1953 University of Michigan Football Team (full Squad)

Top Row: Ted Kress, Dave Williams, William McKinley, Larry Cox, Dave Hill, Dick Kolesar, Van Schoick, Earl Johnson, Bob Ames.

6th Row: Tony Branoff, Ed Hickey, Don Bennett, Dick Vorenkamp, Tom Hendricks, Doug Murray, Charles Ritter, Mike Orend, Carl Kamhout, Jim Kirby, Joe Krahl.

5th Row: Don Dugger, Jack Wheeler, Wilbur Brown, Jerry Gonser, Bob Sriver, Jim Bates, Ray Donohoe, Dick Strozewski, Dave Rentschler, John Kuchka, George Corey, Phil Endres.

4h Row: Gerry Williams, Gordon Barnes, Edgar Meads, Charles Krahnke, Fred Baer, Stanley Knickerbocker, Jim Fox, John Peckham, John Morrow, Dick Rex, Coach J. T. White.

3rd Row: Coach Don Robinson, Don Drake, Joe Shomsky, Lou Baldacci, Salvatore DiMucci, George Dutter, Ray Kenaga, George Muellich, Jim Bowman, Ted Cachey, Coach Bill Orwig.

2nd Row: Cliff Keen, Dean Ludwig, Duncan McDonald, Ken Shields, Peri Gagalis, Pete Wolgast, Bob Milligan, Ron Geyer, Dick Beison, Dan Cline, Art Walker, Coach Matt Patanelli.

Front Row: Wally Weber, John Veselenak, Tad Stanford, Gene Knutson, Dick Balzhiser, Captain Dick O'Shaughnessy; Head Coach Bennie Oosterbaan; Bob Marion, Bob Topp, Ray VanderZeyde, Ron Williams, Jim Balog, Jack Blott.

1952 UM Football Team, full squad photo

Front Row: William Billings, Tony Branoff, Richard Beison, Robert Topp, Donald Bennett, Merritt Green, Captain, Charles Ritter, Theodore Kress, Richard Strozewski, Cark Kamhout

Second Row: Ronald Williams, James Balog, Ray VanderZeyde, Robert Hurley, Joseph Shomsky, Robert Milligan, Stanley Knickerbocker, James Bowman, Melvin Bernay, Kenneth Shields, Casimir Chomicz

Third Row: Dean Ludwig, Donald Drake, Norman Canty, Richard Balzhiser, Junior Steilstra, James Dutcher, Robert Dingman, Peri Gagalis, Eugene Knutson, Donald Oldham, Lowell Perry

Fourth Row: Edward Hickey, Duncan MacDonald, Stanley Bowns, Daniel Cline, George Muelich, Herbert Geyer, Russell Swaney, George Dutter, Fred Caffrey, Robert Timm

Fifth Row: John Veselenak, Thad Stanford, Richard O'Shaughnessy, Captain-elect, Donald Evans, Ralph Stribe, Richard Rex, Russell Rescorla, James Wagner, Donald Dugger, Laurence LeClaire

Sixth Row: Donald Zanfagna, Theodore Topor, James Bates, Wayne Melchiori, Robert Matheson, Bruce Bartholomew, Bernhardt Pederson, Roger Zatkoff, Thomas Witherspoon

Back Row: John Treadway, Ted Cachey, Fred Baer, Ray Kenaga, John Rahrig, Arthur Walker, Frank Hall, David Tinkham

1953 University of Michigan Football Team (full Squad)

Top Row: Ted Kress, Dave Williams, William McKinley, Larry Cox, Dave Hill, Dick Kolesar, Van Schoick, Earl Johnson, Bob Ames.

6th Row: Tony Branoff, Ed Hickey, Don Bennett, Dick Vorenkamp, Tom Hendricks, Doug Murray, Charles Ritter, Mike Orend, Carl Kamhout, Jim Kirby, Joe Krahl.

5th Row: Don Dugger, Jack Wheeler, Wilbur Brown, Jerry Gonser, Bob Sriver, Jim Bates, Ray Donohoe, Dick Strozewski, Dave Rentschler, John Kuchka, George Corey, Phil Endres.

4h Row: Gerry Williams, Gordon Barnes, Edgar Meads, Charles Krahnke, Fred Baer, Stanley Knickerbocker, Jim Fox, John Peckham, John Morrow, Dick Rex, Coach J. T. White.

3rd Row: Coach Don Robinson, Don Drake, Joe Shomsky, Lou Baldacci, Salvatore DiMucci, George Dutter, Ray Kenaga, George Muellich, Jim Bowman, Ted Cachey, Coach Bill Orwig.

2nd Row: Cliff Keen, Dean Ludwig, Duncan McDonald, Ken Shields, Peri Gagalis, Pete Wolgast, Bob Milligan, Ron Geyer, Dick Beison, Dan Cline, Art Walker, Coach Matt Patanelli.

Front Row: Wally Weber, John Veselenak, Tad Stanford, Gene Knutson, Dick Balzhiser, Captain Dick O'Shaughnessy; Head Coach Bennie Oosterbaan; Bob Marion, Bob Topp, Ray VanderZeyde, Ron Williams, Jim Balog, Jack Blott.

Famous guns from the Winchester Collection.

Mode of access: Internet.

Poems on several occasions.

Contains "Night", a poem in imitation of Milton.

The history of Richmond, in the county of York; including a description of the castle, friary, Easeby-abbey, and other remains of antiquity in the neighbourhood.

Published anonymously. Author's name appears in edition of 1821.

Questions, exercises, and notes on Robinson's Elementary law,

Mode of access: Internet.

Ogden's revised California real property law /

Kept up to date by pamphlet supplements.

Evaluating JTPA programs for economically disadvantaged adults : a case study of Utah and general findings /

Mode of access: Internet.

All hail solidarity /

Mode of access: Internet.

Delayed traveling ionospheric disturbances, especially in equatorial regions, following geomagnetic activity

For the Western-Pacific region spread-F has been found to occur with delays after geomagnetic activity (GA) ranging from 5 to 10 days as station groups are considered from low midlatitudes to equatorial regions. The statistical (superposed-epoch) analyses also indicate that at the equator the spread-F, and therefore associated medium-scale traveling ionospheric disturbances (MS-TIDs) occur with additional delays around 16, 22 and 28 days representing a 6-day modulation of the delay period. These results are compared with similar delays, including the modulation, for D-region enhanced hydroxyl emission (Shefov, 1969). It is proposed that this similarity may be explained by MS-TIDs influencing both the F and D regions as they travel. Long delays of over 20 days are also found near the equator for airglow-measured MS-TIDs (Sobral et al., 1997). These are recorded infrequently and have equatorward motions, while normally eastward motions are measured at the equator. Also in midlatitudes D-region absorption events have been shown (statistically) to have similar long delays after GA. It is suggested that atmospheric gravity waves and associated MS-TIDs may be generated by some of the precipitations responsible for the absorption. The recording of the delayed spread-F events depends on the GA being well below the average levels around sunset on the nights of recording. This implies that lower upper-atmosphere neutral particle densities are necessary.

Influence of geomagnetic activity on the occurrence of midlatitude ionogram-recorded spread-F

Delayed spread-F occurrence as recorded by ionograms, following geomagnetic activity (GA) has been investigated using data from 88 stations located around the world. The spread-F occurrence is delayed progressively from one to three days, from subauroral to midlatitude regions. The equatorial latitudes show suppressed activity. An examination of daily spread-F occurrence values relative to the AE index reveals not only a main delay of one day, but also delays of two and three days. These delays involve principally GA occurring around 0600 hrs LT.

Sunflower trypsin inhibitor-1

SFTI-1 is a bicyclic 14 amino acid peptide that was originally isolated from the seeds of the sunflower Helianthus annuus. It is a potent inhibitor of trypsin, with a sub-nanomolar K, value and is homologous to the active site region of the well-known family of serine protease inhibitors known as the Bowman-Birk trypsin inhibitors. It has a cyclic backbone that is cross-braced by a single disulfide bridge and a network of hydrogen bonds that result in a well-defined structure. SFTI-1 is amenable to chemical synthesis, allowing for the creation of synthetic variants. Alterations to the structure such as linearising the backbone or removing the disulfide bridge do not reduce the potency of SFTI-1 significantly, and minimising the peptide to as few as nine residues results in only a small decrease in reactivity. The creation of linear variants of SFTI-1 also provides a tool for investigating putative linear precursor peptides. The mechanism of biosynthesis of SFTI-1 is not yet known but it seems likely that it is a gene-coded product that has arisen from a precursor protein that may be evolutionarily related to classic Bowman-Birk inhibitors.

Discovery, structural determination, and putative processing of the precursor protein that produces the cyclic trypsin inhibitor sunflower trypsin inhibitor 1

Backbone-cyclized proteins are becoming increasingly well known, although the mechanism by which they are processed from linear precursors is poorly understood. In this report the sequence and structure of the linear precursor of a cyclic trypsin inhibitor, sunflower trypsin inhibitor 1 (SFTI-1) from sunflower seeds, is described. The structure indicates that the major elements of the reactive site loop of SFTI-1 are present before processing. This may have importance for a protease-mediated cyclizing reaction as the rigidity of SFTI-1 may drive the equilibrium of the reaction catalyzed by proteolytic enzymes toward the formation of a peptide bond rather than the normal cleavage reaction. The occurrence of residues in the SFTI-1 precursor susceptible to cleavage by asparaginyl proteases strengthens theories that involve this enzyme in the processing of SFTI-1 and further implicates it in the processing of another family of plant cyclic proteins, the cyclotides. The precursor reported here also indicates that despite strong active site sequence homology, SFTI-1 has no other similarities with the Bowman-Birk trypsin inhibitors, presenting interesting evolutionary questions.

Risk of non-small cell lung cancer and the cytochrome P4501A1 Ile462Val polymorphism

Objective: The Ile462Val substitution in the cytochrome P450 1A1 gene (CYP1A1) results in increased enzymatic activity. Preliminary data suggesting a link between this polymorphism and lung cancer risk in Caucasians are inconsistent, reflecting small sample sizes and the relatively low frequency of the variant. Methods: The data set consisted of 1050 primary non-small cell lung cancer cases and 581 controls, a large homogenous population designed specifically to address previous inconsistencies. Patients were genotyped using a PCR-RFLP technique. Results: Carriers of the valine allele, CYP1A1*2C, (Ile/Val or Val/Val genotypes) were significantly over-represented in non-small cell lung cancer compared to controls (OR=1.9; 95% CI=1.2-2.9; p=0.005) when adjusted for confounders, particularly in women (OR=4.6; 95% CI=1.7-12.4; p=0.003). The valine variant was statistically significantly over-represented in cases of lung cancer younger than the median age (64 years) (OR=2.5; 95% CI=1.3-4.8; p=0.005) and cases with less than the median cumulative tobacco-smoke exposure (46 pack-years) (OR=2.4; 95% CI=1.3-4.7; p=0.007). Conclusions: These new data establish an association between the CYP1A1 Ile462Val polymorphism and the risk of developing non-small cell lung cancer, especially among women.