Elektrophysiologie.

Disbound Original Held in Oak Street Library Facility.

Puissance de l'électricité animale, ou, Du magnétisme vital et de ses rapports avec la physique, la physiologie et la médecine ... / par J. Pigeaire ...

BMC: v. 189, col. 900.

Recherches sur les causes particulieres des phénoménes électriques, et sur les effets nuisibles ou avantageux qu'on peut en attendre.

Mode of access: Internet.

Essai sur l'électricité des corps.

Mode of access: Internet.

The measurement of induction shocks; a manual for the quantitative use of Faradic stimuli,

Mode of access: Internet.

Memoirs on the physiology of nerve, of muscle, and of the electrical organ.

No more published?

Studies in electro-physiology (animal and vegetable)

Plates printed on both sides.

On certain electrical processes in the human body and their relation to emotional reactions /

"Literature on the 'psychogalvanic reflex' and allied phenomena": p. 39.

A practical treatise on the medical and surgical uses of electricity. Including: localized and general faradization; localized and central galvanization; electrolysis and galvano-cautery.

Mode of access: Internet.

Bioelectric fields and growth, with a Bibliography of continuous bioelectric currents and bioelectric fields in animals and plants, by H. F. Rosene.

Bibliography : p. [290]-391.

Comparative electro-physiology,

Mode of access: Internet.

Elements of electro-biology.

Mode of access: Internet.

A comprehensive analysis of sexual dimorphism in the midbrain dopamine system

Thesis (Ph.D.)--University of Washington, 2016-06

Molecular determinants of ginkgolide binding in the glycine receptor pore

Ginkgolides are potent blockers of the glycine receptor Cl- channel (GlyR) pore. We sought to identify their binding sites by comparing the effects of ginkgolides A, B and C and bilobalide on alpha 1, alpha 2, alpha 1 beta and alpha 2 beta GlyRs. Bilobalide sensitivity was drastically reduced by incorporation of the beta subunit. In contrast, the sensitivities to ginkgolides B and C were enhanced by beta subunit expression. However, ginkgolide A sensitivity was increased in the alpha 2 beta GlyR relative to the alpha 2 GlyR but not in the alpha 1 beta GlyR relative to the alpha 1 GlyR. We hypothesised that the subunit-specific differences were mediated by residue differences at the second transmembrane domain 2' and 6' pore-lining positions. The increased ginkgolide A sensitivity of the alpha 2 beta GlyR was transferred to the alpha 1 beta GlyR by the G2'A (alpha 1 to alpha 2 subunit) substitution. In addition, the alpha 1 subunit T6'F mutation abolished inhibition by all ginkgolides. As the ginkgolides share closely related structures, their molecular interactions with pore-lining residues were amenable to mutant cycle analysis. This identified an interaction between the variable R2 position of the ginkgolides and the 2' residues of both alpha 1 and beta subunits. These findings provide strong evidence for ginkgolides binding at the 2' pore-lining position.

mu O-conotoxin MrVIB selectively blocks Na(v)1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits

The tetroclotoxin-resistant voltage-gated sodium channel (VGSC) Na(v)1.8 is expressed predominantly by damage-sensing primary afferent nerves and is important for the development and maintenance of persistent pain states. Here we demonstrate that mu O-conotoxin MrVIB from Conus marmoreus displays substantial selectivity for Na(v)1.8 and inhibits pain behavior in models of persistent pain. In rat sensory neurons, submicromolar concentrations of MrVIB blocked tetroclotoxin-resistant current characteristic of Na(v)1.8 but not Na(v)1.9 or tetroclotoxin-sensitive VGSC currents. MrVIB blocked human Nav1.8 expressed in Xenopus oocytes with selectivity at least 10-fold greater than other VGSCs. In neuropathic and chronic inflammatory pain models, allodynia and hyperalgesia were both reduced by intrathecal infusion of MrVIB (0.03-3 nmol), whereas motor side effects occurred only at 30-fold higher doses. In contrast, the nonselective VGSC blocker lignocaine displayed no selectivity for allodynia and hyperalgesia versus motor side effects. The actions of MrVIB reveal that VGSC antagonists displaying selectivity toward Na(v)1.8 can alleviate chronic pain behavior with a greater therapeutic index than nonselective antagonists.