1000 resultados para 270
Resumo:
A reforma orçamental nesta fase de viragem das Finanças Públicas Cabo –Verdiana , onde a transparência e a boa governação são palavras de ordem, num País ainda dependente da ajuda externa no seu processo de desenvolvimento, há necessidade efectiva de se apostar na melhoria da qualidade da despesa pública como condição sine qua non para se atingir a almejada economicidade, eficiência e eficácia na gestão da coisa pública. Neste processo, o orçamento enquanto instrumento de política ganha importância capital, particularmente na vertente de despesa. O trabalho faz uma abordagem histórica da reforma orçamental na sua vertente de despesa, analisa a suas implicações e propõe um novo instrumento de qualificação da despesa pública em Cabo Verde.
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Kirje
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A large body of published work shows that proton (hydrogen 1 [(1)H]) magnetic resonance (MR) spectroscopy has evolved from a research tool into a clinical neuroimaging modality. Herein, the authors present a summary of brain disorders in which MR spectroscopy has an impact on patient management, together with a critical consideration of common data acquisition and processing procedures. The article documents the impact of (1)H MR spectroscopy in the clinical evaluation of disorders of the central nervous system. The clinical usefulness of (1)H MR spectroscopy has been established for brain neoplasms, neonatal and pediatric disorders (hypoxia-ischemia, inherited metabolic diseases, and traumatic brain injury), demyelinating disorders, and infectious brain lesions. The growing list of disorders for which (1)H MR spectroscopy may contribute to patient management extends to neurodegenerative diseases, epilepsy, and stroke. To facilitate expanded clinical acceptance and standardization of MR spectroscopy methodology, guidelines are provided for data acquisition and analysis, quality assessment, and interpretation. Finally, the authors offer recommendations to expedite the use of robust MR spectroscopy methodology in the clinical setting, including incorporation of technical advances on clinical units. © RSNA, 2014 Online supplemental material is available for this article.
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Kirje 3.7.1940
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Chronic-inflammatory demyelinating polyneuropathy (CIDP) is an immune-mediated disease with no known biomarkers for diagnosing the disease or assessing its prognosis. We performed transcriptional profiling microarray analysis on skin punch biopsies from 20 CIDP patients and 17 healthy controls to identify disease-associated gene expression changes. We demonstrate changes in expression of genes involved in immune and chemokine regulation, growth and repair. We also found a combination of two upregulated genes that can be proposed as a novel biomarker of the disorder.
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Describe tres especies nuevas para la ciencia: mustelus whitneyi, raja velezi y schedophilus haedrichi de la costa peruana. El material examinado proviene de las exploraciones pesqueras que periódicamente realiza el Instituto del mar del Perú a lo largo y frente a nuestro litoral, sobre la plataforma y talud continental, además de algunas embarcaciones comerciales y laboratorios costeros de IMARPE.
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Puhe
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Biodiversity within the subfamily Alyssinae (Hymenoptera, Braconidae) in the Natural Park Peñas de Aya (Spain). The study of parasitoid Hymenoptera is of significance for the assessment of diversity in a given area because of their role in the regulation of insects populations. The present work analyses diversity within Alysiinae (Hymenoptera, Braconidae) in the Forested Estate of Artikutza, located in the Natural Park Peñas de Aya, western Pyrenees, Spain. Collection of specimens was spread over two years and was carried out in two different habitats: mixed forest and beech forest. A total of 2,270 specimens, belonging to 22 separate genera, were captured. Subsequently, alpha, beta and gamma diversities were analysed, and the beech forest was proven to host greater diversity than the mixed forest. A sampling strategy was adopted for the analysis of Alysiinae phenology and its relationship with environmental climatic conditions; as a result, a direct relationship between phenology and temperature was attested.