscript and seal; includes English translation

Hans Ernst Brisch Collection 1912-1995

M.A. Pach, 1995

Directional dominance on stature and cognition in diverse human populations

Homozygosity has long been associated with rare, often devastating, Mendelian disorders1, and Darwin was one of the first to recognize that inbreeding reduces evolutionary fitness2. However, the effect of the more distant parental relatedness that is common in modern human populations is less well understood. Genomic data now allow us to investigate the effects of homozygosity on traits of public health importance by observing contiguous homozygous segments (runs of homozygosity), which are inferred to be homozygous along their complete length. Given the low levels of genome-wide homozygosity prevalent in most human populations, information is required on very large numbers of people to provide sufficient power3, 4. Here we use runs of homozygosity to study 16 health-related quantitative traits in 354,224 individuals from 102 cohorts, and find statistically significant associations between summed runs of homozygosity and four complex traits: height, forced expiratory lung volume in one second, general cognitive ability and educational attainment (P < 1 × 10−300, 2.1 × 10−6, 2.5 × 10−10 and 1.8 × 10−10, respectively). In each case, increased homozygosity was associated with decreased trait value, equivalent to the offspring of first cousins being 1.2 cm shorter and having 10 months’ less education. Similar effect sizes were found across four continental groups and populations with different degrees of genome-wide homozygosity, providing evidence that homozygosity, rather than confounding, directly contributes to phenotypic variance. Contrary to earlier reports in substantially smaller samples5, 6, no evidence was seen of an influence of genome-wide homozygosity on blood pressure and low density lipoprotein cholesterol, or ten other cardio-metabolic traits. Since directional dominance is predicted for traits under directional evolutionary selection7, this study provides evidence that increased stature and cognitive function have been positively selected in human evolution, whereas many important risk factors for late-onset complex diseases may not have been.

Paluu paratiisiin : Polkuja hyvän ja pahan tuolle puolen Martti Lutherin ja Friedrich Nietzschen perinteissä

Tutkimukseni tarkoitus on paikallistaa polkuja hyvän ja pahan tuolle puolen. Tutkimukseni termit hyvä ja paha määrittyvät moraalisesti. Täten tutkimusaiheeni on ihmisen ja moraalin välinen suhde. Tutkin ihmisen moraalista olotilaa, siinä tapahtuvaa muutosta ja tämän muutoksen ehtoja. Tutkimuksellani on kaksi pääkysymystä: kuinka on mahdollista päästä hyvän ja pahan tuolle puolen ja miksi meidän tulisi siirtyä hyvän ja pahan tuolle puolen. Polut hyvän ja pahan tuolle puolen vievät myös etiikan tuolle puolen. Tutkimukseni pyrkii selvittämään mitä vikaa etiikassa on ja kuinka on mahdollista perustella toimintaa ilman etiikkaa. Tutkimukseni metodi on systemaattinen analyysi. Johdanto-osassa käsittelen yleisesti moraalia, sen vaikutuspiiriä ja niitä syitä, joiden vuoksi se täytyy hylätä. Tarkastelen myös etiikkaa ja selvitän sitä laajempaa kontekstia mihin se liittyy. Ensimmäisessä luvussa käsittelen Martti Lutherin teologiaa. Lutherilla moraalia edustaa Jumalan laki, jonka alaisuudesta kristitty pääsee vapaaksi kun Jeesus ottaa ristinkuolemassaan ihmisten synnin itselleen ja kärsii Jumalan lain mukaisen kuolemanrangaistuksen. Uskon yhteydessä Kristukseen kristitty kohoaa lain ulkopuolelle tekemään rakkauden tekoja. Toinen luku on omistettu Søren Kierkegaardin kristilliselle eksistentialismille. Kierkegaardin eksistenssitasojen filosofiassa uskonnollinen olemisen taso paljastuu korkeammaksi kuin eettinen. Tässä nousee tärkeäksi Kierkegaardin kirja Pelko ja vavistus. Kierkegaard tutkii Raamatun kertomusta Aabrahamista, jolle Jumala antaa käskyn uhrata oma poikansa Iisak. Kierkegaardille tarina on esimerkki eettistä korkeammasta ja sitä tilapäisesti vastustavasta olemisen tavasta. Kolmannessa luvussa käsittelen Dietrich Bonhoefferin teologiaa. Bonhoefferin mukaan Jeesus kutsuu ihmisiä seuraamaan häntä. Tämä on kutsu hyvän ja pahan tuolle puolen paratiisin viattomuuteen, joka rikkoo eettisyyden ihmisen ja Jeesuksen välillä. Neljännessä luvussa tarkastelen Friedrich Nietzschen filosofiaa ja pyrin ymmärtämään mitä hänen ohjelmansa hyvän ja pahan tuolle puolen tarkoittaa. Nietzschen vallantahdon filosofiassa moraali on heikkojen keino alistaa vahvat. Tarkastelen Nietzschen käsitystä moraalin synnystä ja sen haitallisuudesta ja pyrin selvittämään kuinka herrat elävät hyvän ja pahan tuolla puolen. Viidennessä luvussa tutkin Jaques Derridan grammatologiaa. Derridan mukaan teksti on suljettu tila, jonka ulkopuolelle on mahdoton päästä. Derrida sanoittaa kuitenkin sanoittamatonta tilattomuutta tekstin tuolla puolen. Tästä ei-paikasta käsin hypereettinen dekonstruktio purkaa perinteistä etiikkaa. Kuudennessa luvussa tarkastelen Mark C. Taylorin epä/teologiaa. Taylorille olotilan muutosta kuvaa termi harhautuminen , joka vie ihmisen lainsuojattomuuteen hyvän ja pahan tuolle puolen. Selvitän mitä harhautuminen tarkoittaa ja miten se liittyy Taylorin Jumalan kuoleman epä/teologiaan. Johtopäätösluvussa tuon esiin tutkimustuloksia, nostan esille joitain pääluvuissa esiintyviä teemoja ja vertaan tutkimuskohteitteni näkemyksiä toisiinsa. Lutherin ja Nietzschen perinteissä on paljon yhteistä, mutta pohjimmiltaan ne sotivat toisiaan vastaan. Hyvän ja pahan tuolle puolen johtaa kaksi polkua. Toinen niistä vie paratiisiin, toinen tuhoon.

Trajectories of charged particles in the static Ernst space-time

The authors study the trajectories of charged particles in Ernst's space-time representing a static black hole immersed in a magnetic field. They find bound orbits always exist for realistic magnetic field strengths. A similar investigation is carried out for the case of Melvin's magnetic universe and for a corresponding test field superposed on a flat space-time.

The German Military Entrepreneur Ernst von Mansfeld and His Conduct of Asymmetrical Warfare in the Thirty Years War

The dissertation examines aspects of asymmetrical warfare in the war-making of the German military entrepreneur Ernst von Mansfeld during his involvement in the Thirty Years War. Due to the nature of the inquiry, which combines history with military-political theory, the methodological approach of the dissertation is interdisciplinary. The theoretical framework used is that of asymmetrical warfare. The primary sources used in the dissertation are mostly political pamphlets and newsletters. Other sources include letters, documents, and contemporaneous chronicles. The secondary sources are divided into two categories, literature on the history of the Thirty Years War and textbooks covering the theory of asymmetrical warfare. The first category includes biographical works on Ernst von Mansfeld, as well as general histories of the Thirty Years War and seventeenth-century warfare. The second category combines military theory and political science. The structure of the dissertation consists of eight lead chapters, including an introduction and conclusion. The introduction covers the theoretical approach and aims of the dissertation, and provides a brief overlook of the sources and previous research on Ernst von Mansfeld and asymmetrical warfare in the Thirty Years War. The second chapter covers aspects of Mansfeld s asymmetrical warfare from the perspective of operational art. The third chapter investigates the illegal and immoral aspects of Mansfeld s war-making. The fourth chapter compares the differing methods by which Mansfeld and his enemies raised and financed their armies. The fifth chapter investigates Mansfeld s involvement in indirect warfare. The sixth chapter presents Mansfeld as an object and an agent of image and information war. The seventh chapter looks into the counter-reactions, which Mansfeld s asymmetrical warfare provoked from his enemies. The eighth chapter offers a conclusion of the findings. The dissertation argues that asymmetrical warfare presented itself in all the aforementioned areas of Mansfeld s conduct during the Thirty Years War. The operational asymmetry arose from the freedom of movement that Mansfeld enjoyed, while his enemies were constrained by the limits of positional warfare. As a non-state operator Mansfeld was also free to flout the rules of seventeenth-century warfare, which his enemies could not do with equal ease. The raising and financing of military forces was another source of asymmetry, because the nature of early seventeenth-century warfare favoured private military entrepreneurs rather than embryonic fiscal-military states. The dissertation also argues that other powers fought their own asymmetrical and indirect wars against the Habsburgs through Mansfeld s agency. Image and information were asymmetrical weapons, which were both aimed against Mansfeld and utilized by him. Finally, Mansfeld s asymmetrical threat forced the Habsburgs to adapt to his methods, which ultimately lead to the formation of a subcontracted Imperial Army under the management and leadership of Albrecht von Wallenstein. Therefore Mansfeld s asymmetrical warfare ultimately paved way for the kind of state-monopolized, organised, and symmetrical warfare that has prevailed from 1648 onwards. The conclusion is that Mansfeld s conduct in the Thirty Years War matched the criteria for asymmetrical warfare. While traditional historiography treated Mansfeld as an anomaly in the age of European state formation, his asymmetrical warfare has begun to bear resemblance to the contemporary conflicts, where nation states no longer hold the monopoly of violence.

J. B. S. Haldane, Ernst Mayr and the Beanbag Genetics Dispute

Starting from the early decades of the twentieth century, evolutionary biology began to acquire mathematical overtones. This took place via the development of a set of models in which the Darwinian picture of evolution was shown to be consistent with the laws of heredity discovered by Mendel. The models, which came to be elaborated over the years, define a field of study known as population genetics. Population genetics is generally looked upon as an essential component of modern evolutionary theory. This article deals with a famous dispute between J. B. S. Haldane, one of the founders of population genetics, and Ernst Mayr, a major contributor to the way we understand evolution. The philosophical undercurrents of the dispute remain relevant today. Mayr and Haldane agreed that genetics provided a broad explanatory framework for explaining how evolution took place but differed over the relevance of the mathematical models that sought to underpin that framework. The dispute began with a fundamental issue raised by Mayr in 1959: in terms of understanding evolution, did population genetics contribute anything beyond the obvious? Haldane's response came just before his death in 1964. It contained a spirited defense, not just of population genetics, but also of the motivations that lie behind mathematical modelling in biology. While the difference of opinion persisted and was not glossed over, the two continued to maintain cordial personal relations.

La Celestina en escenarios argentinos : observaciones comparatistas sobre las adaptaciones de Jorge Goldenberg (1993) y Daniel Suárez Marzal (2007)

Integran este número de la revista ponencias presentadas en Studia Hispanica Medievalia VIII: Actas de las IX Jornadas Internacionales de Literatura Española Medieval, 2008, y de Homenaje al Quinto Centenario de Amadis de Gaula.

Collecção das Leis do Imperio do Brasil de 1834

Parte 1 - Leis

El cólera en las transformaciones del siglo XIX en Álava. La epidemia de 1834

747 p. (Bibliogr.: 521-546]

Der Sängerkrieg auf der Wartburg. El tema de la lid de los poetas y su recepción literaria en Novalis, E. T. A. Hoffmann, Friedrich de la Motte Fouqué y Richard Wagner

282 págs.Correo electrónico: bea.muro@gmail.com

O período de Garrett na Bélgica (1834-1836) em Memorias Biographicas (de Gomes de Amorim, 1881-1884) e em A Lua de Bruxelas (de Amadeu Lopes Sabino, 2000)

O propósito desta dissertação é analisar o período no qual Almeida Garrett esteve em Bruxelas (1834-1836) como Encarregado de Negócios Estrangeiros e Cônsul Geral de Portugal. Para isso, serão tomadas como base as obras Garrett Memorias Biographicas (1881-1884) de Francisco Gomes de Amorim e A Lua de Bruxelas (2000) de Amadeu Lopes Sabino. Estas obras apresentam as dificuldades financeiras de Garrett, devido ao desprezo do governo português. A biografia é marcada pelo discurso moldado de Amorim, por causa da forte relação de amizade que teve com Garrett, sendo este seu pai literário. Já Sabino apresenta um romance centrado nessa temporada, misturando narrativa histórica, dados biográficos e ficção. Dessa forma, neste trabalho, os discursos serão comparados, explicitando o tom específico de cada um: ambos apresentam as relações do intelectual com o país e com a sociedade, em uma época de grandes mudanças; porém, Amorim guarda um certo verniz e silencia sobre alguns acontecimentos, principalmente relacionados ao casamento de Garrett. Sabino tem, nesse relacionamento com a esposa (Luísa Midosi), o teor do seu romance documentado, se pautando exatamente a partir do que Amorim deixa como enigma

Sentimental education: a study of George Eliots Daniel Deronda

A dissertação analisa Daniel Deronda, de George Eliot, identificando o conceito de maleabilidade como idéia chave para o entendimento dos ideais morais do romance. Discussão do papel desempenhado pelo conceito de maleabilidade no processo de transição da infância para a idade adulta e na apreensão especifica da amizade apresentados no romance

Os caminhos da instrução pública elementar em Maricá de 1834 a 1854

Este trabalho de pesquisa buscou compreender como ocorriam e quais eram as ações no campo das políticas públicas para a instrução primária no século XIX no município de Maricá. Escolhemos como recorte temporal o período do século compreendido entre os anos de 1834 e 1854. A escolha das duas datas se prendeu ao fato de que este período contempla algumas mudanças importantes no campo das políticas públicas para a educação e instrução. Em 1834 temos o Ato Adicional à Constituição de 1824 que delega para as províncias competências para legislar e gerir a instrução primária e secundária. Em 1849 ocorre a implantação do Regulamento Couto Ferraz na província do Rio de Janeiro e, em 1854, o então Ministro do Império encaminha a reforma do ensino na Corte. A proximidade do município com a capital da província e com a Corte pode ser considerado como um dos fatores que instigou a nossa curiosidade em verificar até que ponto esta aproximação contribuiu para o crescimento de Maricá. No decorrer da pesquisa, começamos a perceber que os ritmos de crescimento e desenvolvimento foram diferentes, a cidade continuou como rota de passagem por muitos anos, mesmo com a sua importância econômica (produção agrícola e o pescado), mercado de abastecimento regional. A proximidade com a capital da Província do Rio de Janeiro (Niterói) e a Corte não garantiu à cidade de Maricá crescimento do número de escolas públicas primárias, foio que se verificou ao longo do período analisado. Além da pesquisa bibliográfica sobre o tema utilizamos também como fonte as publicações dos memorialistas locais, os relatórios dos presidentes da província do Rio de Janeiro, assim como documentos disponíveis no Arquivo Público do Estado do Rio de Janeiro.