Sacred time after emigration : a study of the Holy Mother Festival in Zavoj

In Zavoj, a mountainous village in the Republic of Macedonia, the Day of the Holy Mother is the most significant day in the village's ritual calendar. The Day of the Holy Mother, like other holy days associated with saints, is a religious festival in the Eastern Orthodox liturgical calendar; and Zavoj, like other villages, identifies with a particular holy day, in this case that of the Holy Mother. Festival is historically and etymologically linked to feast, a celebration in honour of gods, and the Day of the Holy Mother, like the two principal feasts in the Christian calendar, the Feast of Nativity of our Lord (Christmas) and the Feast of Resurrection (Easter), is a religious celebration that includes a feast in honour of the saint, traditionally as a breaking of a fast. Importantly, many Zavoj emigrants return to the village for the festival on the Day of the Holy Mother. Over recent years both village and the festival have been transformed, due to large and continuing emigration and the demise of the resident peasant generation. This chapter will examine the changes in the festival, comparing that of 1988, when the village was inhabited, with that of 2007, when there were only a few people resident and by which time many of the peasant generation had passed on. As a result of emigration the village is emptied of its inhabitants, yet it remains the site of, and destination for, the continuity of the annual festival.

Nicotine dependence in a prospective population-based study of adolescents : the protective role of a functional tyrosine hydroxylase polymorphism

Dopamine is a key neurotransmitter of the mesolimbic reward pathway in the human brain, and tyrosine hydroxylase (TH) is the rate-limiting enzyme in dopamine biosynthesis. Consequently, the gene encoding TH is a strong candidate for involvement in the genetic component of addiction. The importance of this gene in nicotine dependence is supported by many studies showing a link between nicotine administration and TH expression. A functional tetranucleotide repeat polymorphism within intron 1 of the TH gene (HUMTH01-VNTR) has been shown to modify tobacco use in two independent Caucasian samples from the USA and Australia. Using information drawn from an eight-wave Australian population-based longitudinal study of adolescent health, we tested the effect of the HUMTH01-VNTR on nicotine dependence. Comparisons were made between dependent smokers and non-dependent smokers. These data provide further support for a protective association between the K4 allele and dependent smoking (odds ratio 0.54, 95% confidence interval 0.28-1.0). No associations were observed at any of three other common TH polymorphisms (rs6356, rs6357 and HUMTH01-PstI). Including these data, three independent studies, two of which use identical phenotypes, have now identified a protective relationship between the K4 allele of the functional HUMTH01-VNTR polymorphism and high-level smoking.

'Mother, teacher, adviser and missionary' : Matilda Ward in North Queensland, 1891–1917

This chapter focuses on Matilda Ward, a missionary at the Presbyterian mission of Mapoon, north Queensland, and the first paid woman missionary to work on an Aboriginal mission. It examines the factors that led to Ward’s employment on the mission, the role that she played in the life of the mission and the consequences of her actions for Indigenous mission residents. While Matilda Ward was unusual for her time, her experience points to broader shifts in missionary practice and attitudes to gender within the Australian churches, particularly through the development of women’s missionary societies.

A parent focused child obesity prevention intervention improves some mother obesity risk behaviors : the Melbourne infant program

Background

The diets, physical activity and sedentary behavior levels of both children and adults in Australia are suboptimal. The family environment, as the first ecological niche of children, exerts an important influence on the onset of children's habits. Parent modeling is one part of this environment and a logical focus for child obesity prevention initiatives. The focus on parent's own behaviors provides a potential opportunity to decrease obesity risk behaviors in parents as well.
Objective

To assess the effect of a parent-focused early childhood obesity prevention intervention on first-time mothers' diets, physical activity and TV viewing time.
Methods

The Melbourne InFANT Program is a cluster-randomized controlled trial which involved 542 mothers over their newborn's first 18 months of life. The intervention focused on parenting skills and strategies, including parental modeling, and aimed to promote development of healthy child and parent behaviors from birth, including healthy diet, increased physical activity and reduced TV viewing time. Data regarding mothers' diet (food frequency questionnaire), physical activity and TV viewing times (self-reported questionnaire) were collected using validated tools at both baseline and post-intervention. Four dietary patterns were derived at baseline using principal components analyses including frequencies of 55 food groups. Analysis of covariance was used to measure the impact of the intervention.
Results

The scores of both the "High-energy snack and processed foods" and the "High-fat foods" dietary patterns decreased more in the intervention group: -0.22 ([MINUS SIGN]0.42;-0.02) and [MINUS SIGN]0.25 ([MINUS SIGN]0.50;-0.01), respectively. No other significant intervention vs. control effects were observed regarding total physical activity, TV viewing time, and the two other dietary patterns, i.e. "Fruits and vegetables" and "Cereals and sweet foods".
Conclusions

These findings suggest that supporting first-time mothers to promote healthy lifestyle behaviors in their infants impacts maternal dietary intakes positively. Further research needs to assess ways in which we might further enhance those lifestyle behaviors not impacted by the InFANT intervention.

Mother-daughter communication about mammography in an Australian sample

Breast cancer is a significant health problem for aging women. Despite constant efforts to promote mammography in Australia to facilitate early detection, screening rates through the national mammography screening service remain at just 57%. Based on a theoretical rationale informed by Family Communication Patterns theory, the current study used semi-structured interviews with Australian mother-daughter dyads (N = 8) to examine their health communication, with a view to exploring the potential for daughters to deliver mammography promotion messages to their mothers. Consistent with results of previous studies conducted in different cultural contexts, the Australian mothers and daughters in this sample frequently communicated about health topics. Daughters were a source of information and influence for their mother's health decision making. The delivery of mammography promotion messages to the mother by the daughter may be most successful for dyads that value bidirectional conversation. Aspects of the Australian culture may facilitate the success of this strategy.

Conversations with my mother

An intense and sometimes disturbing series of encounters between the filmmaker and his mother as they relive the traumatic years of his childhood and adolescence. Following the migration of the family to Australia from Holland in the difficult postwar years they had to grapple with problems of housing, social injustice and adjustment made more difficult by the father's mental illness. For the filmmaker 'the sentiment had to be uncompromisingly true' although he became aware that 'all film is fiction'.

Unique IL-13Rα2-based HIV-1 vaccine strategy to enhance mucosal immunity, CD8(+) T-cell avidity and protective immunity.

We have established that mucosal immunization can generate high-avidity human immunodeficiency virus (HIV)- specific CD8þ T cells compared with systemic immunization, and interleukin (IL)-13 is detrimental to the functional avidity of these T cells. We have now constructed two unique recombinant HIV-1 vaccines that co-express soluble or membrane-bound forms of the IL-13 receptor a2 (IL-13Ra2), which can ‘‘transiently’’ block IL-13 activity at the vaccination site causing wild-type animals to behave similar to an IL-13 KO animal. Following intranasal/intramuscular prime-boost immunization, these IL-13Ra2-adjuvanted vaccines have shown to induce (i) enhanced HIV-specific CD8þ Tcells with higher functional avidity, with broader cytokine/chemokine profiles and greater protective immunity using a surrogate mucosal HIV-1 challenge, and also (ii) excellent multifunctional mucosal CD8þ T-cell responses, in the lung, genito-rectal nodes (GN), and Peyer’s patch (PP). Data revealed that intranasal delivery of these IL-13Ra2-adjuvanted HIV vaccines recruited large numbers of unique antigen-presenting cell subsets to the lung mucosae, ultimately promoting the induction of high-avidity CD8þ Tcells. We believe our novel IL-13R cytokine trap vaccine strategy offers great promise for not only HIV-1, but also as a platform technology against range of chronic infections that require strong sustained high-avidity mucosal/systemic immunity for protection.