Evaluation of morpho-anatomical and chemical differences between varieties of the medicinal plant Casearia sylvestris Swartz

Casearia sylvestris Swartz (Salicaceae) é uma planta utilizada na medicina tradicional, cujos extratos de folhas demonstraram importantes ações farmacológicas. A espécie apresenta variação morfológica, genética e química. Duas variedades são consideradas devido a diferenças morfológicas: C. sylvestris var. sylvestris e var. lingua. Há dificuldades na definição destas variedades. O objetivo deste trabalho é avaliar diferenças morfo-anatômicas e químicas entre as variedades de C. sylvestris que permitam sua diferenciação com aplicação farmacêutica ou botânica. Seções transversais e paradérmicas de folhas foram preparadas para análises morfo-anatômicas, histoquímicas e microscopia quantitativa (indices de estômatos e paliçada). Análises cromatográficas (CLAE-DAD e CCD) foram realizadas para obter o perfil de diterpenos clerodânicos. Os resultados das análises morfo-anatômicas demonstraram diferenças significativas entre as variedades somente em cortes paradérmicos: var. sylvestris - paredes celulares epidérmicas poligonais e hipoestomática, var. lingua - paredes celulares epidérmicas arredondadas e anfiestomática. Os índices de estômatos não revelaram diferenças; os valores dos índices de paliçada foram de 2,8 para var. lingua e 3,9 para var. sylvestris. As análises cromatográficas confirmaram resultados prévios, demonstrando predomínio de diterpenos na var. sylvestris. Este trabalho sugere que análises cromatográficas e morfo-anatômicas podem ser ferramentas aplicáveis na distinção das variedades da espécie.

Influência da vinhaça e da palhada de cana-de-açúcar na sorção de herbicidas aplicados em diferentes solos

Pós-graduação em Agronomia (Agricultura) - FCA

Brasil 2014: análise de peças publicitárias relacionadas à Copa do Mundo

Nesta pesquisa estudamos o espor te com o foco sobre os slogans lançados no processo de preparação da Copa do Mundo a se real izar no Brasi l em 2014. O corpus da pesquisa se const i tui com algumas peças publicitár ias veiculadas na mídia. Anal isamos a mobilização popular e os aspectos que envolvem a adesão em um movimento do país, de modo geral, e a preparação realizada em cada cidade sede, de modo específ ico, com as transformações operadas tanto no âmbito social quanto est rutural. Cartografamos as marcas do empenho do governo para invest i r na transformação dos valores sociais durante a Copa do Mundo, bem como a apropriação do esporte com o objet ivo de fabricar um legado. Ident if icamos como as marcas da integração ent re os povos e do sent imento de pertença dos cidadãos cooperam para os processos de subjet ivação na sociedade contemporânea. Observamos os efeitos de sent ido ocorr idos na divulgação do slogan da campanha publicitária como uma forma de compreender o signif icado da Copa do Mundo em suas relações com a cultura. Part imos da hipótese de que a p ro d u ç ã o d a “p a i x ã o pelo futebol ” t em s e u s e n t id o amp lia d o p a ra a sugestão massiva de est i los de vida. Assim, estabele cemos uma f ro n t e ira e n t re o s “e f e it o s d e s e n t id o s ” e o s “e f e it o s d e ima ge n s ” n o s múlt iplos usos do slogan. Na const ituição do corpus de nossa pesquisa ident if icamos as marcas dos vínculos estabelecidos pela publ icidade com a Copa do Mundo. Nosso estudo se situa no campo dos estudos sobre as relações entre o esporte e os processos de subjet ivação na sociedade atual. Interessa-nos observar as implicações entre o corpo e os processos de subjet ivação nas peças publicitárias selecionadas para este estudo.

Desempenho em tarefas computacionais em função do uso de diferentes periféricos

With the popularization of information technology and government incentives for inclusion in the digital era, an important issue for science and for industry is the design of tool s for entrance of input to the device, that is , the peripherals at tached to the computer that are reaching the consumer. In order to minimize the impact of repetitive use of these tools for entry, whether when playing games or working, more studies are in need to developper ipherals that enable comfort and effi ciency. This study examined the per formance of individuals with differents izes of hand (i.e., large and small ) in performance of three task s on the computer us ing mouses of small and large sizes. For thi s study, 19 young adul ts were volunteers and asked to per form activities with greater precision and speed. In addition, al l participants were asked on the use of computers. The results showed no statistically significant differences in the performance related to the size of the mouse between subjects with small and large hands. However, an interest ingresult as observed with respect to the performance of individuals with a large hand to perform tas ks more quickly. The results of this study suggest that with both, the small and the large mouse, individuals with big hands have a fas terper formancein tasks of dragging and clicking when compared with the performance of indi viduals with small hand.

Estudo fitoquímico da espécie Aristolochia giberti (Aristolochiaceae)

O interesse pelo estudo fitoquímico e biológico das espécies pertencentes à Aristolochiaceae é devido ao vasto uso desta na medicina tradicional e homeopática. Muitas das espécies pertencentes ao gênero Aristolochia têm apresentado atividades diversas como antiinflamatórias, sedativas, diuréticas e abortivas. O presente trabalho descreve o isolamento, a identificação e a elucidação estrutural dos constituintes químicos da Aristolochia giberti, utilizando métodos de partição e cromatográficos. O extrato acetônico de folhas da espécie foi fracionado por cromatografia em coluna de sílica gel, sendo as frações resultantes analisadas por cromatografia em camada delgada comparativa e posteriormente por métodos espectrométricos (IV, UV, EM, RMN de 1 H e de 13 C) e análise elementar (C, H, N e S), identificando assim um total de cinco substâncias: ácido copálico, ácido ent-labdan-8-ol-15-óico, a lignana kusunoquinina, e os dois epímeros da cubebina. Da mesma forma, o extrato acetônico de raízes foi submetido ao mesmo tipo de fracionamento e às mesmas análises utilizadas no acetônico de folhas, resultando na identificação de quatro substâncias: ácido 13,14-dihidrocolavênico (composto até então não obtido da espécie A. giberti), os dois epímeros da cubebina e a kusunoquinina

Explorando abordagens de aprendizado sequencial para floresta de caminhos ótimos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Analisando a possibilidade de um anel ao redor de um satélite

On November 26 th, 2005, Rhea, one of Saturn's moons, is found by Cassini spacecraft approximately at 5.105 km from Saturn. Observations in situ reveal that electrons are depleted in the moon's vicinity. However, Rhea is considered massive enough to retain a thin atmosphere. Assumption was that the atmosphere of Rhea was not composed exclusively of gas, its likely contains solid material that can absorb magnetospheric particles. According to Jones et al. (2008), these particles were in a speci c position so that at the moment of observation the electrons could not be detected. In opposition to this idea there is a group, Tiscareno et al. 2010, Cornell University Library, that underwent intensive search for any material that might be orbiting Rhea using Cassini images, however the could not identify any. Second recommendation made by American researchers and other countries, and accepted by the National Board of Research the Cassini Equinox Mission will continue in orbit around Saturn until 2016.The probe will perform several maneuvers with high inclination to delve into the main ring system, and then enter in Saturn's atmosphere and collide with planet. This research is of great importance because until today no rings were found orbiting satellites. The goal of this work is to analyze the orbital evolution of a set of particles around Rhea disturbance of Saturn, J2 e J4 and check results by the numerical simulations and the possibility of a stable ring orbiting Rhea.

Chemical and morphological features of nanofilled composite resin: influence of finishing and polishing procedures and fluoride solutions

This study evaluated the influence of finishing and polishing procedures and differ-ent fluoride solutions on superficial morphology and chemistry of the nanofilled composite resinSupreme XT (3M) through the EDX analysis and SEM evaluation. Circular specimens (n 5 30) of 10mm diameter and 2 mm thickness were prepared, with half of the sample assays finished and polishedwith Super-Snap1sandpaper. The experimental groups were divided according to the presence or ab-sence of finishing and polishing and solutions (arti ficial saliva, 0.0 5% of manipulated sodium fluoridesolution, Fluordent Re ach, Oral B, Fluorgard). Specimens were immersed in each respective solutionfor 1 min per day, during 60 days and stored in artificial saliva at 37 6 18C between immersion peri-ods. Topography and chemical analysis was qualitative. It was observed that specimens submitted tofinishing and polishing procedures had lower superficial degradation. Fluoride solutio ns promoted su-perficial alterations on specimens, being the highest degradation obtained with Fluordent Reach. Itca n be concluded that finishing and polishing procedures and the immersion media influence the su-perficial morphology of composite resin tested; the Fluordent Reach was the flu oride solution thatmo st affected the material’s surface.

Immunomodulatory action of Copaifera spp oleoresins on cytokine production by human monocytes

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Chitin-degrading enzymes from an actinomycete ectosymbiont of Acromyrmex subterraneus brunneus (Hymenoptera: Formicidae)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Structure and absolute configuration of diterpenoids from hymenaea stigonocarpa

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Lignans and diterpenes of three Aristolochia species

Phytochemical examination of Aristolochia cymbifera, A. esperanzae and A. galeata led to the isolation of furofuran and dibenzylbutyrolactone type lignans, as well as of clerodane and ent-labdane type diterpenes. Structural assignments for two new ent-labdans are presented and discussed. © 1988.

Evaluation of nasal obstruction in various sagittal skeletal deformity of jaws

Nasal obstruction (NO) is a common symptom present in 25% of the general population, which significantly interferes with the quality of life. The different facial profiles and malocclusion patterns could be associated with the degree of NO. In order to evaluate the nasal function in patients with different facial morphology patterns, the authors developed a prospective study in which 88 patients from a dentofacial deformities center were included. These patients were submitted to fibrorhinoscopy (Mashida, ENT PIII) with a 3.2-mm cannula under topical anesthesia to evaluate septal deviation, inferior and medium turbinates, and pharyngeal tonsils. The 88 patients included in the study were divided into 3 groups according to the classification of the facial profile, distributed as follows: 32 class I, 28 class II, and 28 class III; the data collected was statistically analyzed by analysis of variance and the results are shown. The patients included in this study presented similar prevalence of NO with the reduction of airway function efficiency. Although it was not a statistically different, the group II presented higher mean Nasal Obstruction Syndrome Evaluation scores.

As contribuições da Pedagogia Waldorf no atendimento a diversidade e na valorização das diferenças

The ideal of Waldorf Education, since the opening of the first school in 1919, was based on innovative principles for a humanized society. Among those principles, there was the attendance of all children without distinction, which is exactly the main idea of the inclusive school. Waldorf pedagogy defends that under the right pedagogical action and care with the individual development, anyone can develop, regardless of their disability. This statem ent highlights the main objective of this methodology, that is the human development, aligned to another fundamental guideline of inclusive education. Accordingly, the hypothesis of this work is that Waldorf education promotes inclusive schooling contexts, attending diversity and valuing differences. The general objective of this study is: analyze Waldorf Education to verify if it promotes inclusive contexts. And the specific objetives were: identify elements in this practice that favors diversity attend; analyze the practice of a Waldorf school, considering documentation, structure, and conception of managers, teachers and parents. The study was based on quantitative and qualitative research approach, and the data was collected trough observation of teaching practices in a classroom where a disabled student was present, as well as through documentation and observation of the school environment. Furthermore, in order to verify the understanding of parents (71 individuals) and teachers (18 individuals) on inclusion, a specific questionnaire was developed for each of these two groups. For the records, a diary and an observation script were used. It was concluded that Waldorf methodology provides all the necessary conditions to inclusion, mainly due to it's enhancement of individuality, didactic organization and it's roots in social relations

Estudo da diversidade genética e química e produção do epímero do ácido caurenóico em calos de croton antisyphiliticus mart

Pós-graduação em Agronomia (Horticultura) - FCA