UTILIZAÇÃO TECNOLÓGICA DOS FRUTOS DE JATOBÁ-DO-CERRADO E DE JATOBÁ-DA-MATA NA ELABORAÇÃO DE BISCOITOS FONTES DE FIBRA ALIMENTAR E ISENTOS DE AÇÚCARES

Este trabalho teve como objetivo investigar a aplicação das farinhas de jatobá-do-cerrado (Hymenaea stigonocarpa Mart.) e jatobá-da-mata (Hymenaea stilbocarpa Mart.) adicionadas à farinha de trigo na elaboração de biscoitos fontes de fibra alimentar e isentos de açúcares. A composição centesimal das farinhas de jatobá foi determinada, e posteriormente, foram elaborados biscoitos com substituição de 10, 15, 20 e 25% da farinha de trigo pelas farinhas de jatobá das duas espécies. Os biscoitos foram avaliados nas suas características físicas, químicas e sensoriais. As farinhas de jatobá-do-cerrado e de jatobá-da-mata apresentaram, em base seca, teores de proteína bruta de 7,60±0,22 e 8,37±0,12g/100g, lipídios de 3,03±0,05 e 2,92±0,11g/100g, cinzas de 4,60±0,06 e 5,48±0,07, fibra alimentar solúvel de 11,01±0,50 e 9,81±0,58g/100g, fibra alimentar insolúvel de 42,86±0,27 e 45,79±0,61g/100g e carboidratos de 18,54±0,55 e 20,18± 0,46g/100g, respectivamente. O fator de expansão foi maior nos biscoitos elaborados com farinha de jatobá-do-cerrado nos níveis 20 e 25% de substituição e nos biscoitos contendo 15 e 25% de farinha de jatobá-da-mata. Os biscoitos com substituição de 10% das farinhas de jatobá foram os que apresentaram maior nível de aceitação, não diferindo significativamente (p<0,05), quanto aos escores para degustação e aparência. Os biscoitos elaborados com 10% de farinha de jatobá-do-cerrado e de jatobá-da-mata apresentaram teor de fibra alimentar total de 6,05±0,09 e 6,77±0,53g/100g, respectivamente. Biscoitos isentos de açúcares e fontes de fibra alimentar podem ser produzidos com a substituição de 10% de farinha de trigo pelas farinhas de jatobá.

Immunosupressive therapy in children with steroid-resistant nephrotic syndrome: single center experience

INTODUCTION: Nephrotic syndrome is one of the most frequent glomerular diseases among children, and steroid therapy remains as the treatment choice. In spite of this, 10 to 15% of the patients are steroidresistant, and the best therapy for such cases has never been defined. Mycophenolate acid (MA) is one of the treatments used in such situations. OBJECTIVE: To describe the clinical behavior of children diagnosed with steroid-resistant nephrotic syndrome (SRNS) and to assess the therapeutic response to MA. METHODS: This was a retrospective and descriptive study. RESULTS: 26 clinical records of patients with SRNS; 70% male and 30% female. All patients underwent kidney biopsies, which showed a predominance of focal segmental glomerulosclerosis (FSGS). The immunosuppresive drugs used were: Mycophenolate mofetil (MMF) 100%, Cyclosporine 69.2%, Cyclophosphamide 23.1%, and Rituximab 23%. One month after treatment initiation with MMF 61.5% achieved remission. The median of relapses per year for the patients was 3 (p25: 2.75 - p75: 4). This median became 1 (p25: 1 - p75: 3.25) after using this medication (p = 0.08). Furthermore, prior to the start of the MMF treatment, the median of the steroid dose was 1 (p25: 0.5- p75: 1.62) mg/k/day. After using MMF, this median became 0.07 (p25: 0 - p75: 0.55) mg/k/day (p < 0.001), in 8 patients prednisolone was stopped. CONCLUSION: In our experience, treatment with MMF showed positive results such as decrease in the frequency of relapses, less proteinuria, and reduction in the dose of steroids administered without deterioration of glomerular filtration rates. However, more studies are needed to assess efficacy, safety, and optimal dosage.

L'Écho de Paris

1886/07/21 (Numéro 860).

25/07/20, Tour de France, arrivée de [Jean] Rossius, gagnant de la dernière étape : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 60204

25/07/20, [hippodrome d'Auteuil, allocution du général de Maud'huy et fanfare de la] fête des chasseurs : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 60209

25/07/20, fête des chasseurs [peloton cycliste de militaires, hippodrome d'Auteuil] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 60212

31-07-20, Paris à la mer, les concurrents dans l'écluse de Murreux : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 60275

31-07-20, Paris à la mer, glisseur Farman : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 60281

Parc des Princes, 25/07/20, [Honoré] Barthélémy [8e et premier Français du Tour de France 1920] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 60202

25/07/20, Tour de France, [Philippe] Thys, gagnant : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 60202 bis

25/07/20, Tour de France, [Jean] Rossius, gagnant de la dernière étape : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 60203

25/07/20, [hippodrome d'Auteuil, fête des chasseurs à pied, promenade de] la mascotte des chasseurs [par un clown nain] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 60207

25/07/20, [hippodrome d'Auteuil, fête des chasseurs à pied, promenade de] la mascotte des chasseurs [par un clown nain] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 60208