Investment and economic reform in Latin America

Includes bibliography

América Latina y el Caribe: la propiedad intelectual después de los tratados de libre comercio

Incluye Bibliografía

The contribution of biofuels to the sustainability of development in Latin America and the Caribbean

Includes bibliography

TORP: An open standard framework for humanoid robots

Humanoid robots are an extremely complex interdisciplinary research field. Particularly, the development of high size humanoid robots usually requires joint efforts and skills from groups that are in many different research centers around the world. However, there are serious constraints in this kind of collaborative development. Some efforts have been made in order to propose new software frameworks that can allow distributed development with also some degree of hardware abstraction, allowing software reuse in successive projects. However, computation represents only one of the dimensions in robotics tasks, and the need for reuse and exchange of full robot modules between groups are growing. Large advances could be reached if physical parts of a robot could be reused in a different robot constructed with other technologies by other researcher or group. This paper proposes a new robot framework, from now on called TORP (The Open Robot Project), that aims to provide a standard architecture in all dimensions (electrical, mechanical and computational) for this collaborative development. This methodology also represents an open project that is fully shared. In this paper, the first robot constructed following the TORP specification set is presented as well as the advances proposed for its improvement. © 2010 IEEE.

Synthesis and evaluation of diethylethylamine-chitosan for gene delivery: Composition effects on the in vitro transfection efficiency

Chitosan has been indicated as a safe and promising polycation vector for gene delivery. However its low transfection efficiency has been a challenging obstacle for its application. To address this limitation, we synthesized chitosan derivatives which had increasing amounts of diethylethylamine groups (DEAE) attached to the chitosan main chain. The plasmid DNA VR1412 (pDNA), encoding the ß-galactosidase (ß-gal) reporter gene was used to prepare nanoparticles with the chitosan derivatives, and the transfection studies were performed with HeLa cells. By means of dynamic light scattering and zeta potential measurements, it was shown that diethylethylamine-chitosan derivatives (DEAEx-CH) were able to condense DNA into small particles having a surface charge depending on the polymer/DNA ratio (N/P ratio). Nanoparticles prepared with derivatives containing 15 and 25% of DEAE groups (DEAE15-CH and DEAE25-CH) exhibited transfection efficiencies ten times higher than that observed with deacetylated chitosan (CH). For derivatives with higher degrees of substitution (DS), transfection efficiency decreased. The most effective carriers showed low cytotoxicity and good transfection activities at low charge ratios (N/P). Vectors with low DS were easily degraded in the presence of lysozyme at physiological conditions in vitro and the nontoxicity displayed by these vectors opens up new opportunities in the design of DEAE-chitosan-based nanoparticles for gene delivery. © 2013 IOP Publishing Ltd.

In Situ Formation of Dendrites in Eumelanin Thin Films between Gold Electrodes

Eumelanin is a ubiquitous pigment in the human body, animals, and plants, with potential for bioelectronic applications because of its unique set of physical and chemical properties, including strong UV-vis absorption, mixed ionic/electronic conduction, free radical scavenging and anti-oxidant properties. Herein, a detailed investigation is reported of eumelanin thin films grown on substrates patterned with gold electrodes as a model system for device integration, using electrical measurements, atomic force microscopy, scanning electron microscopy, fluorescence microscopy, and time-of-flight secondary ion mass spectroscopy. Under prolonged electrical biasing in humid air, one can observe gold dissolution and formation of gold-eumelanin nanoaggregates, the assembly of which leads to the formation of dendrites forming conductive pathways between the electrodes. Based on results collected with eumelanins from different sources, a mechanism is proposed for the formation of the nanoaggregates and dendrites, taking into account the metal binding properties of eumelanin. The surprising interaction between eumelanin and gold points to new opportunities for the fabrication of eumelanin-gold nanostructures and biocompatible memory devices and should be taken into account in the design of devices based on eumelanin thin films. © 2013 WILEY-VCH Verlag GmbH & Co.

In vitro targeting of Polo-like kinase 1 in bladder carcinoma: Comparative effects of four potent inhibitors

Despite the improvements in neoadjuvant chemotherapy, the outcome of patients with advanced bladder cancer has changed very little over the past 30 years. In the present study we tested and compared the in vitro antitumor activities of four different inhibitors of Polo-like kinase 1 (PLK1) (BI 2536, BI 6727, GW843682X, and GSK461364), against 3 bladder carcinoma cell lines RT4, 5637 and T24. The impact on radiosensitivity and drug interactions in simultaneous treatments with cisplatin, methotrexate, and doxorubicin were also investigated. Our results showed that PLK1 inhibition prevented cell proliferation and clonogenicity, causing significant inhibition of invasion of tumor cells, though modest differences were observed between drugs. Moreover, all PLK1 inhibitors induced G2/M arrest, with the subsequent induction of death in all 3 cell lines. Drug interactions studies showed auspicious results for all PLK1 inhibitors when combined with the commonly used cisplatin and methotrexate, though combinations with doxorubicin showed mostly antagonistic effects. Comparably, the four PLK1 inhibitors efficiently sensitized cells to ionizing radiation. Our findings demonstrate that irrespective of the inhibitor used, the pharmacological inhibition of PLK1 constrains bladder cancer growth and dissemination, providing new opportunities for future therapeutic intervention. However, further laboratorial and preclinical tests are still needed to corroborate the usefulness of using them in combination with other commonly used chemotherapeutic drugs. © 2013 Landes Bioscience.

The digital economy for structural change and equality

Includes bibliography.

ECLAC Notes Nº 7

Brazil gradually overcomes trauma of inflation Transparency and military spending in Latin America Opinion: Employment and the crisis Highlights: Women now work moreIndicators Maritime profile of Latin America and the Caribbean on ECLAC's website Recent titles Calendar

ECLAC Notes Nº 58

Special edition dedicated to the Thirty-second session of ECLAC (Santo Domingo, Dominican Republic,9-13 June 2008): Structural Change and Productivity Growth, 20 Years Later. Old problems, new opportunities ECLAC Presents Report on Financing for Development Op-ed by ECLAC's Executive Secretary, José Luis Machinea. New Opportunities for Latin America and the Caribbean Highlights. Public-private Alliances for Export DevelopmentIndicatorsOp-ed by ECLAC's Executive Secretary, José Luis Machinea. Latin America and theCaribbean in the New International Context Recent titles Calendar of events

Regional Climate Modelling In The Caribbean

The information here represents a compilation of existing and ongoing regional and national climate modelling studies that could be useful in the execution of the regional project The Economics of Climate Change in Caribbean. The report is mainly focused on the sustainable regional efforts that represent opportunities for further developments in climate change scenarios. It describes the different techniques that have been used to model changes in temperature and precipitation in the Caribbean and compares the outputs of these models. Essentially, temperatures are expected to increase while precipitation may increase for countries in the more southerly latitudes, but decrease for more northerly countries (Bahamas, Cuba and Hispaniola) resulting in drought. These changes would present tremendous challenges for the Caribbean subregion and, despite significant progress made in recent years, there is a need for continuous development of climate research and modelling in the subregion, to produce more relevant information for regional and national studies and to overcome the limitations of existing results. This may well be realized through coordination of activities between the Caribbean Community Climate Change Centre (CCCCC), the Institute of Meteorology (INSMET) in Cuba and the University of the West Indies (UWI). These activities will address the implementation of further analyses using available information to generate best practices and to produce useful results. There are also new opportunities for climate research in the region with Coordinated Regional Downscaling Experiment (CORDEX) which is planned to start early next year. It is expected that the participation of various Caribbean institutions like INSMET, UWI, CCCC and the Caribbean Institute for Meteorology and Hydrology in this global project will allow the generation of new and more abundant information.

O profissional de serviço social na educação infantil

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Melhoramento participativo de abóbora (Cucurbita moschata Dusch), sob manejo biodinâmico

Pós-graduação em Agronomia (Horticultura) - FCA

Revendo o gênero: a representação da mulher no Bildungsroman feminino contemporâneo

Pós-graduação em Letras - IBILCE

Media Education and Brazilian Educational Policies for the Enhancement of Learning

As media education concepts and practices have been disseminated and strengthened in European countries and Americas, the policies responsible for that expansion remain little known, particularly in countries where the achievements have been recently noted. That is the case for Brazil, where there have been new opportunities for media education, considered as a valuable resource to help accomplish goals of the educational system. This paper looks into the contribution of media education to the enhancement of teaching and learning in the context of innovations brought by recent policies of the Brazilian Ministry of Education. After educational reform programmes which brought the opportunity for emerging fields such as media education, we produced teaching material and conducted a series of workshops with students and teachers from state secondary schools. By reading and producing multimedia information about local public services available to young people, pupils learned about democracy, citizenship, civic engagement, media language, and identity. Lessons from our experiment are discussed against the backdrop of education policies being implemented to ameliorate harsh conditions resulting from the recent economic crisis. We suggest that media education can help by creating a learning environment in which the students become aware of the value of educational attainments.