1000 resultados para Walker, William, 1824-1860.


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Ink on linen; location, type, amounts of plantings; footpaths, pool; some plantings areas crossed-out with pencil; signed; 79 x 38 cm. [from photographic copy by Lance Burgharrdt]

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Added title-pages, engraved (with vignette) : The plays of William Shakspeare, illustrated with engravings by George B. Ellis, from the designs of R. Smirk, R. A.

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I. 1554-86.--II. 1586-89.--III. 1590-1600.--IV. 1600-09.

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Mode of access: Internet.

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The plates and portraits are printed on both sides.

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BACKGROUND: Patients with advanced cancer suffer from cachexia, which is characterised by a marked weight loss, and is invariably associated with the presence of tumoral and humoral factors which are mainly responsible for the depletion of fat stores and muscular tissue. METHODS: In this work, we used cytotoxicity and enzymatic assays and morphological analysis to examine the effects of a proteolysis-inducing factor (PIF)-like molecule purified from ascitic fluid of Walker tumour-bearing rats (WF), which has been suggested to be responsible for muscle atrophy, on cultured C2C12 muscle cells. RESULTS: WF decreased the viability of C2C12 myotubes, especially at concentrations of 20-25 mug.mL-1. There was an increase in the content of the pro-oxidant malondialdehyde, and a decrease in antioxidant enzyme activity. Myotubes protein synthesis decreased and protein degradation increased together with an enhanced in the chymotrypsin-like enzyme activity, a measure of functional proteasome activity, after treatment with WF. Morphological alterations such as cell retraction and the presence of numerous cells in suspension were observed, particularly at high WF concentrations. CONCLUSION: These results indicate that WF has similar effects to those of proteolysis-inducing factor, but is less potent than the latter. Further studies are required to determine the precise role of WF in this experimental model. © 2008 Yano et al; licensee BioMed Central Ltd.

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Annually, the association publishes a journal, The Proceedings, which consists of papers presented at the annual meeting. William Gilmore Simms— Almost a Historian by Hampton M. Jarrell United States Aggrandizement, 1850-1860— the Walker Expeditions as an Illustrative Case by William H. Patterson Xenophobia in the South by G. A. Buchanan, Jr.

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La presente investigación propone un análisis sobre la crisis política de Crimea en 2014 a partir del influjo que las migraciones desde Rusia han tenido en la historia reciente. Así, a partir de la evaluación de algunos de los momentos de inmigración más representativos en los últimos dos siglos (1860, 1928 y 1991) se vincula el proceso de construcción de la identidad de los inmigrantes -transversal en diferentes periodos históricos en Crimea- con el desarrollo de los eventos de 2014. Lo anterior permite identificar un cierto legado de la migración hacia Crimea en el desarrollo de la crisis, cuyo resultado principal ha sido la anexión de facto de Crimea a Rusia. Ésta no habría sido posible sin el particular ánimo de afinidad con la idea de Rusia –o Russianness- de la mayoría de los habitantes de la península, cuya presencia en la región se explica en parte, a través de los procesos migratorios antes descritos.