727 resultados para RIVADAVIA, BERNARDINO
Resumo:
Innate immunity is based in pre-existing elements of the immune system that directly interact with all types of microbes leading to their destruction or growth inhibition. Several elements of this early defense mechanism act in concert to control initial pathogen growth and have profound effect on the adaptative immune response that further develops. Although most studies in paracoccidioidomycosis have been dedicated to understand cellular and humoral immune responses, innate immunity remains poorly defined. Hence, the main purpose of this review is to present and discuss some mechanisms of innate immunity developed by resistant and susceptible mice to Paracoccidioides brasiliensis infection, trying to understand how this initial host-pathogen interface interferes with the protective or deleterious adaptative immune response that will dictate disease outcome. An analysis of some mechanisms and mediators of innate immunity such as the activation of complement proteins, the microbicidal activity of natural killer cells and phagocytes, the production of inflammatory eicosanoids, cytokines, and chemokines among others, is presented trying to show the important role played by innate immunity in the host response to P. brasiliensis infection.
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We study the collider phenomenology of bilinear R-parity violating supergravity, the simplest effective model for supersymmetric neutrino masses accounting for the current neutrino oscillation data. At the CERN Large Hadron Collider the center-of-mass energy will be high enough to probe directly these models through the search for the superpartners of the Standard Model (SM) particles. We analyze the impact of R-parity violation on the canonical supersymmetry searches-that is, we examine how the decay of the lightest supersymmetric particle (LSP) via bilinear R-parity violating interactions degrades the average expected missing momentum of the reactions and show how this diminishes the reach in the usual channels for supersymmetry searches. However, the R-parity violating interactions lead to an enhancement of the final states containing isolated same-sign di-leptons and trileptons, compensating the reach loss in the fully inclusive channel. We show how the searches for displaced vertices associated to LSP decay substantially increase the coverage in supergravity parameter space, giving the corresponding reaches for two reference luminosities of 10 and 100 fb(-1) and compare with those of the R-parity conserving minimal supergravity model.
Resumo:
A presente dissertação investiga questão dos conflitos no relacionamento entre franqueadores franqueados. apresentado um referencial teórico onde franchising se insere no contexto dos canais de marketing, bem como as causas mais freqüentes de surgimento de conflitos entre franqueadores franqueados e as formas de solução existentes. Em seguida, são apresentados os resultados de uma pesquisa exploratória, baseada no Estudo de Casos, realizada junto a uma rede de franquias atuante no ramo varejista, onde se procura destacar os conflitos observados no contexto da relação franqueador franqueado evidenciar como seus integrantes os previnem os administram. Por fim, recomendações são apresentadas.
Resumo:
Trata do gerenciamento da carteira de inadimplentes no mercado de crédito ao consumidor, em especial no de cartões de crédito. Foca a concepção, desenvolvimento e manutenção do modelo de collection scoring como ferramenta para a administração da carteira de inadimplentes, considerada fundamental na gestão estratégica e profissional do risco de crédito ao consumidor. Caracteriza o problema da inadimplência, tanto no mercado de crédito ao consumidor como no de cartões de crédito, e aponta tendências e alternativas para o seu gerenciamento estratégico
Resumo:
O trabalho utiliza conceitos da economia do bem estar e a elasticidade da renda tributável para analisar o custo social das reações comportamentais dos contribuintes do imposto de renda sobre as pessoas físicas no Brasil, em resposta a uma mudança de política tributária. A elasticidade da renda tributável despertou grande atenção recente, motivada pela perspectiva de estimar em conjunto todas as reações comportamentais a uma mudança no sistema tributário através de um único parâmetro, mensurando custos de eficiência e de bem estar suportados pela economia de forma relativamente simples. O trabalho aborda a utilização de medidas de variação de bem estar para avaliar mudanças na política tributária e faz uma resenha da literatura sobre a elasticidade da renda tributável, conceitos, características, vantagens e limitações. Um modelo de preferências é especificado para exemplificar a dimensão das reações à tributação e os custos de eficiência envolvidos, e discutir a viabilidade do emprego da elasticidade da renda tributável como parâmetro estrutural.
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Este trabalho visa analisar o processo de implementação de políticas voltadas à garantia dos direitos humanos na cidade de São Paulo, enfocando as ações voltadas à qualificação profissional da população em situação de rua através do PRONATEC – Programa Nacional de Acesso ao Ensino Técnico e Emprego –, com vistas a inserir essa população vulnerável socioeconomicamente no mercado de trabalho. Para traçar essas análises, buscar-se-á explorar a implementação do chamado “PRONATEC PopRua” sob a perspectiva dos arranjos político-institucionais que conformam o arcabouço jurídico-legal, técnico-administrativo e político que envolvem o processo de execução, bem como compreender sob qual quadrante da matriz político-operativa se situa a política, denotando o caráter dinâmico-intervencionista dessa política pública.
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Esta dissertação foi desenvolvida visando problematizar a gestão da transversalidade nas políticas de direitos humanos e de participação social no Município de São Paulo, considerando as propostas e práticas da recém-criada Secretaria Municipal de Direitos Humanos e Cidadania (SMDHC). A partir do método de estudo de caso desenvolvido por Robert Yin (2001), buscou-se compreender a estrutura da Secretaria, os mecanismos pelos quais desenvolve seu papel articulador e elaborador de políticas públicas e os principais desafios da sua gestão transversal. Partindo de um referencial teórico sobre o conceito de transversalidade e intersetorialidade e a relação destas com as políticas públicas de direitos humanos e de participação social, foram estabelecidas seis varáveis de análise que orientaram a construção deste trabalho – gestão estratégica, participação social, gestão de informação, gestão administrativa e de pessoas, capacidade política e institucional e relações federativas.. Os autores concluiram que a radicalização da transversalidade como modelo de gestão favorece a universalização da garantia dos direitos humanos na cidade de São Paulo. Ao final foram formuladas propostas que visam contribuir para a gestão transversal das políticas públicas, sob a perspectiva de garantia e defesa de direitos e participação social e fortalecimento do papel articulador da Secretaria no conjunto da Prefeitura.
Resumo:
This thesis reports on research done for the integration of eye tracking technology into virtual reality environments, with the goal of using it in rehabilitation of patients who suffered from stroke. For the last few years, eye tracking has been a focus on medical research, used as an assistive tool to help people with disabilities interact with new technologies and as an assessment tool to track the eye gaze during computer interactions. However, tracking more complex gaze behaviors and relating them to motor deficits in people with disabilities is an area that has not been fully explored, therefore it became the focal point of this research. During the research, two exploratory studies were performed in which eye tracking technology was integrated in the context of a newly created virtual reality task to assess the impact of stroke. Using an eye tracking device and a custom virtual task, the system developed is able to monitor the eye gaze pattern changes over time in patients with stroke, as well as allowing their eye gaze to function as an input for the task. Based on neuroscientific hypotheses of upper limb motor control, the studies aimed at verifying the differences in gaze patterns during the observation and execution of the virtual goal-oriented task in stroke patients (N=10), and also to assess normal gaze behavior in healthy participants (N=20). Results were found consistent and supported the hypotheses formulated, showing that eye gaze could be used as a valid assessment tool on these patients. However, the findings of this first exploratory approach are limited in order to fully understand the effect of stroke on eye gaze behavior. Therefore, a novel model-driven paradigm is proposed to further understand the relation between the neuronal mechanisms underlying goal-oriented actions and eye gaze behavior.
Resumo:
The pulsed plasma nitriding is a solution currently used in the metallurgical industry to resolve problems earlier in the processing of parts by using plasma DC voltage. These problems consisted mainly of edge effect and opening arches caused due to non-uniformity of electric fields on uneven surfaces. By varying the pulse width can reduce these effects. However, variations in pulse width can drastically affect the population of the plasma species and hence the final microstructure of the nitrided layer. In literature, little is known about the effect of process parameters on the properties of the plasma species and, consequently, the surface properties. We have developed a system of nitriding with pulsed source with fixed period of 800 pulse width is variable. Examined the variation of these parameters on the properties of nitrided surface when keeping constant temperature, gas composition, flow, pressure and power. It was found that the values of width and pulse repetition time of considerable influence in the intensities of the species present in plasma. Moreover, we observed the existence of the edge effect for some values of pulse widths, as well as changes in surface roughness and hardness
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Este trabalho foi realizado para avaliar o desenvolvimento e reprodução de Tetranychus urticae em cultivares comerciais de mamão Carica papaya. Foram utilizadas cultivares do grupo Formosa (Tainung 01 e Calimosa) e do grupo Solo (Golden e Sunrise). Para iniciar o bioensaio, foi transferida uma fêmea fertilizada por disco de folha (n=50 repetições) e retirado após um período de 12h, sendo avaliada a cada 12h, registrando-se o período de incubação, duração do estágio de imaturo, longevidade e fecundidade dos adultos e viabilidade desses estágios. Os resultados indicaram que as cultivares de mamão Tainung 01, Calimosa, Sunrise e Golden são bons hospedeiros para T. urticae. O parâmetro viabilidade não sofreu influência das cultivares em todas as fases de desenvolvimento avaliadas, apresentando valores superiores a 90%. Não houve diferença estatística entre as cultivares nos parâmetros: período de pre-oviposição e viabilidade dos ovos. A cultivar Tainung 01 apresentou menor potencial hospedeiro, embora houvesse menor duração nos estágios de ovo, larva, protoninfa e ovo-adulto. Nos parâmetros de tabela de vida e fertilidade, apresentou menores valores de Ro, r m e λ e maior valor de Td. Entre as cultivares, o Sunrise apresentou um elevado potencial hospedeiro para T. urticae, pois essa cultivar proporcionou a maior produção de ovos por fêmea, maior longevidade das fêmeas, bem como a maior taxa de reprodução (maior Ro, r m e λ e menor valor de Td).
Resumo:
A finite-difference scheme is used to calculate bound electronic states of an electron in a hydrogen atom subject to a magnetic field. The numerical results are in good agreement with exact results, in the absence of the magnetic field, and with a two-parameters variational calculation, when the magnetic field is applied.
Resumo:
This research stands in discussions involving the relationship between memory, history and space. We will work with the Café São Luiz in the neighborhood of Cidade Alta in Natal, an place which remains open and founded in 1953. The place was opened in the district of greater movement of the 1950s, a zone of concentration of commerce and leisure. In consequence an impulse of memory, the Café São Luiz was represented by different statements, which they built a space that serves to support memory and identity of a group. The speeches elaborate the Café São Luiz as a monument, a place of memory according to Pierre Nora. Among these discourses of construction of the Café São Luiz stands out the 1982 book titled Na Calçada do Café São Luiz by José Luiz Silva. This research aims to discuss the construction of the Café São Luiz as a place of memory, questioning their representations, traversing the authorship of speeches over the place
Resumo:
This work presents a proposal for introducing the teaching of Geometry Space study attempts to demonstrate that the use of manipulatives as a teaching resource can be an alternative learning facilitator for fixing the primitive concepts of geometry, the postulates and theorems, position relationships between points, lines and planes and calculating distances. The development makes use of a sequence of activities aimed at ensuring that students can build a more systematic learning and these are divided into four steps
Resumo:
Generally, arithmetic and geometric progressions are taught separately from ane and exponential functions, only by the use of memorized formulas and without any concern of showing students how these contents are related. This paper aims at presenting a way of teaching such contents in an integrated way, starting with the definition of ane and exponential functions relating them to situations from the daily life of the students. Then, characteristics and graphics of those functions are presented and, subsequently, arithmetic and geometric progression are shown as a restriction of the ane and exponential functions. Thus, the study of the progressions is introduced based on the functions mentioned above using situations from students daily lives as examples
Resumo:
In this study, we sought to address the weaknesses faced by most students when they were studying trigonometric functions sine and cosine. For this, we proposed the use of software Geogebra in performing a sequence of activities about the content covered. The research was a qualitative approach based on observations of the activities performed by the students of 2nd year of high school IFRN - Campus Caicfio. The activities enabled check some diculties encountered by students, well as the interaction between them during the tasks. The results were satisfactory, since they indicate that the use of software contributed to a better understanding of these mathematical concepts studied