Regulation of phyllotaxis by polar auxin transport

The regular arrangement of leaves around a plant's stem, called phyllotaxis, has for centuries attracted the attention of philosophers, mathematicians and natural scientists; however, to date, studies of phyllotaxis have been largely theoretical. Leaves and flowers are formed from the shoot apical meristem, triggered by the plant hormone auxin. Auxin is transported through plant tissues by specific cellular influx and efflux carrier proteins. Here we show that proteins involved in auxin transport regulate phyllotaxis. Our data indicate that auxin is transported upwards into the meristem through the epidermis and the outermost meristem cell layer. Existing leaf primordia act as sinks, redistributing auxin and creating its heterogeneous distribution in the meristem. Auxin accumulation occurs only at certain minimal distances from existing primordia, defining the position of future primordia. This model for phyllotaxis accounts for its reiterative nature, as well as its regularity and stability.

On the Limits of Greenwich Mean Time, or The Failure of a Modernist Revolution

On the Limits of Greenwich Mean Time, or The Failure of a Modernist Revolution From the introduction of World Standard Time in 1884 to Einstein’s theory of relativity, the nature and regulation of time was a highly contested issue in modernism, with profound political, social and epistemological consequences. Modernist aesthetic sensibilities widely revolted against the increasingly strict rule of the clock, which, as Georg Simmel observed in “The Metropolis and Mental Life,” was established as the necessary basis of a capitalist, urban life. This paper will focus on the contending conceptions of time arising in key modernist texts by authors like Joyce, Woolf and Conrad. I will argue that the uniformity and regularity of time necessary to a rising capitalist society came under attack in a similar way by both modernist literary aesthetics and new scientific discoveries. However, while Einstein’s theory of relativity may have led to a subsequent change of paradigm in scientific thought, it has failed to significantly alter social and popular conceptions of time. Although alternative ways of thinking and living with time are proposed by modernist authors, they remain isolated aesthetic experiments, ineffectual against the regulatory pressure of economic and social structures. In this struggle about the nature of time, so I suggest, science and literature join force against a society that is increasingly governed by economic reason. The fact that they lost this struggle can serve as a striking illustration of an increasing shift of social influence from science and art towards economy.

Kinetics and kinematics of the tölt: effects of rider interaction and shoeing manipulations

Introduction . Compared to most equine horse breeds which are able to walk, trot and canter /gallop, the gait repertoire of the Icelandic horses additionally includes the lateral gait tölt and frequently also the pace. With respect to the tölt gait, special shoeing, saddling and riding techniques have been developed for Icelandic horses in order to enhance its expressiveness and regularity. Toes are left unnaturally long and heavy shoes and paddings, as well as weighted boots are used to enforce the individual gait predisposition. For the same reason, the rider is placed more caudally to the horse's centre of mass as compared to other riding techniques. The biomechanical impact of these methods on the health of the locomotor system has so far never been subject of systematic research. Objectives . The aims of the presented study are (1) to describe the kinetic and kinematic characteristics of the tölt performed on a treadmill, (2) to understand the mechanical consequences of shoeing manipulation (long hooves, weighted boots) on the loading and protraction movement of the limbs, as well as (3) to study the pressure distribution and effects on the gait pattern of 3 different saddle types used for riding Icelandic horses. Materials and methods . Gait analysis was carried out in 13 Icelandic horses at walk and at slow and medium tölting and trotting speeds on a high-speed treadmill instrumented for measuring vertical ground reaction forces as well as temporal and spatial gait variables. Kinematic data of horse, rider and saddle were measured simultaneously. Gait analysis was first carried out with high, long hooves (SH) without and in combination with weighted boots (ad aim (2)). Afterwards, horses were re-shod according to current horseshoeing standards (SN) and gait analysis was repeated (ad aims (1) and (2)). In a second trial, horses were additionally equipped with a pressure sensitive saddle mat and were ridden with a dressage-like saddle (SDres), an Icelandic saddle (Slcel) and a saddle cushion (SCush) in the standard saddle position (ad aim 3). Results and conclusions . Compared to trot at the same speed, tölting horses had a higher stride rate and lower stride impulses. At the tölt loading of the forelimbs was increased in form of higher peak vertical forces (Fzpeak) due to shorter relative stance durations (StDrel). Conversely, in the hindlimbs, longer StDrel resulted in lower Fzpeak. Despite the higher head-neck position at tölt, there was no measurable shift in weight to the hindlimbs. Footfall rhythm was in most horses laterally coupled at the tölt and frequently had a slight fourbeat and a very short suspension phase at trot; underlining the fact that performance of correct gaits in Icelandic horses needs special training. Gait performance as it is currently judged in competition could be improved using a shoeing with SH, resulting in a 21 ± 5 mm longer dorsal hoof wall, but also a weight gain of 273 ± 50 g at the distal limb due to heavier shoeing material. Compared to SN, SH led to a lower stride rate, a longer stride length and a higher, but not wider, forelimb protraction arc, which were also positively associated with speed. At the tölt, the footfall rhythm showed less tendency to lateral couplets and at the trot, the suspension phase was longer. However, on the long term, SH may have negative implications for the health of the palmar structures of the distal foot by increased limb impulses, higher torques at breakover (up to 20%); as well as peak vertical forces at faster speeds. Compared to the shoeing style, the saddle type had less influence on limb forces or movements. The slight weight shift to the rear with SCush and Slcel may be explained by the more caudal position of the rider relative to the horse's back. With SCush, pressure was highest under the cranial part of the saddle, whereas the saddles with trees had more pressure under the caudal area.

Pattern and process: competition causes regular spacing of individuals within plant populations

1 We used simulated and experimental plant populations to analyse mortality-driven pattern formation under size-dependent competition. Larger plants had an advantage under size-asymmetric but not under symmetric competition. Initial patterns were random or clumped. 2 The simulations were individual-based and spatially explicit. Size-dependent competition was modelled with different rules to partition overlapping zones of influence. 3 The experiment used genotypes of Arabidopsis thaliana with different morphological plasticity and hence size-dependent competition. Compared with wild types, transgenic individuals over-expressed phytochrome A and had decreased plasticity because of disabled phytochrome-mediated shade avoidance. Therefore, competition among transgenics was more asymmetric compared with wild-types. 4 Density-dependent mortality under symmetric competition did not substantially change the initial spatial pattern. Conversely, simulations under asymmetric competition and experimental patterns of transgenic over-expressors showed patterns of survivors that deviated substantially from random mortality independent of initial patterns. 5 Small-scale initial patterns of wild types were regular rather than random or clumped. We hypothesize that this small-scale regularity may be explained by early shade avoidance of seedlings in their cotyledon stage. 6 Our experimental results support predictions from an individual-based simulation model and support the conclusion that regular spatial patterns of surviving individuals should be interpreted as evidence for strong, asymmetric competitive interactions and subsequent density-dependent mortality.

Regulation of phyllotaxis

Plant architecture is characterized by a high degree of regularity. Leaves, flowers and floral organs are arranged in regular patterns, a phenomenon referred to as phyllotaxis. Regular phyllotaxis is found in virtually all higher plants, from mosses, over ferns, to gymnosperms and angiosperms. Due to its remarkable precision, its beauty and its accessibility, phyllotaxis has for centuries been the object of admiration and scientific examination. There have been numerous hypotheses to explain the nature of the mechanistic principle behind phyllotaxis, however, not all of them have been amenable to experimental examination. This is due mainly to the delicacy and small size of the shoot apical meristem, where plant organs are formed and the phyllotactic patterns are laid down. Recently, the combination of genetics, molecular tools and micromanipulation has resulted in the identification of auxin as a central player in organ formation and positioning. This paper discusses some aspects of phyllotactic patterns found in nature and summarizes our current understanding of the regulatory mechanism behind phyllotaxis.

hp-DGFEM for second-order mixed elliptic problems polyhedra

We prove exponential rates of convergence of hp-version discontinuous Galerkin (dG) interior penalty finite element methods for second-order elliptic problems with mixed Dirichlet-Neumann boundary conditions in axiparallel polyhedra. The dG discretizations are based on axiparallel, σ-geometric anisotropic meshes of mapped hexahedra and anisotropic polynomial degree distributions of μ-bounded variation. We consider piecewise analytic solutions which belong to a larger analytic class than those for the pure Dirichlet problem considered in [11, 12]. For such solutions, we establish the exponential convergence of a nonconforming dG interpolant given by local L 2 -projections on elements away from corners and edges, and by suitable local low-order quasi-interpolants on elements at corners and edges. Due to the appearance of non-homogeneous, weighted norms in the analytic regularity class, new arguments are introduced to bound the dG consistency errors in elements abutting on Neumann edges. The non-homogeneous norms also entail some crucial modifications of the stability and quasi-optimality proofs, as well as of the analysis for the anisotropic interpolation operators. The exponential convergence bounds for the dG interpolant constructed in this paper generalize the results of [11, 12] for the pure Dirichlet case.

A role for tuned levels of nucleosome remodeler subunit ACF1 during Drosophila oogenesis

The Chromatin Accessibility Complex (CHRAC) consists of the ATPase ISWI, the large ACF1 subunit and a pair of small histone-like proteins, CHRAC-14/16. CHRAC is a prototypical nucleosome sliding factor that mobilizes nucleosomes to improve the regularity and integrity of the chromatin fiber. This may facilitate the formation of repressive chromatin. Expression of the signature subunit ACF1 is restricted during embryonic development, but remains high in primordial germ cells. Therefore, we explored roles for ACF1 during Drosophila oogenesis. ACF1 is expressed in somatic and germline cells, with notable enrichment in germline stem cells and oocytes. The asymmetrical localization of ACF1 to these cells depends on the transport of the Acf1 mRNA by the Bicaudal-D/Egalitarian complex. Loss of ACF1 function in the novel Acf1(7) allele leads to defective egg chambers and their elimination through apoptosis. In addition, we find a variety of unusual 16-cell cyst packaging phenotypes in the previously known Acf1(1) allele, with a striking prevalence of egg chambers with two functional oocytes at opposite poles. Surprisingly, we found that the Acf1(1) deletion - despite disruption of the Acf1 reading frame - expresses low levels of a PHD-bromodomain module from the C-terminus of ACF1 that becomes enriched in oocytes. Expression of this module from the Acf1 genomic locus leads to packaging defects in the absence of functional ACF1, suggesting competitive interactions with unknown target molecules. Remarkably, a two-fold overexpression of CHRAC (ACF1 and CHRAC-16) leads to increased apoptosis and packaging defects. Evidently, finely tuned CHRAC levels are required for proper oogenesis.

Contribution of activity and skin temperature to the risk of developing pressure ulcers in nursing facility residents

Purpose. The central concepts in pressure ulcer risk are exposure to external pressure caused by inactivity and tissue tolerance to pressure, a factor closely related to blood flow. Inactivity measures are effective in predicting pressure ulcer risk. The purpose of the study is to evaluate whether a physiological measure of skin blood flow improves pressure ulcer risk prediction. Skin temperature regularity and self-similarity, as proxy measures of blood flow, and not previously described, may be undefined pressure ulcer risk factors. The specific aims were to determine whether a sample of nursing facility residents at high risk of pressure ulcers classified using the Braden Scale for Pressure Sore Risk© differ from a sample of low risk residents according to (1) exposure to external pressure as measured by resident activity, (2) tissue tolerance to external pressure as measured by skin temperature, and (3) skin temperature fluctuations and recovery in response to a commonly occurring stressor, bathing and additionally whether (4) scores on the Braden Scale mobility subscale score are related to entropy and the spectral exponent. ^ Methods. A two group observational time series design was used to describe activity and skin temperature regularity and self-similarity, calculating entropy and the spectral exponent using detrended fluctuation analysis respectively. Twenty nursing facility residents wore activity and skin temperature monitors for one week. One bathing episode was observed as a commonly occurring stressor for skin temperature.^ Results. Skin temperature multiscale entropy (MSE), F(1, 17) = 5.55, p = .031, the skin temperature spectral exponent, F(1, 17) = 6.19, p = .023, and the activity mean MSE, F(1, 18) = 4.52, p = .048 differentiated the risk groups. The change in skin temperature entropy during bathing was significant, t(16) = 2.55, p = .021, (95% CI, .04-.40). Multiscale entropy for skin temperature was lowest in those who developed pressure ulcers, F(1, 18) = 35.14, p < .001.^ Conclusions. This study supports the tissue tolerance component of the Braden and Bergstrom conceptual framework and shows differences in skin temperature multiscale entropy between pressure ulcer risk categories, pressure ulcer outcome, and during a commonly occurring stressor. ^

Alberto Magno y la revisión de la teoría hilemórfica de Aristóteles

La doctrina hilemórfica de la materia como pura potencia y la forma como acto parece no satisfacer al dominico Alberto Magno, pues le resulta insuficiente para explicar los procesos naturales. Por esto, redefine los principios metafísicos fundamentales del aristotelismo, y asimismo expone nuevos principios constitutivos de la realidad, bajo inspiración de la filosofía neoplatónica y del pensamiento árabe. Así, Alberto sostiene que la materia prima debe ser entendida como una suerte de realidad actualizada, compuesta por diversas formas incoadas previamente al advenimiento de la forma sustancial. La incohatio formae, según el dominico, dispone a la materia a recibir cierta forma en vez de otra en la futura generación, lo cual justifica la regularidad de todo proceso natural. La materia primera, entonces, no participa meramente como sustrato del cambio sustancial y no puede ser definida como una realidad completamente simple. Por sí misma, posee un esse materiae y constituye una entidad substancial, la materia posee un ser independiente de la forma, al igual que la forma es independiente de la materia. En los tratados de la Physica y Metaphysica, Alberto Magno desarrolla una doctrina propia, aunque claramente influenciada por la cosmología y metafísica averroísta.

Argumentación, desplazamientos semánticos e imaginario cultural en Heródoto IX. 26-27

A partir de estrategias de análisis del discurso, el trabajo analiza la disputa erística que, según Heródoto, acaeció entre tegeatas y atenienses en las vísperas de la batalla de Platea (Hdt. IX. 26-7). Entendemos que la presunta simetría y regularidad en los dichos y contenidos de ambos discursos es en rigor engañosa en tanto que enmascara la contraposición de dos imaginarios culturales, representados por tegeatas y atenienses respectivamente. Dicho antagonismo se evidencia en un sutil proceso de desplazamientos semánticos por medio de los cuales Heródoto caracteriza de manera singular una y otra comunidad y el basamento ideológico-político sobre el que se sustentan.

La dinámica mercantil de las mujeres rioplatenses frente al resquebrajamiento del Antiguo Régimen (1806-1810)

Este trabajo tiene como objetivo analizar la dinámica mercantil de las mujeres rioplatenses en el marco de los acontecimientos que se suscitaron entre 1806 y 1810. Explorar la mecánica de los comportamientos previos a esa etapa resulta fundamental para observar los cambios que se produjeron después. A fin de examinar tales cambios se recurre a una serie de variables: las formas de participación en la práctica mercantil, esto es, si cargaban los frutos y efectos a su cuenta y riesgo, y/o a través de terceros o experimentaban con las dos modalidades, el grado de inserción y permanencia en la actividad para definirlas en función de la mayor o menor regularidad en el ejercicio comercial, los rubros comercializados y la relación con las rutas del intercambio oceánico y regional

Las revistas académicas del campo de la educación (Argentina, 1990-2002)

El estudio de las revistas especializadas permite comprender aspectos importantes de la dinámica de los campos científicos y académicos. Entre ellos, los grados de institucionalización, diferenciación y especialización o las redes de intercambio. La cantidad, la calidad y la difusión de las revistas expresa, en buena medida, el poder relativo de las diversas comunidades académicas y su influencia en el nivel nacional e internacional. Este estudio realiza un análisis descriptivo de las revistas académicas argentinas especializadas en educación durante la década de 1990, como parte de una investigación más amplia sobre la producción de conocimientos en educación, desarrollada en la FLACSO entre 2002 y 2004. Se presentan los datos y conclusiones del análisis de 17 revistas que refieren exclusivamente a temas de educación y que declaran contar con algún mecanismo de referato científico-académico. La descripción toma como punto de partida las siguientes dimensiones: a) las agencias productoras; b) las referencias temporales (fecha de aparición, frecuencia y regularidad de las revistas); c) la distribución regional; d) la estructura de las publicaciones; d) la pertenencia institucional de los autores y e) los temas abordados en las publicaciones. Al final del artículo, se discuten los avances alcanzados en materia de publicaciones en la década pasada y las dificultades que persisten para consolidar una cantidad y diversidad de instancias de comunicación especializada en el campo de la educación en la Argentina.

El potencial de la agricultura familiar y los espacios protegidos : Lineamientos para el diseño de políticas públicas

Hay una cantidad de explotaciones familiares que aún perduran y se resisten a desaparecer, desplegando variadas y novedosas estrategias productivas, sociales y culturales. Precisamente, el objetivo de este artículo es presentar dos casos de explotaciones familiares en contextos muy diferentes: una ubicada en el Dpto. Banda de la provincia de Santiago del Estero y la otra en el Partido de Saladillo, provincia de Buenos Aires, donde la diversidad y regularidad de las estrategias adoptadas les han permitido persistir y desarrollar estrategias alternativas al modelo vigente. El despliegue del potencial productivo, ecológico y social de la agricultura familiar requiere de la construcción de espacios protegidos. Así, los espacios protegidos se presentan como un argumento sobre la potencialidad de la agricultura familiar y su capacidad de generar un desarrollo rural alternativo, en el que la pequeña producción tenga un rol activo en la construcción de este nuevo diseño. No obstante, en la actualidad, los espacios protegidos no son más que una hipótesis y una declaración de las posibilidades sobre la forma en la que el mundo agrario podría estructurarse con base en la pequeña producción. La sistematización de los casos comienza a mostrar caminos y pautas posibles de aprendizajes para esa construcción

La dinámica mercantil de las mujeres rioplatenses frente al resquebrajamiento del Antiguo Régimen (1806-1810)

Este trabajo tiene como objetivo analizar la dinámica mercantil de las mujeres rioplatenses en el marco de los acontecimientos que se suscitaron entre 1806 y 1810. Explorar la mecánica de los comportamientos previos a esa etapa resulta fundamental para observar los cambios que se produjeron después. A fin de examinar tales cambios se recurre a una serie de variables: las formas de participación en la práctica mercantil, esto es, si cargaban los frutos y efectos a su cuenta y riesgo, y/o a través de terceros o experimentaban con las dos modalidades, el grado de inserción y permanencia en la actividad para definirlas en función de la mayor o menor regularidad en el ejercicio comercial, los rubros comercializados y la relación con las rutas del intercambio oceánico y regional

Las revistas académicas del campo de la educación (Argentina, 1990-2002)

El estudio de las revistas especializadas permite comprender aspectos importantes de la dinámica de los campos científicos y académicos. Entre ellos, los grados de institucionalización, diferenciación y especialización o las redes de intercambio. La cantidad, la calidad y la difusión de las revistas expresa, en buena medida, el poder relativo de las diversas comunidades académicas y su influencia en el nivel nacional e internacional. Este estudio realiza un análisis descriptivo de las revistas académicas argentinas especializadas en educación durante la década de 1990, como parte de una investigación más amplia sobre la producción de conocimientos en educación, desarrollada en la FLACSO entre 2002 y 2004. Se presentan los datos y conclusiones del análisis de 17 revistas que refieren exclusivamente a temas de educación y que declaran contar con algún mecanismo de referato científico-académico. La descripción toma como punto de partida las siguientes dimensiones: a) las agencias productoras; b) las referencias temporales (fecha de aparición, frecuencia y regularidad de las revistas); c) la distribución regional; d) la estructura de las publicaciones; d) la pertenencia institucional de los autores y e) los temas abordados en las publicaciones. Al final del artículo, se discuten los avances alcanzados en materia de publicaciones en la década pasada y las dificultades que persisten para consolidar una cantidad y diversidad de instancias de comunicación especializada en el campo de la educación en la Argentina.