940 resultados para quality function development


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This contribution focuses on analyzing the quality of democracy of the United States (U.S.) and of Austria by using a comparative approach. Even though comparisons are not the only possible or legitimate method of research, this analysis is based on the opinion that comparisons provide crucial analytical perspectives and learning opportunities. Following is the proposition, put directly forward: national political systems (political systems) are comprehensively understood only by using an international comparative approach. International comparisons (of country-based systems) are common (see the status of comparative politics, for example in Sodaro, 2004). Comparisons do not have to be based necessarily on national systems alone, but can also be carried out using “within”-comparisons inside (or beyond) sub-units or regional sub-national systems, for instance the individual provinces in the case of Austria (Campbell, 2007, p. 382).

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Mechanotransduction refers to the conversion of mechanical forces into biochemical or electrical signals that initiate structural and functional remodeling in cells and tissues. The heart is a kinetic organ whose form changes considerably during development and disease. This requires cardiomyocytes to be mechanically durable and able to mount coordinated responses to a variety of environmental signals on different time scales, including cardiac pressure loading and electrical and hemodynamic forces. During physiological growth, myocytes, endocardial and epicardial cells have to adaptively remodel to these mechanical forces. Here we review some of the recent advances in the understanding of how mechanical forces influence cardiac development, with a focus on fluid flow forces. This article is part of a Special Issue entitled: Cardiomyocyte Biology: Integration of Develomental and Environmental Cues in the Heart edited by Marcus Schaub and Hughes Abriel.

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Mode of access: Internet.

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Transportation Department, Research and Special Programs Directorate, Washington, D.C.

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Transportation Department, Research and Special Programs Directorate, Washington, D.C.

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National Highway Traffic Safety Administration, Office of Driver and Pedestrian Research, Washington, D.C.

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Symposium organized by the Office of Health Affairs, Food and Drug Administration.