The "freedom to frame questions... worth asking" or three stories and three (other) fragments of research

In our state of centralised control of the curriculum and high-stakes testing an examination subject's assessment objectives have become high profile. Some of the anomalous effects of this profile are shown in the teaching, question-setting, and marking of English literature. Glimpses of earlier times are revealed, all three secondary school key stages are considered, examination performances are discussed, and the views of beginning teachers about teaching to the test are sought.

Towards cost-sensitive adaptation: when is it worth updating your predictive model?

Our digital universe is rapidly expanding,more and more daily activities are digitally recorded, data arrives in streams, it needs to be analyzed in real time and may evolve over time. In the last decade many adaptive learning algorithms and prediction systems, which can automatically update themselves with the new incoming data, have been developed. The majority of those algorithms focus on improving the predictive performance and assume that model update is always desired as soon as possible and as frequently as possible. In this study we consider potential model update as an investment decision, which, as in the financial markets, should be taken only if a certain return on investment is expected. We introduce and motivate a new research problem for data streams ? cost-sensitive adaptation. We propose a reference framework for analyzing adaptation strategies in terms of costs and benefits. Our framework allows to characterize and decompose the costs of model updates, and to asses and interpret the gains in performance due to model adaptation for a given learning algorithm on a given prediction task. Our proof-of-concept experiment demonstrates how the framework can aid in analyzing and managing adaptation decisions in the chemical industry.

Whatever it takes: rivalry and unethical behavior

This research investigates the link between rivalry and unethical behavior. We propose that people will engage in greater unethical behavior when competing against their rivals than when competing against non-rival competitors. Across a series of experiments and an archival study, we find that rivalry is associated with increased use of deception, unsportsmanlike behavior, willingness to employ unethical negotiation tactics, and misreporting of performance. We also explore the psychological underpinnings of rivalry, which help to illuminate how it differs from general competition, and why it increases unethical behavior. Rivalry as compared to non-rival competition was associated with increased status concerns, contingency of self-worth, and performance goals; mediation analyses revealed that performance goals played the biggest role in explaining why rivalry promoted greater unethicality. Lastly, we find that merely thinking about a rival can be enough to promote greater unethical behavior, even in domains unrelated to the rivalry. These findings highlight the importance of rivalry as a widespread, powerful, yet largely unstudied phenomenon with significant organizational implications. Further, the results help to inform when and why unethical behavior occurs within organizations, and demonstrate that the effects of competition are dependent upon relationships and prior interactions.

Inhibitory Signals Mediated by Programmed Death-1 Are Involved With T-Cell Function in Chronic Periodontitis

Background: Inhibitory signals mediated via molecules such as programmed death-1 (PD-1) play a critical role in downmodulating immune responses and maintaining peripheral tolerance. We investigated the involvement of cytokines and PD-1 engagement in mediating the T-cell unresponsiveness to bacterial and ubiquitous antigens in periodontal diseases. Methods: Gingival and peripheral blood samples from healthy individuals and patients with chronic periodontitis were collected and used for the subsequent assays. Leukocytes in the lesion site and blood were evaluated using flow cytometry. The production of interferon-gamma, interleukin-10, and transforming growth factor-P proteins was evaluated by enzyme-linked immunosorbent assay (ELISA), and the presence of PD-1+cells in the inflamed gingiva was confirmed by immunofluorescence confocal microscopy for CD4 and PD-1 colocalization. Results: T cells from patients with chronic periodontitis proliferated poorly in response to Aggregatibacter actinomycetem comitans (previously Actinobacillus actinomycetemcomitans) antigen. T-cell unresponsiveness was not associated with imbalanced cytokine production. However, T cells from patients with chronic periodontitis expressed significantly higher levels of PD-1 either upon isolation or after culture with antigens. Moreover, PD-1 blocking did not result in significant T-cell proliferation in cells cultured with phytohemagglutinin or bacterial antigens. The blockade of PD-1 resulted in the increased production of IFN-gamma. In addition, CD4+ and CD8+ T cells expressing PD-1 accumulated in lesions with chronic periodontitis. Conclusion: These data show that PD-1 engagement could be involved in the modulation of IFN-gamma production by T cells in patients with chronic periodontitis. J Periodontol 2009,80:1833-1844.

Ett svenskt skattesystem under förändring : Århundradets skattereform 1902

Större delen av 1800-talet framstår som en misslyckad beslutsprocess när det gäller skatte-politiken i Sverige. Eftersträvade förändringar av skattesystemet var en trögrörlig process med mycket motstånd mot att göra förändringar i vårt gamla feodala skattesystem som hade anor från medeltiden. När 1800-talet börjar närma sig sitt slut stod plötsligt skattefrågorna högt upp på den politiska dagordningen. Arbetarna ville ha rösträtt och krävde att tullarna skulle avskaffas. Bönderna ville befrias från grundskatterna och de konservativa ville avskaffa in-delningsverket och ersätta den med en modern värnpliktsarmé. Den gemensamma nämnaren blir skattereformen 1902.Syftet i min uppsats har varit att undersöka denna skattereform som egentligen skulle vara en provisorisk skattereform som skulle tillämpas under ett år, 1903. Skattereformen bestod av tre delar som jag har undersökt varav det första är införandet av en progressiv beskattning. Det andra är införandet av självdeklarationen och det sista en reformering av taxeringsförfarandet.Resultatet av skattereformen vart så lyckad och gav väsentligt högre skatteintäkter till staten. Grunddragen i skattereformen kom att permanentas och följas av nya skattereformer. Nu nästan 110 år senare, är Sveriges skattesystem uppbyggt på samma sätt som det fastställdes i skattereformen 1902.