Measuring and predicting non-functional properties of customizable programs

Magdeburg, Univ., Fak. für Informatik, Diss., 2012

apoptosis-regulator c-FLIP : functional role in urothelial carcinoma and autoimmunity and identification of novel CD95 DISC-interacting proteins

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2013

Long memory model of resting state functional MRI

Magdeburg, Univ., Fak. für Elektrotechnik und Informationstechnik, Diss., 2013

Generation of functional macrophages from adult mesenchymal stem cells

Magdeburg, Univ., Med. Fak., Diss., 2013

Functional studies on the role of I[Kappa]B NS in T helper cell differentiation

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2014

Functional studies of β-arresting and αB-crystallin as interaction partners of PAR-1 and PAR-2 and their involvement in protective and proliferative signaling pathways in astrocytes

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2014

Analysis of functional impairments of the human P2Y 11 nucleotide receptor with the alanine-87 - threonine mutation, and development of novel agonists specific for the human P2Y 11 and P2Y 6 receptors

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2015

Ultra-high resolution imaging of the functional anatomy and plasticity of the human hippocampal-entorhinal circuitry

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2015

Functional design of the air ventilation apparatus and overland excurions by teleosts / Karel F. Liem.

n.s. no.37(1987)

Comparative functional anatomy of the Nandidae (Pisces: Teleostei) [by] Karel F. Liem.

v.56(1970)

Revised phylogeny and functional interpretation of the Edrioasteroidea based on new taxa from the Early and Middle Ordovician of western Utah / Thomas E. Guensburg --, James Sprinkle --.

n.s. no.29(1994)

Morphological and functional study of the marginal sphincter of the sea anemones Phymactis clematis and Aulactinia marplatensis from intertidal of Mar del Plata, Argentina

It was made the characterization of marginal sphincter to the species Phymactis clematis (Drayton in Dana, 1849) and Aulactinia marplatensis (Zamponi, 1977), from intertidal ecosystem through their morphogical and functional study. The species P. clematis has a circumscript sphincter of palmate type. This muscle is constituted by a mesogloeal axis and several mesogloeal subaxes. Axis as well as subaxes give a support to the endoderm which border is smooth. Aulactinia marplatensis has a circunscript sphincter pinnate type. The axis has a truncated cone shape while in P. clematis the shape is cylindrical on its origin and it is bifurcated at the end. Both species experiments were carried out using the isolated muscles. They were stimulated at increasing KCl concentrations ranging from 20 to 200 mM. The results were analysed in the form of dose-response curves expressed in tension in grams force vs concentration. Contractil force increases in a sigmoid form to increasing KCl concentrations. The correlation between morphology and function and the differences shown in both species would be related to their intertidal distribution.

Diet and functional feeding groups of Chironomidae (Diptera) in the Middle Paraná River floodplain (Argentina)

The gut contents of nine genera of benthic Chironominae and Tanypodinae from the Middle Paraná River floodplain habitats (a lake and a secondary channel) were analyzed to determine their feeding patterns and functional feeding groups. Amorphous detritus, animal and vegetal tissues, and mineral materials (predominantly sand) were observed in the larval guts. Amorphous detritus were the main food item found for Polypedilum (Tripodura) sp., Chironomus gr. decorus sp., Endotribelos sp., Phaenopsectra sp., Cladopelma sp., and Pelomus sp. (Chironominae), while animal tissues (mainly oligochaetes) were the most important food item found for Ablabesmyia (Karelia) sp., Coelotanypus sp., and Procladius sp. (Tanypodinae). Dietary overlap was calculated for all pairs of genera. Within predators, the highest overlap was obtained between Coelotanypus sp. and Ablabesmyia (Karelia) sp., while within detritivores the highest niche overlap was obtained between Endotribelos sp. and Phaenopsectra sp.

A Multi-state model for the analysis of functional decline and mortality of frail elderly patients

L’objectiu d’aquest estudi, que correspon a un projecte de recerca sobre la pèrdua funcional i la mortalitat de persones grans fràgils, és construir un procés de supervivència predictiu que tingui en compte l’evolució funcional i nutricional dels pacients al llarg del temps. En aquest estudi ens enfrontem a l’anàlisi de dades de supervivència i mesures repetides però els mètodes estadístics habituals per al tractament conjunt d’aquest tipus de dades no són apropiats en aquest cas. Com a alternativa utilitzem els models de supervivència multi-estats per avaluar l’associació entre mortalitat i recuperació, o no, dels nivells funcionals i nutricionals considerats normals. Després d’estimar el model i d’identificar els factors pronòstics de mortalitat és possible obtenir un procés predictiu que permet fer prediccions de la supervivència dels pacients en funció de la seva història concreta fins a un determinat moment. Això permet realitzar un pronòstic més precís de cada grup de pacients, la qual cosa pot ser molt útil per als professionals sanitaris a l’hora de prendre decisions clíniques.

Functional analysis of the murine T lymphocyte immune response to a protozoan parasite, Leishmania tropica

The results presented in this review summarize a seirs of experiments designed to characterize the murine T cell imune response to the protozoan parasite Leishmania tropica. Enriched T cell populations and T cell clones specific for L. tropica antigens were derived from lymph nodes of primed mice and maintained in continous culture in vitro. These T lymphocytes were shown (A) to express the Lyt 1+ 3- cell surface phenotype, (B) to proliferate specifically in vitro in response to parasite antigens, together with a source of irradiated syngeneic macrophages, (C) to transfer antigen-specific delayed-type hypersensitivity (DTH) responses to normal syngeneic mice, (D) to induce specific activation of parasitized macrophages in vitro resulting in the destruction of intracellular parasites, (E) to provide specific helper activity for antibody responses in vitro in a hapten-carrier system. Protection studies using these defiened T cell populations should allow the characterization of parasite antigen(s) implicated in the induction of cellular immune responses beneficial for the host.