Auto-referência de sintomas de lesões músculo-esqueléticas ligadas ao trabalho LMELT numa grande empresa em Portugal

RESUMO - A dor, incómodo ou desconforto ao nível músculo-esquelético, sobretudo devido a situações e/ou postos de trabalho com elevadas exigências ao nível postural, de aplicação de força, de repetitividade ou por incorrecta distribuição das pausas, é aceite como um indicador de situações de risco passíveis de se encontrarem na génese de lesões músculo- -esqueléticas ligadas ao trabalho (LMELT) (Stuart-Buttle, 1994). No sentido de avaliar a prevalência de sintomas de LME, efectuou-se um estudo numa grande empresa da indústria de componentes para automóveis na região de Lisboa durante o ano de 2001. Utilizou-se um instrumento de recolha de informação construído a partir de uma adaptação do questionário nórdico músculo-esquelético (QNM) (Kuorinka et al., 1987). Com o apoio do serviço de saúde ocupacional da referida empresa, o questionário foi entregue a todos os trabalhadores, obtendo-se uma taxa de respondentes de 63,2% (n = 574). A população em estudo é maioritariamente do sexo feminino (83,9%), tem idades compreendidas entre os 18 e os 65 anos e a classe modal situa-se entre os 26 e os 33 anos (23,3%). Os resultados evidenciam uma alta prevalência de sintomatologia de LME e diferenças significativas de sintomas entre as categorias profissionais (1) operadores de máquina de costura, (2) trabalhadores dos armazéns e de transporte de mercadorias e (3) trabalhadores da logística, qualidade e escritórios. Os operadores apresentam índices superiores e diferentes (p < 0,05) de sintomatologia nos últimos doze meses ao nível da região cervical, ombros, cotovelos, ancas/coxas, pernas/joelhos e tornozelos/pés e nos punhos nos últimos sete dias. No presente estudo, a análise dos dados obtidos parece indicar que a natureza e as características da actividade de trabalho do grupo profissional operadores de máquina de costura (flexão cervical > 20°, trabalho muscular predominantemente estático ao nível da articulação dos ombros, elevação dos membros superiores > 45°, ortostatismo e exigências elevadas ao nível dos punhos/mãos) estão implicadas no desencadear da sintomatologia auto- -referida.

Identifying finger postures when interacting with the touch screen of mobile devices

This study presents the results of preliminary test on the interaction between fingertip and touch screen. The objective of this study is to identify the fingertip posture when interacting with touch screen devices. Ten participants, 7 males and 3 females, participated in this study. The participants were asked to touch targets on the mobile devices screen by tapping them sequentially and connecting them. The participants performed the tasks in a sitting posture. A tablet with 10 inches screen and a mobile phone with 4 inches screen were used in the study. The results showed that all participants dominantly used their thumb to interact with the mobile phone in single and two hands postures. The common thumb posture adopted by the participants is the combination of the 60° pitch and 0° roll angles. While for interaction with tablet in various postures observed in the study, the participants commonly used their index fingers in the combination of 60° pitch and 0° roll angles. This study also observed the participant with long finger nails touched targets on the mobile devices screen by using her index or middle fingers very low pitch.

Search for massive supersymmetric particles decaying to many jets using the ATLAS detector in pp collisions at s√=8TeV

Results of a search for decays of massive particles to fully hadronic final states are presented. This search uses 20.3 fb−1 of data collected by the ATLAS detector in s√=8TeV proton--proton collisions at the LHC. Signatures based on high jet multiplicities without requirements on the missing transverse momentum are used to search for R-parity-violating supersymmetric gluino pair production with subsequent decays to quarks. The analysis is performed using a requirement on the number of jets, in combination with separate requirements on the number of b-tagged jets, as well as a topological observable formed from the scalar sum of the mass values of large-radius jets in the event. Results are interpreted in the context of all possible branching ratios of direct gluino decays to various quark flavors. No significant deviation is observed from the expected Standard Model backgrounds estimated using jet-counting as well as data-driven templates of the total-jet-mass spectra. Gluino pair decays to ten or more quarks via intermediate neutralinos are excluded for a gluino with mass mg~<1TeV for a neutralino mass mχ~01=500GeV. Direct gluino decays to six quarks are excluded for mg~<917GeV for light-flavor final states, and results for various flavor hypotheses are presented.

Desenvolvimento de um modelo de rotatividade numa indútria do setor Metalomecânico

Dissertação de mestrado em Engenharia Humana

Comparação entre métodos de avaliação do risco de desenvolvimento de lesões musculoesqueléticas nas extremidades distais dos membros superiores: um estudo em trabalhos de montagem manual

Dissertação de mestrado em Engenharia Humana

Relacionamentos em MMORPGs: online e offline

Dissertação de mestrado em Comunicação, Arte e Cultura

Diagnosis and therapeutics of pulmonary arteriovenous fistula in childhood. Case report and review of the literature

We report the case of a 3-year-old female patient, who, since birth, had cyanosis difficult to explain with usual diagnostic tests. The only findings on physical examination were cyanosis and clubbing of her fingers. Chest computerized tomography showed images of excessive attenuation in the right lung, which resembled arteriovenous fistulae that were later confirmed on cardiac catheterization. The fistulous trajectories were then embolized with 7 Gianturco coils, which resulted in an immediate increase in the arterial saturation of blood oxygen.

Monitorização do risco de dificuldades de aprendizagem específicas na leitura de alunos do 2.º ao 4.ºano no contexto do modelo de resposta à intervenção

Dissertação de mestrado em Educação Especial (área de especialização em Dificuldades de Aprendizagem Específicas)

Influence of oxygen conditions on bacterial interactions within biofilms related with cystic fibrosis

Dissertação de mestrado em Bioengineering

Contribuição para o melhoramento da gestão operacional de uma linha de fabrico de garrafas de gás

Dissertação de mestrado integrado em Engenharia e Gestão Industrial

Characterization of microbial populations in a wastewater treatment plant focusing on Staphylococcus aureus and Pseudomonas aeruginosa

Dissertação de mestrado em Bioengenharia

Procesos fotofísicos y fotoquímicos en sistemas organizados

Se estudiará el comportamiento de moléculas sonda aromáticas flourescentes en micelas inversas de AOT y BHDC y en soluciones de polielectrolitos y mezclas de polielectrolitos y detergentes. Se espera obtener información sobre la estructura de los sistemas microheterogéneos y cómo esta estructura afecta la formación de iones radicales obtenidos a partir de reacciones entre moléculas sonda y moléculas donoras o aceptoras de electrones. Las técnicas a emplear incluyen espectroscopía de absorción y emisión, láser flash fotólisis, flourescencia pulsada por láseres y time correlated single photon counting. Objetivos generales y específicos: 1. Fotofísica y fotoquímica en micelas inversas. 1.1. Exciplejos en micelas inversas. 1.2. Rendimientos de estados electrónicos triplete en micelas inversas. 1.3. Comportamiento de ftalocianinas y porfirinas en micelas inversas. 2. Soluciones de polielectrolitos y mezclas de polielectrolitos con detergentes. 2.1. Reacciones fotoinducidas. 2.2. Comportamiento de derivados de porfirinas y ftalocianinas. 3. Montaje de la técnica de Time Correlated Single Photn Counting. 4. Montaje de un equipo adicional de laser flash fotólisis. 5. Síntesis de derivados solubles en agua de porfirinas y ftalocianinas.

Disposición plasmática y residuos tisulares de marbofloxacina en truchas arco iris (oncorhynchus mykiss) en condiciones estivales e invernales. Plasmatic disposition and tissue residues of marbofloxacin in rainbow trouts (oncorhynchus mykiss) in summer and winter conditions

Los sistemas intensivos de producción, predisponen en los peces a la presentación de diversas enfermedades, lo que demanda el empleo de antimicrobianos para mantener la salud de los lotes de cultivo. En tal sentido es importante contar con información local en cuanto al comportamiento cinético a los efectos de determinar una adecuada dosificación de los antimicrobianos empleados y con esta información, establecer los periodos de resguardo necesarios para evitar la presencia violativa de estos fármacos en el animal destinado a consumo humano. En el presente proyecto se propone efectuar un estudio farmacocinético de concentraciones plasmáticas y tisulares alcanzadas y establecer los periodos de resguardo para marbofloxacina, antimicrobiano del cual no se tienen antecedentes regionales en cuanto a su disposición a diferentes temperaturas como las que condicionan las estaciones de verano e invierno, de marcada variación en la provincia, modificando la actividad metabólica de los peces. La concreción de este proyecto permitirá entregar conocimientos concretos y de aplicación directa en la cría intensiva de la trucha arco iris (Oncorhynchus mykiss) en diferentes condiciones ambientales, al contarse con la información necesaria para una adecuada dosificación y periodos de resguardo necesarios para evitar el residuo de este fármaco. Además, permitirá consolidar una línea de investigación dentro de la acuicultura muy poco desarrollada actualmente en el país. Intensive production systems predispose fishes to diverse diseases, which demands antimicrobial use for health maintenance in the lots of culture. In such sense it is important to have local information of the kinetic behavior to determine a suitable dosing of the antimicrobials employed, and on this information, to establish withdrawal periods to avoid the violative presence of these drugs in animals for human consumption. The present project will carry out a pharmacokinetic study of plasmatic and tissue concentrations to establish the withdrawal period for marbofloxacin, being known that temperature, modify the metabolic activity of the fish, and there are no local antecedents of disposition at different temperatures in summer and winter for this antimicrobial. The concretion of this project will allow to give concrete knowledge of direct application in intensive production of rainbow trout (Oncorhynchus mykiss), in different environmental conditions, counting with the necessary information for a suitable dosification and withdrawal periods to avoid residues of this drug. In addition, it will allow to consolidate an investigation line in acuiculture, not much developed in our country.

Congenital Heart Disease as a Warning Sign for the Diagnosis of the 22q11.2 Deletion

Background: To alert for the diagnosis of the 22q11.2 deletion syndrome (22q11.2DS) in patients with congenital heart disease (CHD). Objective: To describe the main CHDs, as well as phenotypic, metabolic and immunological findings in a series of 60 patients diagnosed with 22q11.2DS. Methods: The study included 60 patients with 22q11.2DS evaluated between 2007 and 2013 (M:F=1.3, age range 14 days to 20 years and 3 months) at a pediatric reference center for primary immunodeficiencies. The diagnosis was established by detection of the 22q11.2 microdeletion using FISH (n = 18) and/or MLPA (n = 42), in association with clinical and laboratory information. Associated CHDs, progression of phenotypic facial features, hypocalcemia and immunological changes were analyzed. Results: CHDs were detected in 77% of the patients and the most frequent type was tetralogy of Fallot (38.3%). Surgical correction of CHD was performed in 34 patients. Craniofacial dysmorphisms were detected in 41 patients: elongated face (60%) and/or elongated nose (53.3%), narrow palpebral fissure (50%), dysplastic, overfolded ears (48.3%), thin lips (41.6%), elongated fingers (38.3%) and short stature (36.6%). Hypocalcemia was detected in 64.2% and decreased parathyroid hormone (PTH) level in 25.9%. Decrease in total lymphocytes, CD4 and CD8 counts were present in 40%, 53.3% and 33.3%, respectively. Hypogammaglobulinemia was detected in one patient and decreased concentrations of immunoglobulin M (IgM) in two other patients. Conclusion: Suspicion for 22q11.2DS should be raised in all patients with CHD associated with hypocalcemia and/or facial dysmorphisms, considering that many of these changes may evolve with age. The 22q11.2 microdeletion should be confirmed by molecular testing in all patients.

Insights into molecular mechanisms regulating the activity of multidomain proteins in living cells using FRET-FLIM

FRET-FLIM, ENERGY TRANSFER, LIFETIME, DECAY ASSOCIATED SPECTRUM, DAS, KINASE, MAGUKS, SINGLE PHOTON COUNTING, PICOSECOND-TIME RESOLVED FLUORESCENCE SPECTROSCOPY, GFP, CFP, YFP, TOPAZ, NANOMETER, MICROSCOPY, LYMPHOCYTES, LCK, SAP97