920 resultados para Curry-Howard
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A avaliação do desempenho e a sua aplicação são, no actual enquadramento socioeconómico, cada vez mais necessárias, como forma de melhorar a eficácia e a eficiência entre as organizações. Para a prática profissional verifica-se que a implementação da avaliação de desempenho, apresenta lacunas que podem comprometê-la. Sabendo da importância do profissional para o sucesso da implementação da avaliação de desempenho, toma-se fundamental, analisar a sua percepção face ao modelo e sua implementação. O problema da instrução do presente estudo pretende saber quais as percepções dos técnicos de radiologia avaliados sujeitos ao modelo de avaliação de desempenho implantado no Hospital Curry Cabral. Tendo como objectivo ao nível da gestão, minimizar os obstáculos de implementação e maximizar os pontos fortes. Após pesquisa bibliográfica sobre os principais conceitos, foi definido domo objectivo da investigação empírica: - Comparar as percepções dos técnicos de radiologia submetidos ao modelo de avaliação desempenho ”Pró-Activo”. Recorrendo a uma metodologia exploratória e descritiva, estudámos o impacto dessas ferramentas utilizadas dentro da Unidade Hospitalar do estudo. A metodologia de recolha de informação aos profissionais expostos do estudo assentou em questionários de perguntas fechadas e abertas ambas com uma abordagem de carácter quantitativo. Para a análise e tratamento dos dados utilizou-se programas informáticos. As principais conclusões: verifica-se a falta de formação para todos os envolvidos, um processo desprovido de imparcialidade, neutralidade e rigor, bem como uma motivação geral dos profissionais em matéria de avaliação de desempenho. ABSTRACT - The evaluation of performance and its implementation are, in the current socioeconomic framing, each time more necessary as form to improve the effectiveness and the efficiency amidst the organizations. For the practical professional it is verified that the implementation of the performance evaluation, presents gaps that can compromise it. Knowing the importance of the individuals in the success of the implementation of the performance evaluation, it becomes basic to analyze its perceptions face to the model and its implementation. The problem of inquiry of this study pretends to know which the perceptions of the technicians of radiology evaluated and appraisers face to the models of evaluation of performance implanted in the Portuguese Hospitals (Hospital Curry Cabral). The purpose to the level of the management is to minimize the obstacles of implementation and to maximize the strong points. Bibliographical research on the main concepts was effectuated, after what we define the objectives of empirica inquiry: - To compare the perceptions of the radiology technicians subjected to models of performance evaluation “Pro-Activa”. Using an exploratory and descriptive approach, studied the impact of these tools used in the hospitals of the study. The methodology for collecting information to professionals out of the study based on questionnaires of both open and closed questions with a quantitative approach to nature. For analysis and data processing software was used. The main conclusions: there is the lack of training for all involved, a process devoid of impartiality, neutrality and accuracy, as well as a general motivation of the professionals regarding the evaluation of performance.
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Partial cadastral map showing lots in path of proposed avenue extension.
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Os sistemas de informação, enquanto ferramenta da gestão, podem contribuir para o desenvolvimento das organizações sendo atualmente visível esta preocupação nos órgãos de gestão dos serviços de saúde. No processo de implementação dos sistemas de informação a economia da informação assume um destaque pela sua componente de mais-valia. No presente trabalho, fizemos uma caracterização dos sistemas de informação utilizados no serviço de radiologia do hospital Curry Cabral e percebemos como os profissionais trabalhavam e atualizavam a informação nesses mesmos sistemas. Analisámos posteriormente a produtividade através de índices criados para o próprio serviço, antes e depois da implementação dos sistemas de informação, para entender até que ponto podemos falar da economia da informação. Através de uma abordagem quantitativa pretendeu-se a realização de um estudo descritivo com recurso à técnica de inquérito através de questionário aplicado a 55 profissionais do serviço, nomeadamente a 17 médicos de radiologia, a 6 administrativas e a 31 técnicos de radiologia. De uma forma geral, os dados obtidos nesta investigação permitem verificar que a atualização dos sistemas de informação por parte dos profissionais deste serviço ocorre de uma forma bem conduzida e cuidada, nomeadamente pelos técnicos de radiologia. Entendemos também que de uma forma geral todos os profissionais estão cientes que os sistemas de informação contribuem para o auxílio na gestão principalmente devido a uma melhor monitorização do trabalho efetuado. Relativamente aos índices de produtividade percebemos que são difíceis de quantificar, no entanto, e de um modo geral esta aumentou em valores pouco significativos, cerca de 2,3%. ABSTRACT: The information Technology as a management tool can contribute to the healthy development of the organization. This fact has become visible by the interest showed on IT by the management body of the Health Services. On the implementation process of the IT Services the economy of information assumes a major role as a powerful and altering force to the landscape. ln this thesis we studied the IT services used by the Radiology Service of the Hospital Curry Cabral, and tried to understand how the professionals work, by using and improving the information on those systems. We analyze the productivity using markers built for the specified service, before and after the implementation of the IT Services to understand how far into the "IT Economics" we have traveled. Thru a direct approach a study was conducted using a questionnaire, and a target audience of 55 local radiology professionals, namely 17 radiology doctors, 6 service secretaries and 31 radiology technicians. ln general, the data gathered by this investigation, allowed us to verify that the data collected and updated by the Radiology professionals, is carefully collected, especially by the Radiology Technicians. We have also found that generally all Hospital professionals see the IT Services as a major help for management mainly thru better monitoring of accomplished work. ln relation to the productivity indexes we have found that they are hard to quantify, because certain aspects are close to impossible to ascertain, but in gross it has grown but in less than expected, more or less 2,3%.
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A preocupação com a qualidade dos serviços prestados pelas organizações de saúde é uma realidade. Em resultado de várias pressões e diferentes metodologias têm sido implementadas nas instituições Sistemas de Informação a fim de melhorar a qualidade e segurança dos procedimentos aí desenvolvidos. A qualidade dos Sistemas de Informação assume um destaque pela sua componente de mais-valia, neste trabalho procuramos avalia-la e verificar a sua correta implementação. A presente dissertação reporta-se ao estudo dos Sistemas de informação no Serviço de Radiologia do HCC, tendo como objetivo principal saber se os Sistemas de Informação, potenciaram a melhoria da qualidade de desempenho dos profissionais de saúde, assim como caracterizar a qualidade dos Sistemas de Informação. Como estratégia de pesquisa optamos por um estudo de natureza descritiva, utilizando um modelo de análise quantitativo. Aplicou-se um questionário elaborado pela investigadora, tendo sido aceites as respostas de 55 questionários realizados aos utilizadores dos SI. De uma forma geral os resultados demonstram que os Sistemas de Informação foram bem aceites por parte dos profissionais deste serviço, existindo porem algumas deficiências que não permite que se atinja níveis de qualidade elevados. Relativamente à formação depreendemos que existem algumas lacunas relativas ao processo de formação dos utilizadores, que podem ser colmatadas por uma intervenção adequada. ABSTRACT: The concern about the quality of the accounted services by the health organizations is a reality. Information Systems have been installed in many establishments as a result of many pressures and different methodologies in order to improve the quality and safety of the procedures developed in such places. The quality of the Information Systems gains relevance due to its “rise” character; on this essay we aimed to evaluate and verify its adequate execution. The present essay is about the study of the Information Systems on the Radiology Service of Hospital Curry Cabral (HCC) being its main objective to know if the Information Systems improved the performance of the health professionals, as well as to point out their quality. We decided to build a study of descriptive nature using a quantitative analysis method. We applied an inquiry elaborated by the researcher and accepted the answers of 55 inquiries made to the SI users. In general, the results revealed that the Information Systems were well accepted by the professionals of this service. However, some minor problems do not allow high standard of quality to be obtained. As regards training we understand that there are a few defaults concerning the process of formation of the users which can be surpassed if using an adequate intervention.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
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Mode of access: Internet.
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This article analyzes Boys in white: student culture in medical schoolby Howard S. Becker, Blanche Geer, Everett C. Hughes and Anselm Strauss, considered a model of qualitative research in sociology. The analysis investigates the trajectories of the authors, the book, qualitative analysis, and the medical students, emphasizing their importance in the origins of medical sociology and the sociology of medical education. In the trajectory of the authors, bibliographical information is given. The trajectory of qualitative research focuses on how this methodology influences the construction of the field. The investigation of the students' trajectory shows how they progress through their first years at medical school to build their own student culture.
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The 2005 National Institutes of Health (NIH) Consensus Conference proposed new criteria for diagnosing and scoring the severity of chronic graft-versus-host disease (GVHD). The 2014 NIH consensus maintains the framework of the prior consensus with further refinement based on new evidence. Revisions have been made to address areas of controversy or confusion, such as the overlap chronic GVHD subcategory and the distinction between active disease and past tissue damage. Diagnostic criteria for involvement of mouth, eyes, genitalia, and lungs have been revised. Categories of chronic GVHD should be defined in ways that indicate prognosis, guide treatment, and define eligibility for clinical trials. Revisions have been made to focus attention on the causes of organ-specific abnormalities. Attribution of organ-specific abnormalities to chronic GVHD has been addressed. This paradigm shift provides greater specificity and more accurately measures the global burden of disease attributed to GVHD, and it will facilitate biomarker association studies.
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Universidade Estadual de Campinas. Faculdade de Educação Física
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Universidade Estadual de Campinas . Faculdade de Educação Física
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Universidade Estadual de Campinas . Faculdade de Educação Física
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We present the genome sequences of a new clinical isolate of the important human pathogen, Aspergillus fumigatus, A1163, and two closely related but rarely pathogenic species, Neosartorya fischeri NRRL181 and Aspergillus clavatus NRRL1. Comparative genomic analysis of A1163 with the recently sequenced A. fumigatus isolate Af293 has identified core, variable and up to 2% unique genes in each genome. While the core genes are 99.8% identical at the nucleotide level, identity for variable genes can be as low 40%. The most divergent loci appear to contain heterokaryon incompatibility ( het) genes associated with fungal programmed cell death such as developmental regulator rosA. Cross-species comparison has revealed that 8.5%, 13.5% and 12.6%, respectively, of A. fumigatus, N. fischeri and A. clavatus genes are species-specific. These genes are significantly smaller in size than core genes, contain fewer exons and exhibit a subtelomeric bias. Most of them cluster together in 13 chromosomal islands, which are enriched for pseudogenes, transposons and other repetitive elements. At least 20% of A. fumigatus-specific genes appear to be functional and involved in carbohydrate and chitin catabolism, transport, detoxification, secondary metabolism and other functions that may facilitate the adaptation to heterogeneous environments such as soil or a mammalian host. Contrary to what was suggested previously, their origin cannot be attributed to horizontal gene transfer ( HGT), but instead is likely to involve duplication, diversification and differential gene loss (DDL). The role of duplication in the origin of lineage-specific genes is further underlined by the discovery of genomic islands that seem to function as designated ""gene dumps'' and, perhaps, simultaneously, as "" gene factories''.
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The presence of bacteria in the midgut of mosquitoes antagonizes infectious agents, such as Dengue and Plasmodium, acting as a negative factor in the vectorial competence of the mosquito. Therefore, knowledge of the molecular mechanisms involved in the control of midgut microbiota could help in the development of new tools to reduce transmission. We hypothesized that toxic reactive oxygen species (ROS) generated by epithelial cells control bacterial growth in the midgut of Aedes aegypti, the vector of Yellow fever and Dengue viruses. We show that ROS are continuously present in the midgut of sugar-fed (SF) mosquitoes and a blood-meal immediately decreased ROS through a mechanism involving heme-mediated activation of PKC. This event occurred in parallel with an expansion of gut bacteria. Treatment of sugar-fed mosquitoes with increased concentrations of heme led to a dose dependent decrease in ROS levels and a consequent increase in midgut endogenous bacteria. In addition, gene silencing of dual oxidase (Duox) reduced ROS levels and also increased gut flora. Using a model of bacterial oral infection in the gut, we show that the absence of ROS resulted in decreased mosquito resistance to infection, increased midgut epithelial damage, transcriptional modulation of immune-related genes and mortality. As heme is a pro-oxidant molecule released in large amounts upon hemoglobin degradation, oxidative killing of bacteria in the gut would represent a burden to the insect, thereby creating an extra oxidative challenge to the mosquito. We propose that a controlled decrease in ROS levels in the midgut of Aedes aegypti is an adaptation to compensate for the ingestion of heme.
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The T cell immunoglobulin mucin 3 (Tim-3) receptor is highly expressed on HIV-1-specific T cells, rendering them partially ""exhausted'' and unable to contribute to the effective immune mediated control of viral replication. To elucidate novel mechanisms contributing to the HTLV-1 neurological complex and its classic neurological presentation called HAM/TSP (HTLV-1 associated myelopathy/tropical spastic paraparesis), we investigated the expression of the Tim-3 receptor on CD8(+) T cells from a cohort of HTLV-1 seropositive asymptomatic and symptomatic patients. Patients diagnosed with HAM/TSP down-regulated Tim-3 expression on both CD8(+) and CD4(+) T cells compared to asymptomatic patients and HTLV-1 seronegative controls. HTLV-1 Tax-specific, HLA-A*02 restricted CD8(+) T cells among HAM/TSP individuals expressed markedly lower levels of Tim-3. We observed Tax expressing cells in both Tim-3(+) and Tim-3(-) fractions. Taken together, these data indicate that there is a systematic downregulation of Tim-3 levels on T cells in HTLV-1 infection, sustaining a profoundly highly active population of potentially pathogenic T cells that may allow for the development of HTLV-1 complications.
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Background: RRP is a devastating disease in which papillomas in the airway cause hoarseness and breathing difficulty. The disease is caused by human papillomavirus (HPV) 6 or 11 and is very variable. Patients undergo multiple surgeries to maintain a patent airway and in order to communicate vocally. Several small studies have been published in which most have noted that HPV 11 is associated with a more aggressive course. Methodology/Principal Findings: Papilloma biopsies were taken from patients undergoing surgical treatment of RRP and were subjected to HPV typing. 118 patients with juvenile-onset RRP with at least 1 year of clinical data and infected with a single HPV type were analyzed. HPV 11 was encountered in 40% of the patients. By our definition, most of the patients in the sample (81%) had run an aggressive course. The odds of a patient with HPV 11 running an aggressive course were 3.9 times higher than that of patients with HPV 6 (Fisher's exact p = 0.017). However, clinical course was more closely associated with age of the patient (at diagnosis and at the time of the current surgery) than with HPV type. Patients with HPV 11 were diagnosed at a younger age (2.4y) than were those with HPV 6 (3.4y) (p = 0.014). Both by multiple linear regression and by multiple logistic regression HPV type was only weakly associated with metrics of disease course when simultaneously accounting for age. Conclusions/Significance Abstract: The course of RRP is variable and a quarter of the variability can be accounted for by the age of the patient. HPV 11 is more closely associated with a younger age at diagnosis than it is associated with an aggressive clinical course. These data suggest that there are factors other than HPV type and age of the patient that determine disease course.