The Genome of Anopheles darlingi, the main neotropical malaria vector

Anopheles darlingi is the principal neotropical malaria vector, responsible for more than a million cases of malaria per year on the American continent. Anopheles darlingi diverged from the African and Asian malaria vectors ∼100 million years ago (mya) and successfully adapted to the New World environment. Here we present an annotated reference A. darlingi genome, sequenced from a wild population of males and females collected in the Brazilian Amazon. A total of 10 481 predicted protein-coding genes were annotated, 72% of which have their closest counterpart in Anopheles gambiae and 21% have highest similarity with other mosquito species. In spite of a long period of divergent evolution, conserved gene synteny was observed between A. darlingi and A. gambiae. More than 10 million single nucleotide polymorphisms and short indels with potential use as genetic markers were identified. Transposable elements correspond to 2.3% of the A. darlingi genome. Genes associated with hematophagy, immunity and insecticide resistance, directly involved in vectorhuman and vectorparasite interactions, were identified and discussed. This study represents the first effort to sequence the genome of a neotropical malaria vector, and opens a new window through which we can contemplate the evolutionary history of anopheline mosquitoes. It also provides valuable information that may lead to novel strategies to reduce malaria transmission on the South American continent. The A. darlingi genome is accessible at www.labinfo.lncc.br/index.php/anopheles- darlingi. © 2013 The Author(s).

Soil and crop residue CO2-C emission under tillage systems in sugarcane-producing areas of southern Brazil

Appropriate management of agricultural crop residues could result in increases on soil organic carbon (SOC) and help to mitigate gas effect. To distinguish the contributions of SOC and sugarcane (Saccharum spp.) residues to the short-term CO2-C loss, we studied the infl uence of several tillage systems: heavy offset disk harrow (HO), chisel plow (CP), rotary tiller (RT), and sugarcane mill tiller (SM) in 2008, and CP, RT, SM, moldboard (MP), and subsoiler (SUB) in 2009, with and without sugarcane residues relative to no-till (NT) in the sugarcane producing region of Brazil. Soil CO2-C emissions were measured daily for two weeks after tillage using portable soil respiration systems. Daily CO2-C emissions declined after tillage regardless of tillage system. In 2008, total CO2-C from SOC and/or residue decomposition was greater for RT and lowest for CP. In 2009, emission was greatest for MP and CP with residues, and smallest for NT. SOC and residue contributed 47% and 41%, respectively, to total CO2-C emissions. Regarding the estimated emissions from sugarcane residue and SOC decomposition within the measurement period, CO2-C factor was similar to sugarcane residue and soil organic carbon decomposition, depending on the tillage system applied. Our approach may define new emission factors that are associated to tillage operations on bare or sugarcane-residue-covered soils to estimate the total carbon loss.

Damage Detection Based on Electromechanical Impedance Principle and Principal Components

This paper presents a novel time domain approach for Structural Health Monitoring (SHM) systems based on Electromechanical Impedance (EMI) principle and Principal Component Coefficients (PCC), also known as loadings. Differently of typical applications of EMI applied to SHM, which are based on computing the Frequency Response Function (FRF), in this work the procedure is based on the EMI principle but all analysis is conducted directly in time-domain. For this, the PCC are computed from the time response of PZT (Lead Zirconate Titanate) transducers bonded to the monitored structure, which act as actuator and sensor at the same time. The procedure is carried out exciting the PZT transducers using a wide band chirp signal and getting their time responses. The PCC are obtained in both healthy and damaged conditions and used to compute statistics indexes. Tests were carried out on an aircraft aluminum plate and the results have demonstrated the effectiveness of the proposed method making it an excellent approach for SHM applications. Finally, the results using EMI signals in both frequency and time responses are obtained and compared. © The Society for Experimental Mechanics 2014.

Jair Afonso Inácio, um pioneiro na preservação do patrimônio artístico brasileiro

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Referências étnicas africanas na moda brasileira contemporânea em duas leituras: Goya Lopes e Walter Rodrigues

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Na trilha da narrativa policial brasileira: Luiz Lopes Coelho e Rubem Fonseca

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Da inquisição à ficção: as narrativas do inquérito e os processos da escrita em António Vieira e Lobo Antunes

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Conselho às minhas amigas: os manuais de ciências domésticas de Júlia Lopes de Almeida (1896 e 1906)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Os jesuítas e a escravidão africana no Brasil colonial: um estudo sobre os escritos de Antonio Vieira, André João Antonil e Jorge Benci: sécs. XVII e séc. XVIII

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Relato e realidade nas cartas brasileiras do Padre Antônio Vieira: uma visão cognitivista e cultural

Pós-graduação em Linguística e Língua Portuguesa - FCLAR

Da ortografia para a fonética e a fonologia nos Sermões do Padre Antônio Vieira

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

A oralidade em Luuanda de Luandino Vieira e Alexandree outros heróis de Graciliano Ramos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Loucura: a temática que constrói o discurso da obra Hospício é Deus, de Maura Lopes Cançado

Pós-graduação em Letras - FCLAS

A vida moderna (1907-1922), o periódico-vitrine da cidade de São Paulo: tempos de modernidade com um leve toque português

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)