Last Will and Testament - Deborah Clow

Probate of the Last Will and Testament of Deborah Clow of the Township of Stamford. Richard Woodruff is the executor. Deborah bequeathed 1/2 of 63 acres of land in Stamford to her friend William Woodruff of St. Davids. The other 1/2 of the land belonged to her sister Levina Wilkinson - instrument no. 3638, Setepmber 4.

Probate of Last Will and Testament - William Smith

Probate of Last Will and Testament of William Smith of the township of Lincoln. Mr. Smith was a farmer. His goods and chattels are left to his children and grandchildren. The document was registered May 9, 1865 - instrument no. 15383 and the original date of the document is January 20, 1856.

Last Will and Testament - Angus Shaw

Last Will and Testament of Angus Shaw of Montreal. He leaves his possessions to Marjory Shaw, his wife; children of his sister Marion (wife of Duncan McDougall) and his nieces who are daughters of his deceased sister Isabella, May 9, 1809.

Notice of Will - James Middough

Notice regarding the late James Middough that anything concerning his will is granted to William Woodruff and Richard Woodruff (merchants) executors of the will, August 3, 1839.

Last Will and Testament - David Clow

Last Will and Testament (copy) of David Clow of the Township of Stamford. Richard and William Woodruff are listed as executors. Attached to this will is a document stating that this is a true copy of the will, Sept. 12, 1839.

Last Will and Testament - Richard Woodruff

Last Will and Testament of Richard Woodruff of St. Davids. This is a printed copy which is unsigned, June 15, 1872.

Last Will and Testament - John Picard

Last Will and Testament of John Picard of the township of Niagara. He leaves his land which consists of part of Lot 113 in the township of Niagara to Annie Mariah Steel. The executors are John Stevens and Gilbert Anderson. The document was registered July 3, 1882 – instrument no. 1743, May 9, 1882.

Last Will and Testament - Samuel DeVeaux Woodruff

Last Will and Testament of Samuel DeVeaux Woodruff received by the central office in Nov. of 1906 and April 1907. In pencil it is written that the document is from Aug. 2, 1902.

The Arabidopsis NPR1 Protein Is a Receptor for the Plant Defense Hormone Salicylic Acid

Systemic Acquired Resistance (SAR) is a type of plant systemic resistance occurring against a broad spectrum of pathogens. It can be activated in response to pathogen infection in the model plant Arabidopsis thaliana and many agriculturally important crops. Upon SAR activation, the infected plant undergoes transcriptional reprogramming, marked by the induction of a battery of defense genes, including Pathogenesis-related (PR) genes. Activation of the PR-1 gene serves as a molecular marker for the deployment of SAR. The accumulation of a defense hormone, salicylic acid (SA) is crucial for the infected plant to mount SAR. Increased cellular levels of SA lead to the downstream activation of the PR-1 gene, triggered by the combined action of the Non-expressor of Pathogenesis-related Gene 1 (NPR1) protein and the TGA II-clade transcription factor (namely TGA2). Despite the importance of SA, its receptor has remained elusive for decades. In this study, we demonstrated that in Arabidopsis the NPR1 protein is a receptor for SA. SA physically binds to the C-terminal transactivation domain of NPR1. The two cysteines (Cys521 and Cys529), which are important for NPR1’s coactivator function, within this transactivation domain are critical for the binding of SA to NPR1. The interaction between SA and NPR1 requires a transition metal, copper, as a cofactor. Our results also suggested a conformational change in NPR1 upon SA binding, releasing the C-terminal transactivation domain from the N-terminal autoinhibitory BTB/POZ domain. These results advance our understanding of the plant immune function, specifically related to the molecular mechanisms underlying SAR. The discovery of NPR1 as a SA receptor enables future chemical screening for small molecules that activate plant immune responses through their interaction with NPR1 or NPR1-like proteins in commercially important plants. This will help in identifying the next generation of non-biocidal pesticides.

Probate of Last Will and Testament of Alexander Simpson of Crowland Township

Probate of Last Will and Testament of Alexander Simpson of Crowland Township, January 29, 1872.

Probate (copy) of the Last Will and Testament of Thomas Clark Street of Stamford Township

Probate (copy) of the Last Will and Testament of Thomas Clark Street of Stamford Township. This is a printed copy which is signed by Charles A. Mittleberger, student at law, Oct. 18, 1872.

Last Will and Testament - Jane Caroline Woodruff (1903)

Last Will and Testament of Jane Caroline Woodruff in which she lists personal items to be left to her children, grandchildren, and nieces. [This appears to be a rough copy], December 31, 1903.

Last Will and Testament - Jane Caroline Woodruff (1910)

Last Will and Testament of Jane C. Woodruff. This is a handwritten copy of the previous Jane C. Woodruff will, June 15, 1910.

Statement signed by Hume Blake who has read the will of Joseph Clement and the will of Mary M. Clement

Statement signed by Hume Blake of Toronto (2 ½ pages) who has read the will of Joseph Clement dated May 14, 1810 and has also read the will of Mary M. Clement dated Sept. 10, 1842. He states that the devise to James D. Clement and Joseph Clement is void. “The executor therefore take the personal estate … and the lands devised to James and Joseph Clement descend unencumbered to the heir of the testator Joseph Clement.” This document is slightly burned on the edges but text is not affected. The outer page says “Mr. Hume Blake for Brock Woodruff, May 9, 1845.

Probate of the Last Will and Testament of Joseph Clement

Probate of the Last Will and Testament of Joseph Clement of the Township of Niagara, May 14, 1810 but it is noted that this is a copy of the original will and this copy was filed on Feb. 26, 1815, Nov. 25, 1875. This is accompanied by an envelope addressed to Sheriff Woodruff and postmarked Hamilton, Nov. 25, 1875.