Stamping room; Paul I. Landmann manufacturing factory; Mannheim-Neckarau Business Establishments; Factories

"Pragesaal"

Studio and office; Paul I. Landmann manufacturing factory; Mannheim-Neckarau Business Establishments; Factories

"Atelier und Buero"

Paul I. Landmann manufacturing factory; Mannheim-Neckarau Business Establishments; Factories

"Fabrikansicht von der Toreinfahrt"

Factory employee housing; Paul I. Landmann Manufacturing Factory; Mannheim-Neckarau Business Establishments; Factories

"Arbeiter und Mietshaeuser"

Factory employee housing; Paul I. Landmann Manufacturing Factory; Mannheim-Neckarau Business Establishments; Factories

"Arbeiter und Mietshaeuser"

Lucien Levy-Bruehl, Albert Einstein, Franz Oppenheimer, Arthur Liebert and his son, Paul Tillich, unidentified woman and Mrs. Charles Blondel outside the Grand Hotel Curhaus during the Davoser Hochschulkurse; Davos, Switzerland Portraits Groups

The Davoser Hochschulkurse took place for the first time in 1928. Mainly university teachers from Germany, France, Switzerland (perhaps elsewhere) offered lectures to students recovering from tuberculosis at the health resort in the Swiss mountains. The lecturers were accommodated at the Grand Hotel Curhaus, where the lectures also took place.

50th wedding anniversary party of Paul Goldschmidt and Ilse nee Molling; Laguna Hills, CA.

Left to right: Margot Molling, Ilse Molling, Adolf Molling, Paul Goldschmidt (husband of Ilse Molling)

50th wedding anniversary party of Paul Goldschmidt and Ilse nee Molling; Laguna Hills, California.

left to right: Margot Molling, Ilse Molling, Adolf Molling, Paul Goldschmidt (husband of Ilse Molling)

New genetic loci link adipose and insulin biology to body fat distribution

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10−8). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms.

Studio portrait of the wood merchant Hermann Judey with his stepson Paul Portraits Family

Paul was the son from a previous marriage of Hermann's first wife Olga Judey nee Fischmann

Studio portrait of Paul and Rahel Portraits Couples

Paul was the son from a previous marriage of Hermann Judey's first wife Olga Judey nee Fischmann

Paul and Rahel in a car with an unidentified chauffeur; Berlin Portraits Couples

Paul was the son from a previous marriage of Hermann Judey's first wife Olga Judey nee Fischmann

Portrait of Paul Kraft; Stockholm Portraits Men

Digital Image

Reproduction of studio portrait of Julie Ehrenberg nee Fischel Portraits Women

Original held by Paul Ehrenberg