Guidance for laboratories performing molecular pathology for cancer patients

Molecular testing is becoming an important part of the diagnosis of any patient with cancer. The challenge to laboratories is to meet this need, using reliable methods and processes to ensure that patients receive a timely and accurate report on which their treatment will be based. The aim of this paper is to provide minimum requirements for the management of molecular pathology laboratories. This general guidance should be augmented by the specific guidance available for different tumour types and tests. Preanalytical considerations are important, and careful consideration of the way in which specimens are obtained and reach the laboratory is necessary. Sample receipt and handling follow standard operating procedures, but some alterations may be necessary if molecular testing is to be performed, for instance to control tissue fixation. DNA and RNA extraction can be standardised and should be checked for quality and quantity of output on a regular basis. The choice of analytical method(s) depends on clinical requirements, desired turnaround time, and expertise available. Internal quality control, regular internal audit of the whole testing process, laboratory accreditation, and continual participation in external quality assessment schemes are prerequisites for delivery of a reliable service. A molecular pathology report should accurately convey the information the clinician needs to treat the patient with sufficient information to allow for correct interpretation of the result. Molecular pathology is developing rapidly, and further detailed evidence-based recommendations are required for many of the topics covered here.

Unwilling Executioner:Crime Fiction and the State

What gives crime fiction its distinctive shape and form? What makes it such a compelling vehicle of social and political critique? Unwilling Executioner argues that the answer lies in the emerging genre's complex and intimate relationship with the bureaucratic state and modern capitalism, and the contradictions that ensue when the state assumes control of the justice system. This study offers a dramatic new interpretation of the genre's emergence and evolution over a three hundred year period and as a genuinely transnational phenomenon.

Globalization and the State in Contemporary Crime Fiction:A World of Crime

Why has crime fiction become a global genre? How do writers use crime fiction to reflect upon the changing nature of crime and policing in our contemporary world? This book argues that the globalization of crime fiction should not be celebrated uncritically. Instead, it looks at the new forms and techniques writers are using to examine the crimes and policing practices that define a rapidly changing world. In doing so, this collection of essays examines how the relationship between global crime, capitalism, and policing produces new configurations of violence in crime fiction – and asks whether the genre can find ways of analyzing and even opposing such violence as part of its necessarily limited search for justice both within and beyond the state.

1992 CRIME IN SOUTH CAROLINA

The South Carolina State Law Enforcement Division publishes Crime in South Carolina, an annual report that provides general information about crime trends, provides crime data at the county level for the most recent year available, compares national and state crime trends and provides descriptive information about crime.

1993 CRIME IN SOUTH CAROLINA

The South Carolina State Law Enforcement Division publishes Crime in South Carolina, an annual report that provides general information about crime trends, provides crime data at the county level for the most recent year available, compares national and state crime trends and provides descriptive information about crime.

1994 CRIME IN SOUTH CAROLINA

The South Carolina State Law Enforcement Division publishes Crime in South Carolina, an annual report that provides general information about crime trends, provides crime data at the county level for the most recent year available, compares national and state crime trends and provides descriptive information about crime.

CRIME IN SOUTH CAROLINA 1996

The South Carolina State Law Enforcement Division publishes Crime in South Carolina, an annual report that provides general information about crime trends, provides crime data at the county level for the most recent year available, compares national and state crime trends and provides descriptive information about crime.

CRIME IN SOUTH CAROLINA 1997

The South Carolina State Law Enforcement Division publishes Crime in South Carolina, an annual report that provides general information about crime trends, provides crime data at the county level for the most recent year available, compares national and state crime trends and provides descriptive information about crime.