358 resultados para Miki Kiyoshi
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Bibliography: p. 24.
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Bibliography: p. 72-74.
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Mode of access: Internet.
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Mode of access: Internet.
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Mode of access: Internet.
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O kuma Shigenobu no sho zo ari.
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Mode of access: Internet.
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Cover-title.
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Vol. 3-4 published by Hitata Gakkai; v.5-15, by Hōbunkan Shoten.
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Front Row (Left to Right): William Farah, Brook Blain, David Paradzik, Arvid Swran, Miki Pusztai, Jake Kaiton
Second Row: head Coach Brian Eisner, Tomas Filipcik, Matt Wright, John Long, Brad McFarlane, student trainer Andy Galbreath, assistant coach Dan Goldberg.
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Front Row: David Paradzik, Miki Pusztai, Arvid Swan, Brook Plain
Back Row: assistant coach Da Goldberg, William Farah, Jake Raiton, John Long, Matt Wright, Brad MacFarlane, head coach Brian Eisner
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Top Row: Michelle Arsulowicz, Christy L. baginski, Sarah Ball, Jessica Beitner, Gina Blank, Kelley Brown, Cheryl Buckler, Loredana Bugan, Kelly Burrows, Cynthia Carillo, Raquel Casarez, Rachel Cieslak, Nicole Clark, Stephanie Cochran, John condon
Row 2: Becky Cooper, Claire Coughlan, Heidi M. Dillenbeck, Jennfier Long, Tracy Adame, Stacy B. Buchanan, Tiffany A. Fellberg, Elise H. Peterson, Jessica Na, Abigail Sikkenga, Michelle, Falatko, Lisa Dolan, Laura Dorman, Suzanne Ewald
Row 3: Heather Fix, Anna galczyk, Inessa Gankin, Elizabeth Gardner, Jennfier Gray, Katy Gudritz, Lindsey Hancock, Christina Haremski, Marcie Harless, Anne Hartgerink
Row 4: Benjamin Hatchett, Karrie Herdus, Lacy Hillman, Amy Hlavka, Nicole Holt, Julie Huss, Jessica Inwood, Sujuan Johnson, Nicole N. Jones, Jennfier M. kenny
Row 5: Lori Khami, Jennifer Kiebler, Nipa Kinariwala, Kelli Kingma, Elizabeth Kubis, Jillian LaPrairie, Heather Livermore, Emily Long-Minard, Miki Loveland, Meyhan Manion, David Markiewicz, Dareth McCoy
Row 6: Kerri McElmeel, Suzanne McQuaid, Katie Murphy, Marie Murray, Nola Pender, Carol Loveland-Cherry, Ada Sue Hinshaw, Susan Boehm, Beverly Jones, Patricia coleman-Burns, Darlene Najor, Kelly Nowak, Charisse Patterson, Jennfier Pliska
Row 7: Heather Prusi, Erika Punches, Gena ramazetti, Kimberly Rendz, Suzanne Robben, Sara Robbins, Lori rottschafer, Annette Sandretto, Sara Schad, Chad Schenavar, Jennifer Seamon, Katherine Shell, Charlotte L. Sims, Caryn Steenland, Andrea Stutzman
Row 8: Jennifer Thibault, stacey Turnipseed, Linda Twomey, Stephanie Van Eyk, Maryanne VanNasdale, Annemarie Vassalo, Anna Walawender, Mark Warren, Nicole Weber, Kindra Weid, Lela Shitley, Kristy Wierzba, Shari Wilkinson, Lily Wu
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Mode of access: Internet.
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The number of known mRNA transcripts in the mouse has been greatly expanded by the RIKEN Mouse Gene Encyclopedia project. Validation of their reproducible expression in a tissue is an important contribution to the study of functional genomics. In this report, we determine the expression profile of 57,931 clones on 20 mouse tissues using cDNA microarrays. Of these 57,931 clones, 22,928 clones correspond to the FANTOM2 clone set. The set represents 20,234 transcriptional units (TUs) out of 33,409 TUs in the FANTOM2 set. We identified 7206 separate clones that satisfied stringent criteria for tissue-specific expression. Gene Ontology terms were assigned for these 7206 clones, and the proportion of 'molecular function' ontology for each tissue-specific clone was examined. These data will provide insights into the function of each tissue. Tissue-specific gene expression profiles obtained using our cDNA microarrays were also compared with the data extracted from the GNF Expression Atlas based on Affymetrix microarrays. One major outcome of the RIKEN transcriptome analysis is the identification of numerous nonprotein-coding mRNAs. The expression profile was also used to obtain evidence of expression for putative noncoding RNAs. In addition, 1926 clones (70%) of 2768 clones that were categorized as unknown EST, and 1969 (58%) clones of 3388 clones that were categorized as unclassifiable were also shown to be reproducibly expressed.
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Classical cadherin adhesion molecules are fundamental determinants of cell-cell recognition that function in cooperation with the actin cytoskeleton. Productive cadherin-based cell recognition is characterized by a distinct morphological process of contact zone extension, where limited initial points of adhesion are progressively expanded into broad zones of contact. We recently demonstrated that E-cadherin ligation recruits the Arp2/3 actin nucleator complex to the plasma membrane in regions where cell contacts are undergoing protrusion and extension. This suggested that Arp2/3 might generate the protrusive forces necessary for cell surfaces to extend upon one another during contact assembly. We tested this hypothesis in mammalian cells by exogenously expressing the CA region of N-WASP. This fragment, which potently inhibits Arp2/3-mediated actin assembly in vitro, also effectively reduced actin assembly at cadherin adhesive contacts. Blocking Arp2/3 activity by this strategy profoundly reduced the ability of cells to extend cadherin adhesive contacts but did not affect cell adhesiveness. These findings demonstrate that Arp2/3 activity is necessary for cells to efficiently extend and assemble cadherin-based adhesive contacts.