The arts and sciences abridged : with a selection of pieces, from celebrated modern authors, calculated to improve the manners and refine the taste of youth: particularly designed and arranged for the use of schools /

Advertisements on p. [1]-[4] at end listing "School and classical books for sale at Charles Peirce's bookstore, Portsmouth, N.H."

The animal kingdom arranged in conformity with its organization,

"Catalogue of authors": v. 4, p. [429]-495.

Giffe's new male quartet book : a choice collection of new secular quartets for male voices /

Includes index.

New science of elocution. The elements and principles of vocal expression in lessons, with exercises and selections systematically arranged for acquiring the art of reading and speaking.

A revised edition of the author's Science of elocution cf. Pref.

The Documentary history of the state of New-York; arranged under direction of the Hon. Christopher Morgan, secretary of State.

Vol. 4 has imprint: Albany, C. Van Benthuysen, public printer.

The ideal : a collection of new music, consisting of duets, quartets, hymn-tunes, anthems, etc., together with a full and complete course of elementary instruction : designed for singing schools, musical institutes, conventions, etc. /

Mode of access: Internet.

Cortège : extrait de la Petite suite à 4 mains /

Part for violin.

Plays of Mr. William Shakespeare : as re-written or re-arranged by his successors of the restoration period as presented at the Dukes theatre and elsewhere circa 1664-1669; being the text of these so-restored plays with the First folio Shakespeare text, with critical introductions /

Edition of 250 sets. This set no. . Arbitrarily numbered to correspond with the set of the Bankside Shakespeare.

Fire insurance cases: being a collection of all the reported cases on fire insurance, in England, Ireland, Scotland, and America, from the earliest period to the present time, chronologically arranged ... with notes and references.

v. 1. 1729-1839.--v. 2. 1840-1848.--v. 3. 1849-1854.--v. 4. 1855-1864.--v. 5. 1865-1875.

Political pamphlets (United States) from the Durrett collection...1801-[1878] arranged chronologically.

Title page typewritten.

The British flora, or, Genera and species of British plants : arranged after the reformed sexual system : and illustrated by numerous tables, and dissections /

Collation: v.1: [2], x, 120 p.; v.2: 138, [2] p. (last leaf blank); v.3: 126, [2] p. (last leaf blank); v.4: 100 p.; v.5: 52 p.; v.6: (atlas): 347 leaves of plates.

Análise da imunoexpressão de Oct- 4 e C44 em lesões odontogênicas epiteliais benignas

benign epithelial odontogenic lesions are great clinical importance entities that develop in the jaws from the tissues that form teeth. It has been shown that in benign and malignant tumors, are present in a large number of tumor stem cells, which has great implications in the development of these lesions. Oct-4 and CD44 have been demos as important markers for tumoral stem cells. The objective of this study was to identify epithelial cells expressing stem cell markers by immunohistochemical expression of Oct-4 and CD44 in a series of cases of benign epithelial odontogenic lesions. The sample was comprised of 20 cases of odontogenic keratocyst (OKC), 20 cases of solid/multicystic ameloblastoma and 20 cases of adenomatoid odontogenic tumor (AOT). The expression of Oct-4 and CD44 was evaluated in epithelial lesions using the percentage of positive cells (PP) and the intensity of expression (IE), being realized the sum of these scores, resulting in Total Immunostaining Score (TIS) ranging 0 to 7. The results were submitted to the appropriate statistical test (nonparametric Kruskal-Wallis and Spearman correlation coefficient). All cases were positive for both markers and most showed high expression of both markers. The analysis of Oct-4 expression revealed no statistically significant differences (p = 0.406) among the studied lesions. Regarding the CD44 expression, there was a statistically significant difference between the cases of ameloblastoma and TOA in relation to the CCO, with the latter show more cases in the score 7 (p = 0.034). In the correlation analysis of the immunoreactivity of both markers in the three lesions studied, there was no statistically significant correlation. The results of this study identified the presence of cells with stemness characteristics arranged at various sites in the epithelial component of the studied lesions suggesting their possible role in the histogenesis and differentiation in benign epithelial odontogenic lesions, thus contributing to the development of these lesions.

Análise da imunoexpressão de Oct- 4 e C44 em lesões odontogênicas epiteliais benignas

benign epithelial odontogenic lesions are great clinical importance entities that develop in the jaws from the tissues that form teeth. It has been shown that in benign and malignant tumors, are present in a large number of tumor stem cells, which has great implications in the development of these lesions. Oct-4 and CD44 have been demos as important markers for tumoral stem cells. The objective of this study was to identify epithelial cells expressing stem cell markers by immunohistochemical expression of Oct-4 and CD44 in a series of cases of benign epithelial odontogenic lesions. The sample was comprised of 20 cases of odontogenic keratocyst (OKC), 20 cases of solid/multicystic ameloblastoma and 20 cases of adenomatoid odontogenic tumor (AOT). The expression of Oct-4 and CD44 was evaluated in epithelial lesions using the percentage of positive cells (PP) and the intensity of expression (IE), being realized the sum of these scores, resulting in Total Immunostaining Score (TIS) ranging 0 to 7. The results were submitted to the appropriate statistical test (nonparametric Kruskal-Wallis and Spearman correlation coefficient). All cases were positive for both markers and most showed high expression of both markers. The analysis of Oct-4 expression revealed no statistically significant differences (p = 0.406) among the studied lesions. Regarding the CD44 expression, there was a statistically significant difference between the cases of ameloblastoma and TOA in relation to the CCO, with the latter show more cases in the score 7 (p = 0.034). In the correlation analysis of the immunoreactivity of both markers in the three lesions studied, there was no statistically significant correlation. The results of this study identified the presence of cells with stemness characteristics arranged at various sites in the epithelial component of the studied lesions suggesting their possible role in the histogenesis and differentiation in benign epithelial odontogenic lesions, thus contributing to the development of these lesions.

Supporting Cubane’s Renaissance: Metathesis reactions on 4-iodo-1-vinylcubane and Stetter reaction on 1-iodocubane-4-carboxaldehyde

Cubane is a peculiar cube-shaped alkane molecule with a rigid, regular structure. This makes it a good scaffold, i.e. a molecular platform to which the substituents are arranged in a specific and fixed orientation. Moreover, cubane has a body diagonal of 2.72 Å, very similar to the distance across the benzene ring, i.e. 2.79 Å. Thus, it would be possible to use cubane as a scaffold in medicinal and material chemistry as a benzene isostere 1,2. This could lead to advantages in terms of solubility and toxicity and could provide novel properties. For this purpose, the possibility of performing “modern organic chemistry” on the cubane scaffold has to be studied. This project was entirely carried out in the framework of the Erasmus+ mobility programme at the Trinity College (Dublin, IRL) under the supervision of prof. M. O. Senge. The main goal of this project was to widen the knowledge on cubane chemistry. In particular, it was decided to test reactions that were never applied to the scaffold before, such as metathesis of 4-iodo-1-vinylcubane and Stetter reaction of 1-iodocubane-4-carboxaldehyde. These two molecules were synthesized in 10 and 9 steps respectively from commercially available cyclopentanone, following a known procedure. Unfortunately, metathesis with different olefins, such as styrene, α,β unsaturated compounds and linear α-olefins failed under different conditions, highlighting cubane behaves as a Type IV, challenging olefin under metathesis conditions. Even the employment of a specific catalyst for hindered olefins failed in the cross-coupling with linear α-olefins. On the other hand, two new molecules were synthesized via Stetter reaction and benzoin condensation respectively. Even if the majority of the reactions were not successful, this work can be seen as an inspiration for further investigation on cubane chemistry, as new questions were raised and new opportunities were envisioned.