999 resultados para Blasio, José Luis,-1842-1928. Maximiliano íntimo


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Presenta los principales aspectos estadísticos de la pesquería marítima peruana durante el año de 1967. Así mismo, incluye aspectos relacionados con la industrialización de los productos de la pesca marítima, consumo fresco, flota pesquera, plantas industriales, inversiones, personal ocupado y comercio exterior.

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This paper studies two important reasons why people violate procedure invariance, loss aversion and scale compatibility. The paper extends previous research on loss aversion and scale compatibility by studying loss aversion and scale compatibility simultaneously, by looking at a new decision domain, medical decision analysis, and by examining the effect of loss aversion and scale compatibility on "well-contemplated preferences." We find significant evidence both of loss aversion and scale compatibility. However, the sizes of the biases due to loss aversion and scale compatibility vary over trade-offs and most participants do not behave consistently according to loss aversion or scale compatibility. In particular, the effect of loss aversion in medical trade-offs decreases with duration. These findings are encouraging for utility measurement and prescriptive decision analysis. There appear to exist decision contexts in which the effects of loss aversion and scale compatibility can be minimized and utilities can be measured that do not suffer from these distorting factors.

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This paper tests the internal consistency of time trade-off utilities.We find significant violations of consistency in the direction predictedby loss aversion. The violations disappear for higher gauge durations.We show that loss aversion can also explain that for short gaugedurations time trade-off utilities exceed standard gamble utilities. Ourresults suggest that time trade-off measurements that use relativelyshort gauge durations, like the widely used EuroQol algorithm(Dolan 1997), are affected by loss aversion and lead to utilities thatare too high.

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This paper presents a test of the predictive validity of various classes ofQALY models (i.e., linear, power and exponential models). We first estimatedTTO utilities for 43 EQ-5D chronic health states and next these states wereembedded in health profiles. The chronic TTO utilities were then used topredict the responses to TTO questions with health profiles. We find that thepower QALY model clearly outperforms linear and exponential QALY models.Optimal power coefficient is 0.65. Our results suggest that TTO-based QALYcalculations may be biased. This bias can be avoided using a power QALY model.

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Analiza las estadísticas de la pesquería marítima peruana que publica el Instituto del Mar del Perú IMARPE y que corresponde al año 1965. Bajo las siguientes fuentes de información: inspectores de pesca, capitanías de puertos, empresas pesqueras, terminales pesqueros de Lima y Callao y Superintendencia general de Aduanas.

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Analiza estadísticas de desembarque para determinar el valor de la producción por especies en cada puerto; para la determinación del valor dela producción por especies se contó con las fuentes de información de los inspectores de Pesca del Instituto del mar, Capitanías de Puertos, Terminales Pesqueros de Lima y Callao y Oficina Sectorial de Planificación Pesquera.

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In cost-effectiveness analysis (CEA) it is usually assumed that a QALY is of equal value to everybody, irrespective of the patient's age. However, it is possible that society assigns different social values to a QALY according to who gets it. In this paper we discuss the possibility of weighting health benefits for age in CEA. We also examinethe possibility that age-related preferences depend on the size of the health gain. An experiment was performedto test these hypotheses. The results assessing suggest that the patient's age is a relevant factor when assessing health gains.

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Starting from a finite or countable set of states of health, and assumingthe existence of an objective transitive preference relation on that set,we propose a way of performing interpersonal comparisons of states ofhealth. In so doing, we first consider the population divided into types,and consider that two individuals of a different type have a comparablestate of health whenever they sit at the same centile of their respectivetype. A way of comparing and evaluating states of health for differentgroups is then proposed and rationalized. This can be viewed as both analternative and an extension of the traditional QALY approach.

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La idea de este Proyecto Fin de Máster es la creación de una nueva línea de negocio compuesta por servicios basados en software libre para la empresa Efedos Consulting.

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Rhodometra sacraria (Linnaeus), a cosmopolitan sterrhine confirmed from Chile (Lepidoptera, Geometridae). Rhodometra sacraria (Linnaeus, 1767), corologically a cosmopolitan species, is documented from Chile thanks to the analysis of specimens from four different localities in that country, at the same time, increasing the number of species known from the subfamily Sterrhinae in Chile, as well as being only the second (confirmed) documentation of this species from the Neotropics.

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BACKGROUND: The only known albino gorilla, named Snowflake, was a male wild born individual from Equatorial Guinea who lived at the Barcelona Zoo for almost 40 years. He was diagnosed with non-syndromic oculocutaneous albinism, i.e. white hair, light eyes, pink skin, photophobia and reduced visual acuity. Despite previous efforts to explain the genetic cause, this is still unknown. Here, we study the genetic cause of his albinism and making use of whole genome sequencing data we find a higher inbreeding coefficient compared to other gorillas.RESULTS: We successfully identified the causal genetic variant for Snowflake's albinism, a non-synonymous single nucleotide variant located in a transmembrane region of SLC45A2. This transporter is known to be involved in oculocutaneous albinism type 4 (OCA4) in humans. We provide experimental evidence that shows that this amino acid replacement alters the membrane spanning capability of this transmembrane region. Finally, we provide a comprehensive study of genome-wide patterns of autozygogosity revealing that Snowflake's parents were related, being this the first report of inbreeding in a wild born Western lowland gorilla.CONCLUSIONS: In this study we demonstrate how the use of whole genome sequencing can be extended to link genotype and phenotype in non-model organisms and it can be a powerful tool in conservation genetics (e.g., inbreeding and genetic diversity) with the expected decrease in sequencing cost.

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Currently there are many standards that deal with accessibility issues regarding users’ models, learning scenarios, interaction preferences, devices capabilities, metadata for specifying the delivery of any resource to meet users’ needs, and software accessibility and usability. It is difficult to understand the existing relationships between these standards, as each one represents a different viewpoint and thus has its own sets of goals and scope. This paper gives an overview on existing standards addressing accessibility, usability and adaptation issues in e-learning, and discusses their application to cope with the objectives of the A2UN@ project, which focuses on attending the accessibility and adaptation needs for ALL in Higher Education

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El Graduado Superior en Diseño (GSD) de la Universitat Politècnica de Catalunya, está basado en un modelo de aprendizaje combinado, en el cual las nuevas tecnologías representan una oportunidad para la enseñanza y ofrecen al usuario independencia para aprender rápidamente y para poder acceder a más recursos. Este tipo de aprendizaje no está fundamentado en un único modelo de aprendizaje o basado en una teoría general, sino en la aplicación de un pensamiento ecléctico y práctico, el cual lo hace una opción adecuada para la enseñañnza del diseño. El propósito de este artículo es explicar la investigación y la práctica realizada a través de los 5 años en los cuales se han integrado las ventajas de la enseñañnza tradicional y el uso de las nuevas tecnologías. Finalmente el artículo concluye describiendo el futuro del curso.

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Fascination is a project for design students, developed jointly by the Technical University of Catalonia (UPC) and the University of Technology Thonburi (KMUTT), which works with two groups of students, one group of participants in Spain and another group in Thailand where, hands-on activities, a range of technologies are used to prepare students for the lessons, through learning activities and content. This research paper presents the test of both a general model and a tool for measuring the participants’ experiences in a course that uses a blended learning methodology, with the aim of collecting empirical evidence to justify the effort of applying this methodology, based on the participants’ satisfaction. The procedure used in the conceptualization of the survey, the generation of topics, the collection of data, and the validation of the scale of various items are described here. The information, provided by the 26 people surveyed about the course and the virtual environment that was used, was analyzed to measure their perceptions and explore possible relations. Finally the conclusions of the research and the future work are presented.

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La comunicació mòbil és un dels temes de més actualitat en diferents fòrums, des de diferents perspectives. Espanya juga un paper important per les dinàmiques i l’evolució del seu mercat. En aquest sentit, el nostre país ofereix un interès específic per l'amplitud del seu parc de dispositius 3G (el segon d'Europa, després d'Itàlia) i per la intensitat del desenvolupament de xarxes socials mòbils, a més de per la creixent implicació d'empreses en la producció i distribució de continguts mòbils. Com va passar amb Internet, es tracta d’un procés d'innovació pel qual els formats de contingut, les pràctiques de consum i els models de negoci característics de la televisió i la xarxa, per exemple, s'adapten, primer, al nou mitjà, per a després desenvolupar formes i models específics que aprofiten les potencialitats de personalització, geolocalització i conectivitat ubiqua.