Ultrasound evaluation of synovitis in RA: correlation with clinical disease activity and sensitivity to change in an observational cohort study.

OBJECTIVE To evaluate the correlation between clinical measures of disease activity and a ultrasound (US) scoring system for synovitis applied by many different ultrasonographers in a daily routine care setting within the Swiss registry for RA (SCQM) and further to determine the sensitivity to change of this US Score. METHODS One hundred and eight Swiss rheumatologists were trained in performing the Swiss Sonography in Arthritis and Rheumatism (SONAR) score. US B-mode and Power Doppler (PwD) scores were correlated with DAS28 and compared between the clinical categories in a cross-sectional cohort of patients. In patients with a second US (longitudinal cohort), we investigated if change in US score correlated with change in DAS and evaluated the responsiveness of both methods. RESULTS In the cross-sectional cohort with 536 patients, correlation between the B-mode score and DAS28 was significant but modest (Pearson coefficient r = 0.41, P < 0.0001). The same was true for the PwD score (r = 0.41, P < 0.0001). In the longitudinal cohort with 183 patients we also found a significant correlation between change in B-mode and in PwD score with change in DAS28 (r = 0.54, P < 0.0001 and r = 0.46, P < 0.0001, respectively). Both methods of evaluation (DAS and US) showed similar responsiveness according to standardized response mean (SRM). CONCLUSIONS The SONAR Score is practicable and was applied by many rheumatologists in daily routine care after initial training. It demonstrates significant correlations with the degree of as well as change in disease activity as measured by DAS. On the level of the individual, the US score shows many discrepancies and overlapping results exist.

Der erste Lese- und Sprachunterricht im Hebräischen und Deutschen : nebst einigen sprachlichen Vorbereitungsübungen zum leichtern Uebersetzen der Miḳra ḳodesh

von Michael Wolf

Ner le-Yiśraʾel

von J. B. Levy. Mit [eingedr.] Zeichnungen von Erna Pinner

Neginot Yiśraẻl (Neginot Israel) : Synagogen-Gesänge für Solo, Soli und Chor ; mit und ohne Orgelbegleitung

componirt von Max Goldstein

Shire Yiśraʼel : gottesdienstliche Gesänge ; eingeführt in der Synagoge zu Bunzlau und in anderen Gemeinden

bearb. und hrsg. von M. Tintner ...

Torat ṭaʿame ha-miḳra : M. Danielis Weimari s. Doctrina accentuationis Hebraeae VI regulis accurate ÿ& succincte inclusa.../ Ipsam Hanc instauravit ; Gottfried Mathesius adjutor

Text lat. u. hebr.

Ṭaʻam ṭaʻame ha-miḳra

auctore Daniele Weimaro

Reshimah mi-sefarim rabim, ḥashuvim, yeḳarim u-meʾod nikhbadim : miḳra, mishnah, talmud bavli ... mi-ʿizvon ... Meʾir Lipmans ...

In hebr. Schr. und Sprache

El male raḥamim : synagogal-liturgischer Trauergesang auf ... den Kaiser und König Wilhelm I. ; für eine Singstimme mit Orgelbegleitung

componirt von Ed. Birnbaum

Reshimat sifre Yiśraʾel : ha-nimtsaʾim be-otsar ha-sefarim asher le-ha-profesor Daniyel Ḥṿolzon

Mit Exlibris Frhr. Carl v. Rothschildsche öffentl. Bibliothek, Geschenk von S. L. Baer

Or Meʾir : kolel reshimat sifre Yiśraʾel, kitve yad ṿe-nidpasim, ha-nimtsaʾim be-vet otsar sefarim ha-gadol shel ... Meʾir Zultsberger be-Filadelfya; ʿim heʿarot, maʾamarim ṿe-shirim mi-kitve yad shonim ...

me-et Efrayim Deinard

Ḥamiššā ḥumšê Tôrā : ʿim qeṣat pērûš Rašî ... we-gam hā-hafṭārôt ... we-5 megîllôt û-birkôt hat-Tôrā ...

[Jehuda Ben-Moses Naphtali]

Ḥamiššā ḥumšê Tôrā : we-hû tiqqûn sôferîm ʿim pērûš Raš"i ...

[Isaak Ben-Simson ha-Kohen]

Ms. hebr. fol. 17 - Ṿa-yiḳra

Bemerkungen: Fragment umfaßt Kap. 1, Vers 5 bis Kap. 8, Vers 17