Calculation of GFSR pseudorandom number binary starting matrix,

Mode of access: Internet.

A class of algorithms for automatic evaluation of certain elementary functions in a binary computer.

"Supported in part...under Grant No. US NSF GJ812 and Grant No. US NSF GJ813."

Generating binary trees lexicographically /

Bibliography: p. 26.

A prototype binary image scaling facility /

"UILU-ENG 84 1703"--Cover.

Consistent properties of composite formation under a binary relation,

"Supported by Contract AT (11-1)-1018 with the U.S. Atomic Engery Commission."

Computational experience in all-integer, binary variable, integer programming problems using Gomory's all-integer algorithm,

Bibliographical footnotes.

Two upper bounds for the weighted path length of binary trees.

Thesis (M.S.)--University of Illinois at Urbana-Champaign.

The electrochemical cell as a binary memory element /

Includes bibliographical references (leaves 132-134).

Methods of binary addition.

Includes bibliographical references.

Phase relationships in selected binary and ternary vanadium-base alloys systems

"Materials Laboratory, Contract No. AF33(616)-5771, Project No. 7021."

Theoretical comparison of binary data transmission systems,

"Prepared under the sponsorship of Rome Air Development Center, Air Research and Development Command, United States Air Force, Griffiss Air Force Base, New York, Advanced Development Laboratory. Contract no. AF 30 (602)-1702, project no. 4519, task no. 45232."

Research and development on the effects of high pressure and temperature on various elements and binary alloys,

"Materials Central, Contract no. 33(616)-5995. Project no. 7351.

A functional description of the Edvac [an automatically-sequence serial binary electronic digital computer. Final report of work under contract W36-034-ORD-7593 between the Ordinance Department, Department of the Army and the University of Pennsylvania, Moore School of Electrical Engineering.

Errata, as of Apr. 1, 1950 (7 ¹., 2 diagrs.) inserted.

Effects of carbon surface chemistry and solution pH on the adsorption of binary aromatic solutes

Adsorption of p-cresol, nitrobenzene and p-nitrophenol on treated and untreated carbons is investigated systematically. The effects of carbon surface chemistry and solution pH are studied and discussed. All adsorption experiments were carried out in pH-controlled solutions to examine the adsorption properties of the adsorption systems where the solutes are in molecular as well as ionic forms. Using the homogeneous Langmuir equation, the single solute parameters are determined. These parameters are then used to predict the binary solute adsorption isotherms and gain further insights into the adsorption process. (C) 2002 Elsevier Science Ltd. All rights reserved.

What is the best size descriptor to use for pharmacokinetic studies in the obese?

The prevalence of obesity in the western world is dramatically rising, with many of these individuals requiring therapeutic intervention for a variety of disease states. Despite the growing prevalence of obesity there is a paucity of information describing how doses should be adjusted, or indeed whether they need to be adjusted, in the clinical setting. This review is aimed at identifying which descriptors of body size provide the most information about the relationship between dose and concentration in the obese. The size descriptors, weight, lean body weight, ideal body weight, body surface area, body mass index, fat-free mass, percent ideal body weight, adjusted body weight and predicted normal body weight were considered as potential size descriptors. We conducted an extensive review of the literature to identify studies that have assessed the quantitative relationship between the parameters clearance (CL) and volume of distribution (V) and these descriptors of body size. Surprisingly few studies have addressed the relationship between obesity and CL or V in a quantitative manner. Despite the lack of studies there were consistent findings: (i) most studies found total body weight to be the best descriptor of V. A further analysis of the studies that have addressed V found that total body weight or another descriptor that incorporated fat mass was the preferred descriptor for drugs that have high lipophilicity; (ii) in contrast, CL was best described by lean body mass and no apparent relationship between lipophilicity or clearance mechanism and preference for body size descriptor was found. In conclusion, no single descriptor described the influence of body size on both CL and V equally well. For drugs that are dosed chronically, and therefore CL is of primary concern, dosing for obese patients should not be based on their total weight. If a weight-based dose individualization is required then we would suggest that chronic drug dosing in the obese subject should be based on lean body weight, at least until a more robust size descriptor becomes available.