Serum and placental plgf expression in women with different levels of hyperglycemia

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Stress distribution in delayed replanted teeth splinted with different orthodontic wires: a three-dimensional finite element analysis

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

The cosmetic dye quinoline yellow causes DNA damage in vitro

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Observation of the rare B-s(0)->mu(+)mu(-) decay from the combined analysis of CMS and LHCb data

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Crystal growth and photoluminescence of europium-doped strontium titanate prepared by a microwave hydrothermal method

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Effect of mesenchymal stem cells on movement and urination of rats with spinal cord injury

Cell therapy has frequently been reported as a possible treatment for spinal trauma in humans and animals; however, without pharmacologically curative action on damage from the primary lesion. In this study, we evaluated the effect of administering human adipose-derived stem cells (hADSC) in rats after spinal cord injury. The hADSC were used between the third and fifth passages and a proportion of cells were transduced for screening in vivo after transplantation. Spinal cord injury was induced with a Fogarty catheter no. 3 inserted into the epidural space with a cuff located at T8 and filled with 80 mu L saline for 5 min. The control group A (n = 12) received culture medium (50 mu L) and group B (n = 12) received hADSC (1.2 x 10(6)) at 7 and 14 days post-injury, in the tail vein. Emptying of the bladder by massage was performed daily for 3 months. Evaluation of functional motor activity was performed daily until 3 months post-injury using the Basso-Beattie-Bresnahan scale. Subsequently, the animals were euthanized and histological analysis of the urinary bladder and spinal cord was performed. Bioluminescence analysis revealed hADSC at the application site and lungs. There was improvement of urinary bladder function in 83.3% animals in group B and 16.66% animals in group A. The analysis of functional motor activity and histology of the spinal cord and urinary bladder demonstrated no significant difference between groups A and B. The results indicate that transplanted hADSC improved urinary function via a telecrine mechanism, namely action at a distance.

Coinfection by toxoplasma gondii and leishmania spp. in domestic cats (Felis catus) in State of Mato Grosso do Sul

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

The use of a mixture of somatic and culture filtrate antigens in the evaluation of the immune response to Paracoccidioides brasiliensis

Three Paracoccidioides brasiliensis antigens, namely a culture filtrate preparation, a somatic antigen and a mixture of equal parts of the two, were tested by two serological techniques against sera from patients with paracoccidioidomycosis, and in an in vivo delayed hypersensitivity model in mice. The antigen mixture was more sensitive than the two individual antigens for the evaluation of humoral and cellular immune response to P. brasiliensis, both in man and in experimental animals.

Early treatment of an intruded primary tooth: a case report

The report is about a case of total intrusion of a deciduous central incisor involving a male patient of 14 months of age. Repositioning of the intruded tooth was performed 20 minutes after the trauma, followed by placement with sutures. Clinical and radiographic monitoring performed after 1, 2, 4, 9, and 13 months showed normal characteristics. We emphasize the development of preventive programs promoting parental awareness of the importance of looking for prompt care, resulting in a better prognosis.

Comparison of droperidol and ondansetron prophylactic effect on subarachnoid morphine-induced pruritus

The prophylactic effect of ondansetron on subarachnoid morphine-induced pruritus is controversial, while evidence suggests that droperidol prevents pruritus. The aim of this study is to compare the effects of droperidol and ondansetron on subarachnoid morphine-induced pruritus. 180 ASA I or II patients scheduled to undergo cesarean sections under subarachnoid anesthesia combined with morphine 0.2mg were randomized to receive, after the child's birth, metoclopramide 10mg (Group I - control), droperidol 2.5mg (Group II) or ondansetron 8mg (Group III). Postoperatively, the patients were assessed for pruritus (absent, mild, moderate or severe) or other side effects by blinded investigators. Patients were also blinded to their group allocation. The tendency to present more severe forms of pruritus was compared between groups. NNT was also determined. Patients assigned to receive droperidol [Proportional odds ratio: 0.45 (95% confidence interval 0.23-0.88)] reported less pruritus than those who received metoclopramide. Ondansetron effect was similar to metoclopramide [Proportional odds ratio: 0.95 (95% confidence interval 0.49-1.83)]. The NNT for droperidol and ondansetron was 4.0 and 14.7, respectively. Ondansetron does not inhibit subarachnoid morphine-induced pruritus.

Regulation of cardiac microRNAs induced by aerobic exercise training during heart failure

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Clareamento dentário x autoestima x autoimagem

Dental changes that compromise facial harmony can have serious consequences on the social image of the patient. Depending on the emotional significance for the individual it can change interpersonal relationships, causing profound changes in their patterns of self-acceptance and self-image, with profound effects on their self-esteem of the patient. The search for tooth whitening as cosmetic factor for a harmonic smile grew sharply in the last decade. Although the color of the tooth represents only one aspect in the set of determinants of facial harmony, it is a strong factor because it is quickly perceived. This study aims to report the clinical case of a patient with spots on their upper central incisors. For the patient these spots have compromised her smile, causing harm and discomfort in their everyday social and professional relationships.

Princípios de redução das fraturas panfaciais: revisão de literatura

Are called panfacial fractures when the upper, middle and lower facial thirds present fractures concurrently. In clinical practice, came to imply the involvement of two facial thirds. Panfacial fractures are usually accompanied by other systemic lesions that impair the patient's life and therefore require primary treatment. Almost invariably are associated with damage to soft tissues and severe losses of bone structures which may lead to severe facial deformations and malocclusions. The panfacial fractures treatment is complex because often there isn’t a stable bone structure to guide the reduction of various fractures. Several orders of treatment have been proposed, but they are variations of the two classical approaches "bottom to top and inside-out" and "top to bottom and out-inside". The aim of this paper is to discuss the principles of management and panfacial fractures treatment, emphasizing the sequence of fracture reduction and highlighting its indications, advantages and disadvantages, through literature review and reports of surgical clinic cases. We conclude that the exact sequence of fracture reduction is not as important as developing a treatment plan that allows accurate positioning of the fractured segments.

Pertubation du développement d'une incisive permanente incluse due à un traumatisme de la dent primire

Les anomalies du développement des dents permanentes peuvent être dues à un traumatisme des dents primaires, étant donné la proximité de la racine des dents primaires avec les dents permanentes sous-jacentes. Nous décrivons le cas d'un garçon de 14 mois qui a été dirigé vers la clinique pédiatrique de l'École de médecine dentaire de l'Universidad Estadual Paulista d'Araçatuba, au Brésil, après avoir subi un grave traumatisme qui a causé l'intrusion de l'incisive centrale droite primaire. L'examen radiographique réalisé 4 ans après le traumatisme a révélé un changement morphologique évolutif dans le germe de la dent permanente. Au moment de son éruption, l'incisive centrale permanente présentait une malformation coronaire avec hypoplasie de l'émail. Nous avons conclu qu'un suivi radiographique est indiqué après un traumatisme afin de surveiller les séquelles qui peuvent survenir dans les dents permanentes, même avant leur éruption.