La contrarrevolución del virrey Abascal: Lima, 1806-1816 (Estudios)

Durante los años del colapso de la monarquía española, el Virreinato del Perú estuvo gobernado por Fernando de Abascal, quien, en alianza con la élíte de Lima, aplicó una política de represión en términos ideológicos y militares ante cualquier intento separatista o revolucionario, tanto dentro de su jurisdicción virreinal como fuera de ella, entre cuyos territorios vecinos estaban Quito, Chile y Charcas. Asimismo, mediante esta estrategia, el Virreinato de Lima intentó recuperar parte de la influencia perdida en América del Sur como consecuencia de la aplicación de las reformas borbónicas, especialmente durante la segunda mitad del siglo XVIII. El presente artículo pone atención a la respuesta de Lima contra al movimiento insurgente desatado en Quito a partir de 1809.

Las relaciones diplomáticas entre García Moreno y la Santa Sede (1861-1866)

El presente texto busca dilucidar las tratativas diplomáticas entre García Moreno y la Santa Sede que ocurrieron entre el 1861 y 1866 y cuyo fin era conseguir el Concordato: un pacto que el Presidente ecuatoriano consideraba fundamental para la realización de su proyecto de reformas. Frente a un país lacerado por luchas internas y dividido entre sí, era necesario un cambio enérgico para establecer el orden social y la unión nacional. Paladino de la reforma debía ser, según García Moreno, el clero a su vez reformado y vuelto ejemplo de virtud para restituir el orden y la moral al país entero. Entonces, era primordial un Concordato con la Santa Sede para imponer la reforma del clero y establecer los límites entre poder religioso y estatal. No obstante el Concordato no representó una solución fácil e inmediata al cambio, en cuanto planteó una serie de contrastes, discusiones, reformulaciones y cambios que desvelaron los intereses que rodeaban al poder estatal y religioso en el país. En este contexto la Santa Sede iba a representar una fuente legitimadora del poder religioso, demostrando su preferencia en tratar las cuestiones con el Presidente ecuatoriano y su legítimo gobierno, marginando el parlamento. El Concordato resultó ser un documento que permitió a García Moreno fortalecer su control sobre la Iglesia ecuatoriana y mediar con la Santa Sede algunas cuestiones, sobre todo la inherente el diezmo, obteniendo una mayor ventaja económica para el Estado. Soluciones que, no fueron definitivas, sino que dejaron abierta la discusión para ulteriores tratativas.

Neotypification of Actaea pachypoda Elliott (Ranunculaceae)

Typification elements within the protologue of Actaea pachypoda Elliott are fully discussed. The absence of cited original material has led to our choice here of a suitable neotype in order to preserve current usage of the name.

Stephen Martin Leake: a Victorian's view of the Common Law

This article considers the life and work of Stephen Martin Leake and seeks to locate his work within the wider context of the procedural and substantive transformation of the mid-to-late Victorian legal world. In particular, the article attempts to rescue Leake from obscurity and emphasise his importance in this process. It is argued that Leake’s work began the process whereby common lawyers conceived of their law as organised in a principled rather than procedural manner. Later common law jurists built upon this work. Consideration is also given to the philosophical and jurisprudential sources upon which Leake drew in constructing his treatises.

A genome-wide association meta-analysis identifies new childhood obesity loci

Multiple genetic variants have been associated with adult obesity and a few with severe obesity in childhood; however, less progress has been made in establishing genetic influences on common early-onset obesity. We performed a North American, Australian and European collaborative meta-analysis of 14 studies consisting of 5,530 cases (≥95th percentile of body mass index (BMI)) and 8,318 controls (<50th percentile of BMI) of European ancestry. Taking forward the eight newly discovered signals yielding association with P < 5 × 10(-6) in nine independent data sets (2,818 cases and 4,083 controls), we observed two loci that yielded genome-wide significant combined P values near OLFM4 at 13q14 (rs9568856; P = 1.82 × 10(-9); odds ratio (OR) = 1.22) and within HOXB5 at 17q21 (rs9299; P = 3.54 × 10(-9); OR = 1.14). Both loci continued to show association when two extreme childhood obesity cohorts were included (2,214 cases and 2,674 controls). These two loci also yielded directionally consistent associations in a previous meta-analysis of adult BMI(1).

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Common variants at only two loci, FTO and MC4R, have been reproducibly associated with body mass index (BMI) in humans. To identify additional loci, we conducted meta-analysis of 15 genome-wide association studies for BMI (n > 32,000) and followed up top signals in 14 additional cohorts (n > 59,000). We strongly confirm FTO and MC4R and identify six additional loci (P < 5 x 10(-8)): TMEM18, KCTD15, GNPDA2, SH2B1, MTCH2 and NEGR1 (where a 45-kb deletion polymorphism is a candidate causal variant). Several of the likely causal genes are highly expressed or known to act in the central nervous system (CNS), emphasizing, as in rare monogenic forms of obesity, the role of the CNS in predisposition to obesity.

The Stephen Dwoskin dossier: introduction

This dossier aims to consider the contribution Stephen Dwoskin and his work made to the development of film and its infrastructure in the UK from 1964 when he arrived in the London until his death in 2012. Dwoskin not only straddled different contexts and ideologies about film but advocated for the support of work in a wide variety of forms. Because of this he was not easily categorizeable. Much of the work analyzing his camera work and his contribution to film is written in French and there is little, particularly in recent years, in English. As such this dossier constituted an important contribution to the reassessment of a singular avant-garde artist and film maker. (can I use avant garde here?) In the light of his recent death this is a timely moment for a consideration of Dwoskin’s achievements and legacy. As well as having a groundbreaking vision of what film could do, he was an influential figure and constituting force in terms of the milieu and structures that supported the independent film world in the UK for several decades. Much of the literature surrounding this world in the UK has been formed by key figures making sense of their part in history. This dossier aims towards some first steps in historicising his legacy. Two of the proposed texts will be making use of new material to conduct original research made available through the recently acquired Dwoskin Archive at University of Reading. Due to Dowksin’s heterogenous involvement in film, there are many ways in which Dwoskin can be considered and the proposed essays will take a range of perspectives to assess and analyse his contribution.

A Reading by Tapscott Stephen

A reading delivered at Colby College on January 1, 1981.

A Reading by Stephen Tapscott

A reading delivered at Colby College on January 1, 1981.