[¿Cuál es la educacion fisica y moral de la mujer, mas conforme á los grandes destinos la ha confiado la providencia?] : discurso leido en la Universidad Central por el Licenciado D. Luis de Hysern y Catá en el solemne acto de recibir la investidura de Doctor en la Facultad de Medicina.

Tesis doctoral Univ. Central, 1864.

El tesoro de los niños : obra util para su cristiana y civil educacion /

Tít. orig.: Le Trésor des enfants, Paris, 1810.

Apendice a la educacion popular.

Mode of access: Internet.

Biblioteca Britanica ó Coleccion extractada de las obras inglesas, de los periodicos, de las memorias y transacciones de la sociedades y academias de la Gran Bretaña, de Asia, de Africa y de America : comprehendiendo principalmente la historia, la geografia, los viages, las obras de educacion, las novelas y ficciones agradables.

Contiene: T. I - T.II (277, [3] p.)

Ortografía práctica ó sea Uso de las letras y acentuacion : ilustrada con varias notas para los establecimientos de educacion /

Mode of access: Internet.

[¿Cuál es la educacion de la mujer, mas conforme á los destinos que la providencia la ha confiado] : Discurso pronunciado ante el claustro de la Universidad Central por el Licenciado D. Gabino Rufilanchas Lapeira, en el acto solemne de recibir la investidura de doctor en la Facultad de Medicina y Cirugía.

Tesis Universidad Central, 1859.

[¿Cuál es la educacion fisica y moral de la mujer, mas conforme á los grandes destinos la ha confiado la providencia?] : Discurso leido en la Universidad Central por el Licenciado don Juan Perez y Garcia, del Cuerpo de Sanidad de la Armada, en el ejercicio del grado de doctor en Medicina, y en el acto de recibir la investidura del mismo el dia 24 de octubre de 1859.

Tesis Universidad Central, 1859.

Modern motherhood; a book of information on complete maternity care: prenatal - delivery - aftercare,

Bibliography: p. [243]-252; "Suggested reading" at end of chapter on development of the child.

Educacion civico-militar : conferencia pronunciada en el Centro del Ejercito y de la Armada, la noche del 21 de febrero de 1903 /

At head of title: Publicaciones de los "Estudios Militares".

Disertacion sobre la educacion de la voluntad : leida en el Congreso pedagogico/

Mode of access: Internet.

Prenatal diagnosis of tetrasomy 18p using multiplex fluorescent PCR and comparison with a variety of techniques

We report genetic characterization of isochromosome 18p using a combination of cytogenetic and molecular genetic methods, including multiplex fluorescent PCR. The patient was referred for chorionic villus sampling (CVS) due to advanced maternal age and maternal anxiety. The placental karyotype was 47,XX,+mar, with the marker having the appearance of a small supernumerary isochromosome. Because differentiating between isochromosomes and other structural rearrangements is normally very difficult, a variety of genetic tests including fluorescence in situ hybridization (FISH), PCR, and multiplex fluorescent PCR were undertaken to determine chromosomal origin and copy number and, thus, allow accurate diagnosis of the corresponding syndrome. FISH determined that the marker chromosome contained chromosome 18 material. PCR of a variety of short tandem repeats (STRs) confirmed that there was at least one extra copy of the maternal 18p material. However, neither FISH nor PCR could accurately determine copy number. Multiplex fluorescent PCR (MF-PCR) of STRs simultaneously determined that: (1) the marker included 18p material; (2) the marker was maternal in origin; (3) allele copy number indicated tetrasomy; and (4) contamination of the sample could be ruled out. Results were also rapid with accurate diagnosis of the syndrome tetrasomy 18p possible within 5 hours.

Combined prenatal and chronic postnatal vitamin D deficiency in rats impairs prepulse inhibition of acoustic startle

There is growing evidence that 1,25-dihydroxyvitamin D-3 is involved in normal brain development. The aim of this study was to examine the impact of prenatal and postnatal hypovitaminosis D on prepulse inhibition (PPI) of acoustic startle in adult rats. We compared six groups of rats: control rats with normal vitamin D throughout life and normal litter size (Litter); control rats with normal vitamin D but with a reduced litter size of two (Control); offspring from reduced litters of vitamin D deplete mothers who were repleted at birth (Birth), repleted at weaning (Weaning) or remained on a deplete diet until 10 weeks of age (Life); or control rats that were placed on a vitamin D-deficient diet from 5 to 10 weeks of age (Adult). All rats were tested in acoustic startle chambers at 5 and 10 weeks of age for acoustic startle responses and for PPI. There were no significant group differences at 5 weeks of age on the acoustic startle response or on PPI. At 10 weeks of age, rats in the Life group only had impaired PPI despite having normal acoustic startle responses. We conclude that combined prenatal and chronic postnatal hypovitaminosis D, but not early life hypovitaminosis D, alters PPI. (C) 2004 Elsevier Inc. All rights reserved.

Transient prenatal vitamin D deficiency is associated with hyperlocomotion in adult rats

Rat experiments have shown that prenatal Vitamin D deficiency leads to altered neonatal brain morphology, cell density and neurotrophin expression. In the current study we examined the hypothesis that Vitamin D deficiency during early development alters adult behaviour even when there is an intervening period in which the animal receives normal Vitamin D in later development. Rats were conceived and born to Vitamin D deficient dams (Birth); conceived, born and weaned from Vitamin D deficient dams (Weaning); or deficient in Vitamin D from conception to 10 weeks of age (Life). Litters were standardized to three males and three females per litter. All rat offspring were rendered normocalcaemic with calcium supplemented water (2 mM) after weaning. Control animals were born to mothers fed a normal diet but subject to similar litter size and calcium supplementation. At 10 weeks all animals were tested on the holeboard test, elevated plus maze test, social interaction observation, acoustic startle response test, prepulse inhibition of the acoustic startle response and a forced swim test. Early Vitamin D deficiency (Birth group) enhanced locomotion in the holeboard test and increased activity in the elevated plus maze. Thus, transient prenatal Vitamin D deficiency induces hyperlocomotion in adulthood, without severe motor abnormalities. (C) 2004 Elsevier B.V. All rights reserved.