[Colección de fotografías de Ayora] [Material gráfico]

[1-3]. Vistas panorámicas de Ayora (3 fot.) -- [4-6]. Vicenta Alarte Gómez, esposa de Juan Roglá Garrido, con vestido blanco con puntilla o con toquilla en el patio de la casa de Ayora, con palanganas, cepillo, tinaja, leña y también con macetas con flores (3 fot.) -- [7]. Vista general de la calle de la Marquesa en Ayora con carros y gente (1 fot.) -- [8]. Retrato de Facundo Roglá Alarte, Arcipreste de Torrent (1 fot.) -- [9] Facundo Rogla Alarte, sacerdote, en el huerto del patio de la casa (1 fot.) -- [10-11]. Retratos de grupo familiar de los Roglá Alarte junto a sacerdotes, entre ellos Facundo Roglá Alarte, en el patio de la casa con macetas con flores y parra (2 fot.) -- [12]. 8 retratos de José Roglá Alarte y miembros de su familia (1 fot.) -- [13]. Retrato de grupo familiar de los López Blat: Rosalia López Blat, con camisa rayada y toquilla, a sus derecha su madre; el niño de la izquierda es Francisco Roglá López con su hermana Amparo; la niña de arriba es Rosalia Roglá López (1 fot.) -- [14]. 8 retratos de Rosalia López Blat y miembros de su familia (1 fot.) -- [15]. Amparo y Rosalia Roglá López, 1900 (1 fot.) -- [16]. Pregonero tocando la corneta junto a labrador y niños con cántaro en la calle Empedrá de Ayora frente al número 20, casa de la familia Lliberós Roglá, la primera a la izquierda (1 par estereoscópico) (1 fot.) -- [17]. Entrada al pueblo de Ayora por la calle Mercadal con gente (1 fot.) -- [18-19]. El niño Francisco Roglá López en una casa de campo y con un cazador, 1900 (2 fot.) -- [20]. Casa de campo (1 par estereoscópico) (1 fot.) -- [21]. Grupo familiar comiendo una paella en la Ermita de la Virgen del Rosario de Ayora (1 fot.) -- [22]. Francisco Roglá López con su madre, hermanas y familia en el monte junto a un mojón con una bandera blanca (1 fot.) -- [23]. Rosalia López Blat con sus hijos, su hermana Carmen y familia en la montaña junto a un mojón con la inscripción: "vedado de caza", 1900 (1 fot.) -- [24]. El niño Francisco Roglá López con sombrero a la derecha de la imagen y Facundo Roglá Alarte el segundo por la derecha del grupo de sacerdotes (entre ellos José del Campo? y Afrusino?) en Ontinyent (1 fot.) -- [25]. El niño Francisco Roglá López con sombrero a la derecha de la imagen y Facundo Roglá Alarte el tercero por la derecha del grupo de sacerdotes (entre ellos José del Campo? y Afrusino?) en Ontinyent (1 fot.) -- [26]. Desfile de grupo de personas acompañando a un sacerdote, muchos de ellos con paraguas (1 fot.) -- [27]. José Roglá López con amigos o familiares modelando barro en la alfarería y fábrica de tejas y ladrillos los Torneros de Ayora (1 fot.) -- [28]. Alfarera pintando una vasija de cerámica en la fábrica los Torneros (1 par estereoscópico) (1 fot.)

Fabular edificando. La obra de Cortina

Este libro contiene la investigación llevada a cabo bajo la dirección de Joaquín Arnau Amo y la coordinación de Inmaculada Narbona Calvo sobre la obra del arquitecto José María Manuel Cortina (1868-1950). El equipo de investigadores está formado por Joaquín Arnau Amo, Javier Poyatos Sebastián, María Elia Gutiérrez Mozo, José Luis Baró Zarzo y Joaquín Arnau Navarro. Los adjuntos al equipo son Jorge Girbés Pérez, María Elisa Moliner Cantos y Tomás Roselló Jaunzarás. La investigación dio lugar a una exposición en el Centro del Carmen de Valencia cuyo catálogo asimismo se recoge, precedido de las aportaciones de los citados investigadores, a las cuales se sumaron las de Miguel Ángel Baldellou Santolaria, Joan Bassegoda Nonell, Jaume Coll Conesa, Carmen Rodríguez Pedret y Francisco Taberner Pastor.

Análisis de la próxima modernización del pilar comercial del Acuerdo global entre la Unión Europea y México

El Acuerdo global firmado en 1997 entre la Comunidad Europea y sus Estados miembros y México, junto con el conjunto de decisiones adoptadas en este marco, ha sido eficaz y, por tanto, las modificaciones de este acuerdo se ven motivadas principalmente por el cambio del panorama mundial desde que este se promulgó por primera vez. Por ello, para las próximas negociaciones con México, es sumamente importante prestar atención a las consideraciones generales sobre cómo se configura la política comercial de la Unión Europea. En este contexto, se analizan las necesidades y expectativas, tanto de la UE como de México, con respecto a cualquier futuro acuerdo, haciendo especial hincapié en ámbitos que van más allá del comercio de bienes y servicios, tales como la contratación pública, la inversión y la cooperación regulatoria. Se defiende que, para cualquier modificación, deben tomarse como modelo los «antiguos» acuerdos de asociación, teniendo en cuenta que se centran en temas específicos de la UE y su capacidad para atender a las necesidades de México en cualquier acuerdo más avanzado que se vaya a celebrar.

Flaquezas y desengaños : comedia en tres actos, y en verso /

"Representada por primera vez en el Teatro de Variedades el 7 de febrero de 1849, á beneficio de la actriz doña María Muñoz".

Balanza métrica, ó sea Igualdad de las pesas y medidas legales de Castilla, las de las cuarenta y nueve provincias de España, sus posesiones de Ultramar, isla de Cuba, Puerto-Rico y Filipinas, y las de Francia, Inglaterra y Portugal : todas con el sistema métrico y viceversa ... /

Mode of access: Internet.

Relationship between sunlight and the age of onset of bipolar disorder:an international multisite study

Background - The onset of bipolar disorder is influenced by the interaction of genetic and environmental factors. We previously found that a large increase in sunlight in springtime was associated with a lower age of onset. This study extends this analysis with more collection sites at diverse locations, and includes family history and polarity of first episode. Methods - Data from 4037 patients with bipolar I disorder were collected at 36 collection sites in 23 countries at latitudes spanning 3.2 north (N) to 63.4 N and 38.2 south (S) of the equator. The age of onset of the first episode, onset location, family history of mood disorders, and polarity of first episode were obtained retrospectively, from patient records and/or direct interview. Solar insolation data were obtained for the onset locations. Results - There was a large, significant inverse relationship between maximum monthly increase in solar insolation and age of onset, controlling for the country median age and the birth cohort. The effect was reduced by half if there was no family history. The maximum monthly increase in solar insolation occurred in springtime. The effect was one-third smaller for initial episodes of mania than depression. The largest maximum monthly increase in solar insolation occurred in northern latitudes such as Oslo, Norway, and warm and dry areas such as Los Angeles, California. Limitations - Recall bias for onset and family history data. Conclusions - A large springtime increase in sunlight may have an important influence on the onset of bipolar disorder, especially in those with a family history of mood disorders.

Influence of birth cohort on age of onset cluster analysis in bipolar I disorder

PURPOSE: Two common approaches to identify subgroups of patients with bipolar disorder are clustering methodology (mixture analysis) based on the age of onset, and a birth cohort analysis. This study investigates if a birth cohort effect will influence the results of clustering on the age of onset, using a large, international database. METHODS: The database includes 4037 patients with a diagnosis of bipolar I disorder, previously collected at 36 collection sites in 23 countries. Generalized estimating equations (GEE) were used to adjust the data for country median age, and in some models, birth cohort. Model-based clustering (mixture analysis) was then performed on the age of onset data using the residuals. Clinical variables in subgroups were compared. RESULTS: There was a strong birth cohort effect. Without adjusting for the birth cohort, three subgroups were found by clustering. After adjusting for the birth cohort or when considering only those born after 1959, two subgroups were found. With results of either two or three subgroups, the youngest subgroup was more likely to have a family history of mood disorders and a first episode with depressed polarity. However, without adjusting for birth cohort (three subgroups), family history and polarity of the first episode could not be distinguished between the middle and oldest subgroups. CONCLUSION: These results using international data confirm prior findings using single country data, that there are subgroups of bipolar I disorder based on the age of onset, and that there is a birth cohort effect. Including the birth cohort adjustment altered the number and characteristics of subgroups detected when clustering by age of onset. Further investigation is needed to determine if combining both approaches will identify subgroups that are more useful for research.

Influence of light exposure during early life on the age of onset of bipolar disorder

Background: Environmental conditions early in life may imprint the circadian system and influence response to environmental signals later in life. We previously determined that a large springtime increase in solar insolation at the onset location was associated with a younger age of onset of bipolar disorder, especially with a family history of mood disorders. This study investigated whether the hours of daylight at the birth location affected this association. Methods: Data collected previously at 36 collection sites from 23 countries were available for 3896 patients with bipolar I disorder, born between latitudes of 1.4N and 70.7N, and 1.2S and 41.3S. Hours of daylight variables for the birth location were added to a base model to assess the relation between the age of onset and solar insolation. Results: More hours of daylight at the birth location during early life was associated with an older age of onset, suggesting reduced vulnerability to the future circadian challenge of the springtime increase in solar insolation at the onset location. Addition of the minimum of the average monthly hours of daylight during the first 3 months of life improved the base model, with a significant positive relationship to age of onset. Coefficients for all other variables remained stable, significant and consistent with the base model. Conclusions: Light exposure during early life may have important consequences for those who are susceptible to bipolar disorder, especially at latitudes with little natural light in winter. This study indirectly supports the concept that early life exposure to light may affect the long term adaptability to respond to a circadian challenge later in life.

Unveiling temporal correlations characteristic of a phase transition in the output intensity of a fiber laser

We use advanced statistical tools of time-series analysis to characterize the dynamical complexity of the transition to optical wave turbulence in a fiber laser. Ordinal analysis and the horizontal visibility graph applied to the experimentally measured laser output intensity reveal the presence of temporal correlations during the transition from the laminar to the turbulent lasing regimes. Both methods unveil coherent structures with well-defined time scales and strong correlations both, in the timing of the laser pulses and in their peak intensities. Our approach is generic and may be used in other complex systems that undergo similar transitions involving the generation of extreme fluctuations.

Efectos de la ketamina o la alfaxalona y su combinación con diazepam o dexmedetomidina en el cerdo

La especie porcina constituye hoy en día la de elección en muchos modelos experimentales utilizados en investigación, debido principalmente, a sus similitudes anatómicas y fisiológicas y a su reactividad farmacológica con el hombre; sin embargo son animales de difícil manejo que se estresan con facilidad, por lo que la vía intramuscular constituye la vía más cómoda y fácil de utilizar. Tradicionalmente se ha utilizado, para la tranquilización y anestesia de la especie porcina la ketamina, combinada con benzodiacepinas o con agonistas de los receptores adrenérgicos α2 habituales; sin embargo, recientemente se están empleando nuevos y potentes fármacos para la tranquilización y anestesia de esta especie, entre los que se encuentran la dexmedetomidina, un agonista potente, eficaz y selectivo de los receptores adrenérgicos α2 sobre el sistema nervioso central y periférico. La bradicardia e hipotensión se encuentran entre sus efectos adversos más comunes, sin embargo ejerce un efecto leve sobre la ventilación y produce un excelente efecto sedante y antinociceptivo, disminuyendo los requerimientos de otros fármacos anestésicos intravenosos, con la ventaja de poder ser antagonizada, por lo que viene siendo utilizada en medicina veterinaria tanto en el campo de la anestesiología clínica como en la captura y manejo de animales exóticos. La dexmedetomidina se ha empleado tanto en medicina humana como en veterinaria de forma parenteral sola y/o combinada con ketamina o alfaxalona...

Early growth characteristics and the risk of reduced lung function and asthma : a meta-analysis of 25,000 children

Peer reviewed

Early growth characteristics and the risk of reduced lung function and asthma : a meta-analysis of 25,000 children

Peer reviewed

Investigating optical complexity of the phase transition in the intensity of a fibre laser radiation

Fibre lasers have been shown to manifest a laminar-to-turbulent transition when increasing its pump power. In order to study the dynamical complexity of this transition we use advanced statistical tools of time-series analysis. We apply ordinal analysis and the horizontal visibility graph to the experimentally measured laser output intensity. This reveal the presence of temporal correlations during the transition from the laminar to the turbulent lasing regimes. Both methods allow us to unveil coherent structures with well defined time-scales and strong correlations both, in the timing of the laser pulses and in their peak intensities.

EDUCATING THE PUBLIC THROUGH NEWS MEDIA: CASE STUDIES OF NEWS LITERACY IN THE NEW MEDIA LANDSCAPE

Two decades of unprecedented changes in the media landscape have increased the complexity of informing the public through news media. With significant changes to the way the news industry does business and the way news consumers access this information, a new set of skills is being proposed as essential for today’s news consumer. News literacy is the use of critical thinking skills to assess the reliability and source of the information that people consume on a daily basis, as well as fostering self-awareness of personal news consumption habits and how it can create audience bias. The purpose of this study was to examine how adults experience the news in their everyday lives and to describe the nature of the news literacy skills people employ in their daily news consumption. This study purposefully selected four adults who have completed high school, and who regularly consume news information across a number of platforms, both traditional and digital. Two of the participants, one man and one woman, were over 50 years old. One other male participant was in his 30’s and the final participant, a young woman, was in her 20’s. They all utilized both traditional and digital media on a regular basis and all had differing skill levels when using social media for information. Their news experiences were documented by in-depth interviews and the completion of seven daily news logs. In their daily logs the participants differentiated news information from other information available on-line but the interviews revealed a contradiction between their intentions and their news consumption practices. All four participants had trouble distinguishing between news and opinion pieces in the news information realm. In addition all but one seemed unaware of their personal bias and any possible effect it was having on their news consumption. Further research should explore the benefits of an adult-centered news literacy curriculum on news consumers similar to the participants, and should examine the development of audience bias and its relationship to the daily exposure people have to the torrent of information that is available to them on a daily basis.