831 resultados para eventos adversos


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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Pós-graduação em Geografia - IGCE

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Atherosclerosis is a chronic inflammatory disease characterized by accumulation of lipid and fibrous components in arterial vessels, giving rise to atheromas. Development of Atheromatou plaques leads to arterial steatosis, triggering ischemic events. Atherotrombosis has a strong correlation with atherosclerosis, where rupture of atheromatous plaques cause release of vessel wall's pro-thrombotic components, activating platelet aggregation and thromosis. Due to the major role played by platelets on thrombus-embolic conditions, drugs that inhibit platelet aggregation demonstrate great relevance for atherothrombosis prevention, reducing patient mortality. Currently, there are a variety of drugs acting on several different targets, preventing platelet activation. However, these therapies demosntrate side effects such as thrombocytopenia, neutropenia, hemorrhage and low oral availability. Thus, the application of molecular modifications such as hybridization can produce novel, more efficient antiplatelet aggregation inhibitors. In this project we describe the synthesis and characterization of novel N-acilhydrazone compounds, acting through multiple mechanisms such as platelet calcium chelation and nitric oxide donation by furoxanic subunits. Furthermore, we demonstrate that such compounds exhibit biological activity in in vivo bleeding time, in vitro antiplatelet aggregation and in vivo antinociceptive assays. Therefore, novel N-acilhydrazone compounds demonstrate potential as antiplatelet drugs for atherothrombosis prevention.

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The Micro and Small Enterprises are in a special group of companies it given potential for development, employability, and integration into society. Although in Brazil they have high mortality rates, resulted to creation of the Statute of Micro and Small Enterprise in order to encourage it through tax benefits and advantages in public procurement processes. However, the other side of the debate, the public procurement process is the moment when the Public Sector relates to the Private Sector to materialize works, services and shopping. These procurement processes have itself weaknesses, such as excessive bureaucracy, delays and corruption, leading us to inquire: is a good idea promotes the development of micro and small enterprises through weaknesses procurement process? This discussion using theoretical framework, and an analysis of two case studies where the winners of procurement were two enterprises benefited from the Statute of Micro and Small Enterprises

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In the current dynamic environment in which the public relations professional is inserted and, considering their ability to perform various activities, the field of events, an area that comprehends many different aspects, ends up being very active and executed by professionals from other fields. The following research demonstrates the importance of the Public Relations professional in the management of an organizational event, aiming to present Public Relations as the area with the most expertize to put plan and organize events, due to the knowledge and theory that can be put into practice. Through a participatory research, the researcher recounts her experience with organizing Carnatlética, event in which she was a part of in 2013. Thus, it is concluded that the participation of a public-relations in the organization is critical to the success of an event, especially in issues related to advertising, media and planning

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Ao refletir sobre a esfera do jornalismo sob influência da lógica mercadológica, esta pesquisa contextualiza teoricamente o cenário atual das características e tendências do jornalismo, especificamente o jornalismo cultural praticado pelo caderno Prosa & Verso, o suplemento literário do jornal carioca O Globo. O presente estudo tem por objetivo estudar a cobertura jornalística do citado suplemento, identifi- cando os valores-notícia presentes nas reportagens de capa, especificamente nos períodos referentes ao ano de 2008 em que ocorrem a Feira Literária Internacional de Paraty e a Bienal Internacional do Livro de São Paulo. Tratando, portanto, da cobertura de eventos do mercado editorial, propõe-se uma análise e reflexão acerca das tensões existentes entre campo jornalístico e campo literário, focando a influência da citada lógica mercadológica na produção jornalística. Com a elaboração da análise dos suplementos veiculados durante a ocorrência de ambos os eventos e a partir das relações entre produção da notícia, imposições de mercado e espetacularização na indústria cultural, verifica-se, entre outras questões, que a notícia não escapa da necessidade de possuir valor de troca, mesmo quando se trata do jornalismo cultural, uma vez que a cultura também tem sua própria economia.

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This study proposes some thinking under a different perspective about the Event Organization Activity. As a directed communication instrument, Events are planned actions, aiming at gathering people with common objectives, for a specific goal, usually under the view of organizations. In this study, some questioning on the relevance of Events at the social movement context is proposed, as they organize themselves through these actions in order to claim and pressure the Government for citizenship rights.

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The lesbian and gay movement has organized itself in Brazil with the goal of creating and making its sexual identity stronger, as well as fighting for its rights and against any homophobic act. This paper analyses the homosexual movement and its relation to building its own identity, as a fighting force. We emphasize the relevance of the manifestation events, such as the LGBT pride parade and, in Bauru, the diversity parade, events that not only provide visibility to the topic, with the presence of the media, but also, represent the voice of these people who search for their citizenship rights.

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This study is based on the mapping of occurrences associated with social vulnerability and natural risks, which refer to the resilience of populations and territories, regarding natural hazards associated with the functioning of natural systems (eg, earthquakes, flood, mass movements). According to UNISDR (2014), the state of São Paulo is a reference in working with Urban Resilience and Disaster in the Resilient Cities Campaign (2014), considering the high investment in Risk Areas Mapping and Public Education Campaigns implemented by the Civil Defense. Thus, this study aims to mapping the occurrence of events related to Tree Falls, Erosion, Landslides, Irregular Housing, Rocky Blocks Falls, Wall Falls, Unroofing and Irregular Construction, attended by the Civil Defense in the city of Santos, São Paulo State, from 2011 to 2014. Thereafter, correlated analyzes to the Environmental Vulnerabilities were generated. The Environmental Vulnerability databases used in this dissertation compose the results of the CNPQ Project - Environmental Vulnerability Mapping of the State of Sao Paulo - Brazil: a methodological contribution of Freitas (2013) and Bortolettoet al (2014), with information collected from the 2010 Census (IBGE, 2010), on a census sectors scale. The adopted methodological procedure involves document analysis followed by data integration in Geographic Information System, through algorithms analysis and mapscrossing.The results obtained in Maps of Social and Environmental Vulnerability Occurrences presented areas of High or Very High Vulnerability. The main variables obtained with such characteristics are Irregular Housing, Landslides and Rocky Blocks Falls, which was associated with hilly terrain formations, with slopes above 30%. To the areas of Medium, Low and Very Low Vulnerability were associated the variables Tree Falls, Wall Falls, Erosion, Unroofing and Irregular Construction, which are spatially distributed without an...

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Pós-graduação em Enfermagem (mestrado profissional) - FMB

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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In a highly competitive and globally integrated market, excellence in production processes has become a survival factor, instead of just a differential point. In this context, companies from various sectors have resorted to philosophies and techniques already established in the literature to improve the efficiency of their production processes. This paper discusses aspects and techniques used to improve the production efficiency of a multinational company that manufactures surgical devices to a global market. Through DMAIC methodology, there were found opportunities to improve machines' efficiency by OEE, an efficiency indicator, in Kaizen Events. A case study was conducted to analyze the methodology and to identify good practices and difficulties along the way

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Os impactos socioeconômicos dos Eventos Extremos de Precipitação Diária em Belém-Pará foram estudados com base em histórias relatadas nas notícias dos jornais da cidade durante o período de 1987 a 2009. Estes eventos foram caracterizados como extremos por meio da Técnica do Decil. O objetivo foi identificar as consequências e os principais bairros afetados pelos eventos extremos de precipitação diária. Os anos que estiveram sob influência do fenômeno El Niño (La Niña) foram os que apresentaram menor (maior) frequência de Eventos Extremos de Precipitação e de noticias publicadas nos jornais da cidade. A variação mensal mostrou que os Eventos Extremos e as notícias dos jornais foram maiores no período "mais chuvoso" (verão/outono austral). As histórias relatadas nas notícias dos jornais da cidade indicaram que o alagamento das ruas é a principal consequência dos eventos extremos para a cidade de Belém-Pará e os bairros mais afetados são Cremação, Jurunas e Batista Campos. Esses bairros são vizinhos e tem como fator comum a presença da bacia hidrográfica da Travessa Quintino Bocaiúva, a qual apresenta baixa declividade e dificulta o escoamento da água, favorecendo a formação de pontos de alagamentos. Identificou-se que a falta de infraestrutura da cidade é o fator predominante quanto à consequência dos eventos extremos de precipitação diária.

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In a highly competitive and globally integrated market, excellence in production processes has become a survival factor, instead of just a differential point. In this context, companies from various sectors have resorted to philosophies and techniques already established in the literature to improve the efficiency of their production processes. This paper discusses aspects and techniques used to improve the production efficiency of a multinational company that manufactures surgical devices to a global market. Through DMAIC methodology, there were found opportunities to improve machines' efficiency by OEE, an efficiency indicator, in Kaizen Events. A case study was conducted to analyze the methodology and to identify good practices and difficulties along the way