990 resultados para swine anthrax


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Mode of access: Internet.

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Vols. <5-6> contain indexes of animals, owners, and breeders.

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Vol.-10 contain indexes of breeders, owners and animals.

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Vols. 11-13 contain indexes of owners, breeders, animals and stockholders.

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Printed: Peoria, Ill. : Duroc Bulletin Print., 1906-Mar. 1910; Peoria, Ill. : J.W. Franks & Sons, Printers, Sept. 1910- ; Des Moines, Iowa : Homestead Print. Co., -Dec. 1915; Peoria, Ill. : Brown Print. Co., Apr. 1915-Feb. 1916.

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Vol. 85 contains financial statement, constitution and by-laws of the National Duroc Record Association.

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Ceased publication.

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Vols. [18]- include indexes of animals and lists of transfers.

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Includes bibliographies.

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Edited by D. I. Eaton.

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The protective antigen (PA) of anthrax toxin binds to a cell surface receptor, undergoes heptamerization, and binds the enzymatic subunits, the lethal factor (LF) and the edema factor (EF). The resulting complex is then endocytosed. Via mechanisms that depend on the vacuolar ATPase and require membrane insertion of PA, LF and EF are ultimately delivered to the cytoplasm where their targets reside. Here, we show that membrane insertion of PA already occurs in early endosomes, possibly only in the multivesicular regions, but that subsequent delivery of LF to the cytoplasm occurs preferentially later in the endocytic pathway and relies on the dynamics of internal vesicles of multivesicular late endosomes.