Correlação de resultados da depuração de creatinina determinada e o Clearance estimado por fórmula

O presente trabalho compara os resultados obtidos da depuração da creatinina endógena de pacientes encaminhados por solicitação médica, realizados pelo Setor de Bioquímica Clínica do CRD-NAC Unesp com protocolo do procedimento de depuração implantado na rotina laboratorial, que utiliza dados da creatinina de sangue e urina (amostra de 24 horas), com os resultados obtidos, para os mesmos pacientes, a partir das fórmulas de Cockcroft-Gault, MDRD simplificada e CDK-EPI, onde não se utiliza os valores obtidos na amostra de urina de 24 horas. E, a partir dessa análise, verifica em que casos o resultado do exame sem a amostra de urina de 24 horas correlaciona-se com o resultado da depuração da creatinina endógena realizado como procedimento de rotina e quais seriam as prováveis variáveis interferentes na aplicação destas fórmulas utilizadas em casos específicos, conforme a necessidade na avaliação clínica.

Aparelho expansor Haas com molas digitais para correção da mordida cruzada anterior e posterior

As mordidas cruzadas anteriores e posteriores podem ser tratadas desde as dentaduras decídua e mista. Embora a literatura descreva diversas técnicas para a correção individualizada desses problemas, o tratamento de pacientes com as duas alterações é pouco documentado. O presente artigo relata o tratamento desses problemas com o expansor tipo Haas associado a molas digitais. Essa alternativa apresenta boa previsibilidade, fácil confecção e instalação, e ótima eficiência.

Detecção de Periodontopatógenos, Glicoproteína Emmprin (Cd-147) e sua correlação com MMP-2 e MMP-9

Periodontitis is an infectious disease characterized by the secretion of a variety of inflammatory mediators that lead to destruction of tooth supporting tissues, including the possible loss of alveolar bone, in association with infection with multiple species of bacteria. It is estimated that more than 400 species colonize the biofilm and some oral species related to periodontal disease is present in the subgingival including P. gingivalis, T. forsythia and T. denticola. However, other organisms may be related of this disease, as Filifactor allocis and Prevotella tannerae. These microorganisms and subproducts such as endotoxins released into the extracellular lead to the stimulation of metalloproteinase inducer glycoprotein (EMMPRIN, CD-147), which stimulates the release of MMPs by host cells, like fibroblasts and endothelial cells, thus leading to tissue destruction. The objective of this study was to detect F. allocis, P. tannerae, T. denticola and the glycoprotein EMMPRIN (CD-147) and its correlation with MMP-2 and MMP-9 in subgingival fluid samples of patients with chronic periodontitis. Fluids were collected from healthy and disease subgingival sites of 20 healthy individuals before basic periodontal treatment and after of 60 days of treatment. Their DNAs were extracted and portions of the 16S gene were amplified and performed conventional PCR. For immunological analysis and quantification of EMMPRIN (CD-147), MMP-2 and MMP-9 was used ELISA-Sandwich. Results demonstrated that the disease group showed significantly high amounts of T. denticola, F. alocis and P. tannerae when compared with health sites. MMP-2 and MMP-9 were detected in high concentrations with statistically significantly reduction after periodontal treatment to MMP-2, but without correlation with EMMPRIN.

Parâmetros físicos e químicos da água, balanço de massa e a ictiofauna de quatro microbacias hidrográficas do Sistema Paraíba do Sul e sua correlação com a geomorfologia regional

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Correlação e visualização de alertas de segurança em redes de computadores

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Imunofenótipos de linfócitos T no sangue e no liquor de cães com leishmaniose visceral: correlação com as lesões encefálicas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Prediction of genomic-enabled breeding values and genome-wide association study for feedlot average daily weight gain in Nelore cattle

Pós-graduação em Genética e Melhoramento Animal - FCAV

Rentabilidade na semeadura cruzada da cultura da soja

Soybean cross-seeding tillage came from better spatial arrangement of plants per area, so some producers have opted for this tillage system, which consists in seeding the area in two steps, forming a chessboard with perpendicular lines of tillage. This study aims to analyse the soybean productivity and production costs when it planted in different dispositions of crossed tillage. The experiment was conducted during the harvests 2011/2012 and 2012/2013 at Lageado Farm of the FCA/UNESP, Botucatu-SP, in an area cultivated under no-tillage. The experimental design was in randomized block with five treatments and eight replications. The treatments were: seeding in parallel rows with recommended fertilization and recommended plant population (conventional); cross-seeding with doubled fertilization and doubled plant population; cross-seeding with recommended plant population and doubled fertilization; cross-seeding with doubled plant population and recommended fertilization; cross-seeding with fertilization and recommended plant population. The results showed statistical difference among the treatments, with increased productivity for the cross-seeding with doubled plant population and recommended fertilization. However the conventional tillage with parallel lines shows higher net earnings than soybean cross-seeding, being more profitable for producer.

Avaliação dos constituintes proteicos do plasma seminal e da membrana plasmática se espermatozóides e sua correlação com a fertilidade de garanhões

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação e correlação da presença de endotoxinas e MMP-3, -8 e -9 em canais radiculares com necrose pulpar submetidos ao tratamento endodôntico - estudo in vivo

It is know that endotoxin and various matrix metalloproteinases (MMPs) are involved in the development of periapical lesions. The purpose of this study was to evaluate and correlate the presence of endotoxins and MMP- 3, MMP-8 and MMP-9 in root canals of teeth with necrotic pulp and periapical lesion before, during and after the biomechanical preparation (PBM) using a combination of different irrigations solutions and intracanal dressing. Thirty-three single-root teeth with a diagnosis of pulp necrosis and periapical lesion radiographically visible were selected. Immediately after the coronal opening was collected the first sample from the root canal content. Then, all canals were prepared (cervical and middle thirds) by oscillatory instruments (EndoEze) and irrigated by 2.5% NaOCl. After, a manual preparation was made for the apical third and the teeth were divided into three groups according to the irrigation protocol: G1) 2.5% NaOCl (4 manual files); G2) 2.5% NaOCl (2 manual files) + [Ca (OH)2 0.14%] (2 manual files) and G3) 2.5% NaOCl (2 manual files) + polymyxin B (2 manual files). After the PBM, the second sample was collected; then the third collect was performed after using EDTA final flush. The fourth sample was collected 14 days after placing the dressing [2% chlorhexidine gel + Ca(OH)2]. Quantification of endotoxins was performed by a kinetic chromogenic lysate from amoebocytes of Limulus (LAL) and quantification of MMPs by ELISA assay. The results were analyzed statistically by Kruskal-Wallis and Dunn's test (5%) and ordinal Spearman correlation. Presence of endotoxin was observed in 100% of cases and G3 showed the greatest reduction of endotoxins from the 1st to the 2nd samples (97%), being statistically similar to G2 (84.2%) and different from G1 (49.4%) (p<0.05). The intracanal dressing promoted a significant reduction of endotoxin, no difference among the groups. For...

Pistas diretas para o tratamento de mordida cruzada posterior

The malocclusions are one focus of discussions in public health, due to which it is necessary to incorporate correction procedures that are inexpensive, easy to perform and which can be made in health services. Planas Direct Tracks meet such characteristics which make them advantageous for the crossbite correction. The aim of this study was to present a case in which correction of unilateral crossbite was performed with the resources available in a public clinic. This is a 6 year-old patient who presented functional unilateral crossbite in canines and posterior teeth. A cross decreased maxillary arch leading to a condition of unilateral posterior crossbite was detected. Occlusal adjustments were performed in canine and posterior teeth; however it was not enough to restore the occlusal balance. It was decided to prepare Planas Direct Tracks in canines, allowing functional balance, which prevented masticatory movement alteration during the growth phase and malocclusion correction. Controls were performed every six months to evaluate the patient's progress and whether or not new occlusal adjustments were necessary. Monitoring and treatment were conducted for 5 years, until stabilization of the permanent dentition ensuring treatment. It is concluded that Planas Direct Tracks were effective for the correction of unilateral posterior crossbite. So, it is essential to note that this procedure can be performed in public services.

Mordida cruzada posterior, correccion y consideraciones: caso clínico con 7 años de seguimiento

Early treatment of functional unilateral posterior crossbite during the mixed dentition is extremely important for contemporary Orthodontics, provides the correct positioning of osseous bases, teeth and temporomadibular joint when the stomatognathic system is in growth and development. These results generally develop into an adequate craniofacial relationship, reducing the necessity for more complex treatments at permanent dentition. The subject of this paper was to report patient 8 years old, diagnosed with functional unilateral posterior crossbite, and was treated by an expander appliance type Quad-helix emphasizing the long-term stability. The malocclusion was corrected in 3 months of active use of the appliance, 3 months for retention purposes and followed up during 7 years post-treatment. The stability in long term of functional unilateral posterior crossbite treated is closely related with early diagnostic, the elimination of the etiological factor associated with a correct appliance and the mechanic of treatment.