Molecular approaches for eco-epidemiological studies of Paracoccidioides brasiliensis

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

An eco-friendly protocol for synthesis of thiourea derivatives: 1-benzoyl-3-benzylguanidine and 1-benzoyl-3-benzyl-O-ethylisourea. A possible non-purely thermal microwave assisted reaction

1-Benzoyl-3-benzylguanidine and 1-benzoyl-3-benzyl-O-ethylisourea were synthesized in good yields (68 and 76%, respectively) from 1-benzoyl-3-benzylthiourea and benzoyl-ethylthiocarbamate in dry media conditions using KF-Al2O3 under microwave irradiation. Strong nucleophilic amines promoted the sulfur elimination by attack on the thiocarbonyl group in both thiourea and thiocarbamates to afford guanidines and isourea, respectively. Transesterification products were obtained from p-TsOH catalyzed reaction of thiocarbamate with alcohols under MW-solvent-free conditions. Very important non-purely thermal MW specific effects were evidenced and attributed to stabilization by coulombic interactions between materials and waves. (c) 2005 Elsevier Ltd. All rights reserved.

Identificacao e mapeamento de areas de maior eficiencia fotossintetica para a cana-de-acucar

The objective was the study of better areas for sugar cane exploitation, using variables related to the classes and exposition of slopes, edaphic and climatic variables. Data were analysed with the aid of a Geographic Information System supported by 8 bit microcomputer, and maps of North exposition, photosynthetically the most efficient, were produced for different gradients of slope. These maps combined with traditional maps can be a very helpful tool to planners. -from English summary

Eficiencia y equidad en el sistema de salud chileno

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Educación, eficiencia y equidad

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Educación, eficiencia y equidad: una difícil convivencia

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En búsqueda de efectividad, eficiencia y equidad: las políticas del mercado de trabajo y los instrumentos de su evaluación

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Pequeñas y medianas empresas y eficiencia colectiva: estudios de caso en América Latina

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Gestión social: cómo lograr eficiencia e impacto en las políticas sociales

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La búsqueda de la eficiencia dinámica: dinámica estructural y crecimiento económico en los países en desarrollo

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Importance of xenarthrans in the eco-epidemiology of Paracoccidioides brasiliensis

Background. Several pathogens that cause important zoonotic diseases have been frequently associated with armadillos and other xenarthrans. This mammal group typically has evolved on the South American continent and many of its extant species are seriously threatened with extinction. Natural infection of armadillos with Paracoccidioides brasiliensis in hyperendemic areas has provided a valuable opportunity for understanding the role of this mammal in the eco-epidemiology of Paracoccidioidomycosis (PCM), one of the most important systemic mycoses in Latin America. Findings. This study aimed to detect P. brasiliensis in different xenarthran species (Dasypus novemcinctus, Cabassous spp., Euphractus sexcinctus, Tamandua tetradactyla and Myrmecophaga tridactyla), by molecular and mycological approaches, in samples obtained by one of the following strategies: i) from road-killed animals (n = 6); ii) from naturally dead animals (n = 8); iii) from animals that died in captivity (n = 9); and iv) from living animals captured from the wild (n = 2). Specific P. brasiliensis DNA was detected in several organs among 7/20 nine-banded armadillos (D. novemcinctus) and in 2/2 anteaters (M. tridactyla). The fungus was also cultured in tissue samples from one of two armadillos captured from the wild. Conclusion. Members of the Xenarthra Order, especially armadillos, have some characteristics, including a weak cellular immune response and low body temperature, which make them suitable models for studying host-pathogen interaction. P. brasiliensis infection in wild animals, from PCM endemic areas, may be more common than initially postulated and reinforces the use of these animals as sentinels for the pathogen in the environment. © 2009 Bagagli et al; licensee BioMed Central Ltd.

Situación y perspectivas de la eficiencia energética en América Latina y el Caribe = Situation and perspectives on energy efficiency in Latin America and the Caribbean

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Indicadores de políticas públicas en materia de eficiencia energética en América latina y el Caribe

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Development of eco-efficient and sustainable urban infrastructure in Asia and Latin America: eco-efficiency and sustainable infrastructure in the United States and Canada

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Eficiencia energética en América Latina y el Caribe: avances y desafíos del último quinquenio

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