Geographiske chartor öfwer Swerige med hans maj. konung Gustaf IV Adolphs allernådigste tillstånd utgifne af friherre S. G. Hermelin. [Kartta-aineisto] Andra Afdelningen, Storfurstendömet Finland.

Karttalehdet: Charta öfwer Swerige med tilgränsande länder ; Charta öfwer Storfurstendömet Finland ; Charta öfver Åbo och Björneborgs höfdingedöme ; Charta öfver Wasa höfdingedöme ; Charta öfver Uleåborgs höfdingedöme ; Charta öfver Savolax och Karelens eller Kuopio höfdingedöme ; Charta öfver Nylands och Tavastehus samt Kymmenegårds höfdingedömen. Nimiösivun kuva: Utsigt ifrån Wermasvuori åt sjöarne Jokijärvi och Ilmolanselkä uti Hauho sockn i Nylands och Tavastehus höfdingedöme / ritad af C. P. Hällström ; graverad af J. F. Martin.

Sec61alpha synthesis is enhanced during translocation of nascent chains of collagen type IV in F9 teratocarcinoma cells after retinoic acid treatment

Nascent procollagen peptides and other secretory proteins are transported across the endoplasmic reticulum (ER) membrane through a protein-conducting channel called translocon. Sec61alpha, a multispanning membrane translocon protein, has been implicated as being essential for translocation of polypeptide chains into the cisterns of the ER. Sec61alpha forms a protein complex with collagen and Hsp47, an ER-resident heat shock protein that binds specifically to collagen. However, it is not known whether Sec61alpha is ubiquitously produced in collagen-producing F9 teratocarcinoma cells or under heat shock treatment. Furthermore, the production and utilization of Sec61alpha may depend on the stage of cell differentiation. Cultured F9 teratocarcinoma cells are capable of differentiation in response to low concentrations of retinoic acid. This differentiation results in loss of tumorigenicity. Mouse F9 cells were grown in culture medium at 37ºC and 43ºC (heat shock treatment) treated or not with retinoic acid, and labeled in certain instances with 35S-methionine. Membrane-bound polysomes of procollagen IV were then isolated. Immunoprecipitation and Western blot analysis were performed using polyclonal antibodies against collagen IV, Hsp47 and Sec61alpha. Under retinoic acid-untreated conditions, F9 cells produced undetectable amounts of Sec61alpha. Sec61alpha, Hsp47 and type IV collagen levels were increased after retinoic acid treatment. Heat shock treatment did not alter Sec61alpha levels, suggesting that Sec61alpha production is probably not affected by heat shock. These data indicate that the enhanced production of Sec61alpha in retinoic acid-induced F9 teratocarcinoma cells parallels the increased synthesis of Hsp47 and collagen type IV.

Dipeptidyl peptidase IV (CD26) activity in the hematopoietic system: differences between the membrane-anchored and the released enzyme activity

Dipeptidyl peptidase IV (DPP-IV; CD26) (EC 3.4.14.5) is a membrane-anchored ectoenzyme with N-terminal exopeptidase activity that preferentially cleaves X-Pro-dipeptides. It can also be spontaneously released to act in the extracellular environment or associated with the extracellular matrix. Many hematopoietic cytokines and chemokines contain DPP-IV-susceptible N-terminal sequences. We monitored DPP-IV expression and activity in murine bone marrow and liver stroma cells which sustain hematopoiesis, myeloid precursors, skin fibroblasts, and myoblasts. RT-PCR analysis showed that all these cells produced mRNA for DPP-IV. Partially purified protein reacted with a commercial antibody to CD26. The K M values for Gly-Pro-p-nitroanilide ranged from 0.43 to 0.98 mM for the membrane-associated enzyme of connective tissue stromas, and from 6.76 to 8.86 mM for the enzyme released from the membrane, corresponding to a ten-fold difference, but only a two-fold difference in K M was found in myoblasts. K M of the released soluble enzyme decreased in the presence of glycosaminoglycans, nonsulfated polysaccharide polymers (0.8-10 µg/ml) or simple sugars (320-350 µg/ml). Purified membrane lipid rafts contained nearly 3/4 of the total cell enzyme activity, whose K M was three-fold decreased as compared to the total cell membrane pool, indicating that, in the hematopoietic environment, DPP-IV activity is essentially located in the lipid rafts. This is compatible with membrane-associated events and direct cell-cell interactions, whilst the long-range activity depending upon soluble enzyme is less probable in view of the low affinity of this form.

Purje-väylä kartta Saimaan vesillä Kiviluodosta Joensuuhun / valmistanut majori C. Lönneström vuonna 1864 ; uusi v. 1927 väylien suhteen korjattu painos.

1/35,700 osa luonnollisesta suuruudesta.

Charta öfver Uleåborgs höfdingedöme på friherre S. G. Hermelins anstalt och omkostnad författad enligt särskilde chartor och anmärkningar under resor af C. P. Hällström auscultant i Kongl. Bergs Colleg.

[1:750000].

Charta öfwer Storfurstendömet Finland utgifwen på friherre S. G. Hermelins anstalt och omkostnad Sammandragen och författad af C. P. Hällström philos. magister och auscultant i Kongl. Bergs Colleg.

[1:1620000].

Charta öfver Åbo och Björneborgs höfdingedöme utgifven af friherre S. G. Hermelin efter särskilde chartor författad af C. P. Hällström auscultant i Kl. Bergs Coll.

[1:540000].

Charta öfver Nylands och Tavastehus samt Kymmenegårds höfdingedömen utgifven af friherre S. G. Hermelin och författad af C. P. Hällström auscultant i Kl. Bergs Coll.

[1:540000].

Charta öfver Wasa höfdingedöme utgifven af friherre S. G. Hermelin författad af C. P. Hällström philos. mag. och ausc. vid auscultant i K. Bergs Coll.

[1:540000].

Charta öfver Savolax och Karelens eller Kuopio höfdingedöme utgifven af friherre S. G. Hermelin. Författad af C. P. Hällström.

[1:540000].

Theses, quas, cons. max. vener. facult. theol. in exercitationem stipendiariorum ad Academiam Imperialem Aboënsem, exhibet Henricus Snellman, theol. doct. [et] professor, Imper. Ord. de S. Wolod. in IV cl. eques, stipendiariorum h. a. inspector, respondente Claudio Alb. Tulindberg, stipend. publ. Ostrob. In auditorio philosophico die XII Junii MDCCCXXII. horis a. m. solitis

Painovuosi nimekkeestä.

Diálise peritoneal (DP) como tratamento da insuficiência cardíaca congestiva (ICC) em pacientes com doença renal crônica estágio IV

A Insuficiência Cardíaca Congestiva (ICC) é uma patologia com incidência crescente e que representa uma condição de grande impacto na saúde pública, com alta morbidade e mortalidade. O excesso de volume é uma complicação prevalente, presente em 80% dos pacientes atendidos com o diagnóstico de ICC. Estratégias farmacológicas e não farmacológicas no manejo terapêutico da ICC visam ao melhor manejo do volume e à redução no uso de diuréticos. A ultrafiltração extracorpórea tem evidenciado melhor controle de peso, redução nos dias de hospitalização e re-hospitalização dos pacientes com ICC. Neste artigo, relatamos dois casos atendidos no Hospital de Clínicas de Porto Alegre, relativos a pacientes com diagnóstico de ICC tratados com diálise peritoneal.