820 resultados para Conceções Alternativas


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This study discuss the use of the geotechnologies to aid the planners on the terrain aptness definition for highways implantation and on the different trace evaluation to the extention of the Governador Carvalho Pinto highway, between Taubaté-SP and Aparecida do Norte-SP. Fratures on the area were mapping using Landsat ETM+, band Pan. In order to elaborate the phisical aptness chart for highway implantation was used the Analitical Hierarchy Process (AHP) operation, in on geographical information system (GIS). Using GIS were realized a ponderate middle with the soils, rocks, relief, slope, fractures and land use/cover maps. Using this physical aptness chart and joinning it with urban and restrict areas (that was inserted by the Boolean operation), were obtained a viability chart for highway implantation. Based on it were proposed three aleatory traces for the Carvalho Pinto highway. This traces were evaluated with the cross tabulation operation. The integration of the restrict areas, land use and phisical aptness in digital media can offer for the planners the cartography of the viability for the highway implantation. The evaliation of these three traces, based on the viability chart, can subsidyse the decision by the planners.

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Partial outcomes of a study aimed to verify future High School teachers performance during the development of a Teaching Practice undergraduate course. The student teachers were asked to plan, elaborate and teach, in a classroom situation, optics topics to a class which included visual handicapped pupils. Data analysis shows that the main difficulties found by the student physics' teachers are related to which approach will be used to perceive phenomena dependent on vision and also to the need to break away from traditional pedagogy.. On the other hand, as alternatives, future teachers have shown creativity in order to overcome passive aptitudes related to this educational problem, working out methodological strategies that do not require the knowing/seeing relation, as well as, emphasizing oral communication within the physics teaching context. Copyright by the Sociedade Brasileira de Física.

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Incluye Bibliografía

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Praziquantel (PZQ) is the drug of choice commonly used for the treatment of shistosomiasis. However, it has low aqueous solubility, which could limit its bioavailability in the body. To circumvent these features, an inclusion complex with hydroxypropyl-beta- cyclodextrin (HP-β-CD) was prepared. Thus, the objective of this work was to prepare and characterize the PZQ/HP-β-CD inclusion complex. Morphological, spectroscopic, and calorimetric analysis showed the first signs of the guest/host interaction. The complexation kinetic analysis was used to determine the kinetic constant and, besides that, it was possible to establish the time consumed to reach equilibrium. Using the solubility isotherm, it was observed that the interaction with HP-β-CD increased 2.4 fold the aqueous solubility of plain PZQ. In vitro cytotoxicity tests, using fibroblast cells, evidenced no toxicity for these cells at the concentrations tested. These results demonstrated that there is a potential use of PZQ in formulations with HP-β-CD.