Modulation of HJURP (Holliday Junction-Recognizing Protein) Levels Is Correlated with Glioblastoma Cells Survival

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Estudo Psicológico de um Caso de Distúrbio de Linguagem

Our intention was to describe the case of a six-year-old boy, carrier of a language disturbance associated to neurological disorders, in language therapy. Our goal was to build instruments for the diagnosis of similar cases. Relating the patient's psychopathological characteristics with a neurological disease, we understood that both results in manifestations of verbal and physical aggressiveness as well as in the severe disturbance of the language. We hope we have contributed to the understanding of the disturbances of communication associated to psychogenic symptoms and of neurological disorders.

Relaciones entre tendencias de juicio moral, estilos de resolución de conflictos y percepción de la manifestación de la agresividad en niños y adolescentes

The moral judgment was approached upon a constructivist perspective which focuses on its evolution according to the different types of social relations. The several forms of resolution of conflicts are also considered in this reference, since they are related to situations of interaction, as well as the aggressiveness. The research was carried out with sixty children and teenagers from a socio-educational institution. It aimed to identify the variations according to age, and relate the trends in moral judgment, the styles of resolution of conflicts, and the perception of the educators regarding to the manifestation of aggressive behaviors. The instruments for collecting data were the Scale of Perception from Teachers for children that manifested Aggressive Behaviors in School, a Clinical Interview about moral judgment and the adaptation of the Children\'s Action Tendency Scale - CATS. The results showed that variations in relation to age were significant regarding to moral judgment. The younger children showed more heteronomous judgments and the older children more autonomous. Furthermore, the data evidenced a positive relationship between semiautonomia and aggressiveness, which raises the possibility of this being regarded as one of the unique strategies to take a position within an authoritarian and coercive environment.

Violência, imaginário e educação escolar: um olhar antropológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Interferência da torcida na ansiedade e agressividade de atletas adolescentes

O presente trabalho surge em função de buscar um melhor entendimento sobre o papel da torcida, diante dos estados emocionais dos atletas, em especial da ansiedade e da agressividade. Baseado em vasta revisão de literatura, que apresenta as diversas concepções conceituais aqui estudado (adolescência, agressão, ansiedade e torcida) e seus desdobramentos, o estudo assume a vertente da pesquisa qualitativa, optando pela pesquisa participante, como estratégia de verificação. Assim, interessou-se em estudar os aspectos relativos à ação da torcida e sua interferência no comportamento agressivo e ansioso do jogador jovem, que participa de uma modalidade federada, afim de verificar se o aumento da ansiedade e da agressividade, no momento esportivo, reflete o aumento de pressão que se exerce exteriormente. Considerou-se torcida aquele público presente, que assiste aos confrontos esportivos, nas figuras de pais, fãs, familiares e crônica esportiva e o público ausente, como os pais e a imprensa, que ficam no aguardo do resultado, em seus ambientes próprios. Esta pesquisa, exploratória, analisou o contexto esportivo competitivo de atletas das modalidades de basquetebol, futebol de salão, voleibol, handebol, atletismo e natação, observando, entrevistando e coletando falas e expressões que pudessem, após rigorosa categorização, oferecer subsídios para um replanejamento na conduta esportiva de adolescentes. Constatou a grande influência do público, em especial a dos pais, com muito determinismo, seguido do profissional da área esportiva, conforme indicam outros estudos. Explicita a questão da causa efeito no que diz respeito a ansiedade e agressão, oferecendo propostas para trabalhos que possibilitem outra abordagem ou favoreçam outras interferências por parte do público presente.

Therapeutic Delivery of miR-200c Enhances Radiosensitivity in Lung Cancer

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Influência de contaminante ambiental em tumor de mama em cadela

Mammary cancer is a multifactorial disease that is believed to be caused by genetic and environmental factors. Among the environmental factors, pyrethroids appear to be able to participate in carcinogenesis through several mechanisms, and have been shown to be associated to mammary tumors in canines. In order to investigate the possible rule of pyrethroid on DNA lesion in mammary tissue we compare the comet assay results between mammary tumor bearing dogs with and without pyrethroid associated to the peri mammary adipose tissue or the tumor itself. The pyrethroids presence was assessed by High Performance Liquid Chromatography (HPLC) and the DNA damage was assessed by the comet assay as previously described. Despite of correlation between DNA damage and tumor histologic aggressiveness, association between the severity of DNA damage and different types of mammary carcinoma was not found. Although pyrethroids were present in 22% of tumors and peritumoral adipose tissue, no difference in the degree DNA damage between the exposed and non exposed cells to pyrethroids were found. As future perspectives for this work, our group will evaluate the relationship of pyrethroids presence in tumors with its angiogenic potential. Angiogenesis evaluation will be based on presence of vascular endothelial growth factor (VEGF) in the tumor cells, and microvessel counts

Aspectos reprodutivos e sociais e resistência óssea em ratos machos submetidos ao exercício físico e/ou a um anabolizante esteróide

Nowadays the regular practice of sports is known as a way to obtain a better quality of life. On the other hand, the media has been distorting this idea, determining the ideal body as the hypertrophy phenotype. It is well known that the genetic factor does not allow all individuals to have this body shape. Besides the fact that, the anxiety of these people in obtain quick results, as one of the globalization’s consequence, make use of anabolic steroid to achieve this goal. However the bodybuilding or the strength muscle gain, make anabolic steroids users abuse and in major cases the users do not know the side effects. In front of these considerations, the present study evaluated the effects of the treatment with anabolic steroids and/or high intensity physical training on the corporal developing, the reproductive organs, bone parameters (strength and bone deformation) and seminal parameters as well the social behavior (aggressiveness). In other to obtain the experimental group, male Wistar rats were used, with 75 days old. The groups were divided into: Vehicle Non-Training (NV), Anabolic Steroid-Non-Training (NA), Vehicle-Training (TV) and Anabolic Steroid-Training (TA). These rats received i.m. injections, twice a week, of anabolic steroid (5mg/kg per animal of nandrolona decanoate) or vehicle (the same volume of peanut oil per animal) and the group TV and TA were submitted to physical training three times per week, during eight weeks. The body mass, wet weight of reproductive organs, femur and semen of the different groups were measured. The aggressive test was also realized in two steps: the first, within 4 weeks of the treatment and the other step in the end of the treatment, in this period the animal was isolated. It was not observed alterations in body mass of the groups. Though it was observed a benefic effect on the maximum strength of the... (Complete abstract click electronic access below)

Vocalizações de Dendropsophus nanus (Anura: Hylidae) e a modulação de comportamento ante estímulos acústicos

The aim of this study is to analyze the vocalizations of Dendropsophus nanus and its responses to the dominant frequencies of conspecific calls. There were made playback experiments by broadcasting calls of different dominant frequencies towards particular individuals, while their behavioral responses were registered. The results suggest that the playbacks cause behavioral complexity and aggressiveness to increase.

Estudo de repelência com diversos produtos de origem natural em operárias de Apis mellifera em semi-campo

Accidents involving insects of the Hymenoptera order occur very often with both human beings and domestic pets and, in Brazil, they include aggravated cases with Africanized bees (Apis mellifera). The aggravation of deforestation and the lack of awareness regarding the subject are factors that contribute to the rise of the number of bees in the urban environment. This fact has been causing several derangements among the population because, once these insects are bothered, they become very aggressive. Considering the risks to population and the great amount of accidents that could be avoided, the development of researches with the goal of determining repelling substances is rather important. Therefore, this research evaluated the repelling action of essential natural oils obtained from rosemary (Rosmarinus oficinalis), lemongrass (Cymbopogon citratus), thyme (Thymus vulgaris), cedar (Juniperus virginiana), clove (Syzygium aromaticum) and mint (Mentha piperita) on A. mellifera Africanized worker bees in both semi-field and aggressiveness tests. Among the evaluated composites, the lemongrass, mint and clove essential natural oils presented a grater repelling effect, inhibiting the bees’ visitation to the managed feeders almost completely. The cedar essential natural oil was the least effective composite, and the rest of the tested oils presented satisfactory repellency, which became less effective over time, according to non-parametric Mann-Whitney test. However, further tests showed that only the lemongrass essential natural oil caused a less aggressive response from the bees, which can confirm the repelling power of this composite. This way, according to the results obtained through this research, lemongrass presents a greater potential to the development of effective repelling formulas against Africanized bees (Apis mellifera)

Agressividade infantil: análises de artigos científicos

This project has its topic on child aggression. Child aggression has always been present in the school environment. Therefore, aggressive behaviors have been interpreted as violence in which the educators have come to complaining earlier now. This study has its objective to survey published articles in electronic magazines, which talk about thematic aggression, child aggression and to systemize and analyze these procedures. Therefore, there will be a survey on the articles about this set of themes based on the data from Scielo (Scientific Electronic Library Online). In this data base, there are indexed published articles in electronic magazines from different areas of knowledge considered relevant. The articles will be identified by the keywords of aggressiveness, children, aggression, childhood, infantile, schools and their combinations

Social Stability Related to Sex Group Composition in the Cichlid Nile Tilapia

Aquaculture practices usually put the Nile tilapia in an artificial social environment, which males predominate due to their faster growth desirable for aquaculture purposes. Such a situation can increase male-male fighting because males are generally more aggressive than females, and also because fighting ability is similar within the same sex, leading to longer contests. As behavior has been used to infer welfare in several fish species, the aim of this study was to investigate whether sex composition affects agonistic interactions, social hierarchy and energetic demand in groups of Nile tilapia (Oreochromis niloticus; L.). Size-matched adult fish were divided in two treatments: MM = four males and MF = two males and two females (10 repetitions for each treatment). The experiment lasted for 11 days and social interactions (aggressiveness and rank order) were recorded at the 2nd, 6th and 10th days (15 min per day). Fish were food deprived and body weight loss was used to infer energetic cost. A higher frequency of lateral threat (Student’s t independent test; t = 2.55; p = 0.02) and total interactions (Student’s t independent test; t = -2.81; p = 0.01) was observed in the MF treatment. MM group showed unstable hierarchy (Binomial test, p = 0.04), which is considered a social stressor. However, mean weight loss was not affected by treatments (Student’s t independent test; t = -0.74; p = 0.47). These results support the idea that sexual composition affects aggressive interactions and destabilizes social hierarchy, but not energy cost

Masculinidades e violências em narrativas de vida de jovens em conflito com a lei

Pós-graduação em Psicologia - FCLAS

Expressão dos genes MDR-1, TP53, BCL-2 e BAX em tumor venéreo transmissível canino e sua relação com a agressividade e resposta à terapia

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Intervenções psicológicas no sistema familiar de adolescentes em liberdade assistida: relatos de experiência

This report comes from psychological appointments to families of teenagers within the socio-educational approach of Assisted Freedom. The interventions were carried out to give teenagers the pertaining feeling to a family back and to manage conflict situations. The method included interviews and home appointments with the whole family, appointments in family groups within the institution and also with an available psychological attendance for urgent and emergent matters. In the mediator psychologist view, getting along with the family decreased teenagers feelings of abandonment and also their negative actions. Study results demonstrated the relevance of the proposal to improve the quality of the relationship between adolescents with their family, school and society in which they belong.