Failure Detectors in Homonymous Distributed Systems (with an Application to Consensus).

This paper is on homonymous distributed systems where processes are prone to crash failures and have no initial knowledge of the system membership (?homonymous? means that several processes may have the same identi?er). New classes of failure detectors suited to these systems are ?rst de?ned. Among them, the classes H? and H? are introduced that are the homonymous counterparts of the classes ? and ?, respectively. (Recall that the pair h?,?i de?nes the weakest failure detector to solve consensus.) Then, the paper shows how H? and H? can be implemented in homonymous systems without membership knowledge (under different synchrony requirements). Finally, two algorithms are presented that use these failure detectors to solve consensus in homonymous asynchronous systems where there is no initial knowledge ofthe membership. One algorithm solves consensus with hH?, H?i, while the other uses only H?, but needs a majority of correct processes. Observe that the systems with unique identi?ers and anonymous systems are extreme cases of homonymous systems from which follows that all these results also apply to these systems. Interestingly, the new failure detector class H? can be implemented with partial synchrony, while the analogous class A? de?ned for anonymous systems can not be implemented (even in synchronous systems). Hence, the paper provides us with the ?rst proof showing that consensus can be solved in anonymous systems with only partial synchrony (and a majority of correct processes).

Regional and seasonal patterns of litterfall in tropical South America

The production of aboveground soft tissue represents an important share of total net primary production in tropical rain forests. Here we draw from a large number of published and unpublished datasets (n = 81 sites) to assess the determinants of litterfall variation across South American tropical forests. We show that across old-growth tropical rainforests, litterfall averages 8.61±1.91Mgha?1 yr?1 (mean±standard deviation, in dry mass units). Secondary forests have a lower annual litterfall than old-growth tropical forests with a mean of 8.01±3.41Mgha?1 yr?1. Annual litterfall shows no significant variation with total annual rainfall, either globally or within forest types. It does not vary consistently with soil type, except in the poorest soils (white sand soils), where litterfall is significantly lower than in other soil types (5.42±1.91Mgha?1 yr?1). We also study the determinants of litterfall seasonality, and find that it does not depend on annual rainfall or on soil type. However, litterfall seasonality is significantly positively correlated with rainfall seasonality. Finally, we assess how much carbon is stored in reproductive organs relative to photosynthetic organs. Mean leaf fall is 5.74±1.83Mgha?1 yr?1 (71% of total litterfall). Mean allocation into reproductive organs is 0.69±0.40Mgha?1 yr?1 (9% of total litterfall). The investment into reproductive organs divided by leaf litterfall increases with soil fertility, suggesting that on poor soils, the allocation to photosynthetic organs is prioritized over that to reproduction. Finally, we discuss the ecological and biogeochemical implications of these results.

Nuclear translocation of NF-κB is increased in dopaminergic neurons of patients with Parkinson disease

Evidence from postmortem studies suggest an involvement of oxidative stress in the degeneration of dopaminergic neurons in Parkinson disease (PD) that have recently been shown to die by apoptosis, but the relationship between oxidative stress and apoptosis has not yet been elucidated. Activation of the transcription factor NF-κB is associated with oxidative stress-induced apoptosis in several nonneuronal in vitro models. To investigate whether it may play a role in PD, we looked for the translocation of NF-κB from the cytoplasm to the nucleus, evidence of its activation, in melanized neurons in the mesencephalon of postmortem human brain from five patients with idiopathic PD and seven matched control subjects. In PD patients, the proportion of dopaminergic neurons with immunoreactive NF-κB in their nuclei was more than 70-fold that in control subjects. A possible relationship between the nuclear localization of NF-κB in mesencephalic neurons of PD patients and oxidative stress in such neurons has been shown in vitro with primary cultures of rat mesencephalon, where translocation of NF-κB is preceded by a transient production of free radicals during apoptosis induced by activation of the sphingomyelin-dependent signaling pathway with C2-ceramide. The data suggest that this oxidant-mediated apoptogenic transduction pathway may play a role in the mechanism of neuronal death in PD.