Audit report on the Iowa Turkey Marketing Council for the years ended December 31, 2009 and 2008

Audit report on the Iowa Turkey Marketing Council for the years ended December 31, 2009 and 2008

Report on a special investigation of the Region 4 Fusion Office in Atlantic, Iowa for the period March 1, 2006 through August 31, 2009

Report on a special investigation of the Region 4 Fusion Office in Atlantic, Iowa for the period March 1, 2006 through August 31, 2009

The Iowa Perinatal Letter, July, August, September 2010, Vol. 31, no. 3

This newsletter from The Department of Public Health about perinatal health care and statistics.

Rebuild Iowa Office Federal Recovery Framework Recommendations, Updated August 31, 2010.

The Rebuild Iowa Office and its' state and local partners recommendations about improving and streamlining the state and federal disaster recovery framework.

Report on the Department of Commerce, Alcoholic Beverages Division for the month ended May 31, 2010

Report on the Department of Commerce, Alcoholic Beverages Division for the month ended May 31, 2010

Human natural Treg microRNA signature: role of microRNA-31 and microRNA-21 in FOXP3 expression.

Treg are the main mediators of dominant tolerance. Their mechanisms of action and applications are subjects of considerable debate currently. However, a human microRNA (miR) Treg signature has not been described yet. We investigated human natural Treg and identified a signature composed of five miR (21, 31, 125a, 181c and 374). Among those, two were considerably under-expressed (miR-31 and miR-125a). We identified a functional target sequence for miR-31 in the 3' untranslated region (3' UTR) of FOXP3 mRNA. Using lentiviral transduction of fresh cord blood T cells, we demonstrated that miR-31 and miR-21 had an effect on FOXP3 expression levels. We showed that miR-31 negatively regulates FOXP3 expression by binding directly to its potential target site in the 3' UTR of FOXP3 mRNA. We next demonstrated that miR-21 acted as a positive, though indirect, regulator of FOXP3 expression. Transduction of the remaining three miR had no direct effect on FOXP3 expression or on the phenotype and will remain the subject of future investigations. In conclusion, not only have we identified and validated a miR signature for human natural Treg, but also unveiled some of the mechanisms by which this signature was related to the control of FOXP3 expression in these cells.

Report on the City of Truesdale for the period July 1, 2006 through December 31, 2010

Report on the City of Truesdale for the period July 1, 2006 through December 31, 2010

Agreed upon procedures report on the City of Lohrville, Iowa for the period December 1, 2008 through October 31, 2010

Agreed upon procedures report on the City of Lohrville, Iowa for the period December 1, 2008 through October 31, 2010

Iowa Office of the State Medical Examiner Newsletter, October 31, 2007, no. 3

The official newsletter of the Iowa Office of the State Medical Examiner.

Audit report on the Iowa Corn Promotion Board for the years ended August 31, 2010 and 2009

Audit report on the Iowa Corn Promotion Board for the years ended August 31, 2010 and 2009

Fums desiguals. Comentari a la STSJC, Sala Civil i Penal, 31.3.2008 (MP: Ma. Eugènia Alegret Burgués)

L'objecte del plet són els requisits necessaris per a la instal·lació d¿una xemeneia per a l'evacuació dels fums del local situat en els baixos d'un edifici en règim de propietat horitzontal. La matèria no és nova, però la STSJC de 31 de març de 2008 suposa un canvi de criteri jurisprudencial en relació amb la STSJC de 15 de gener de 2005, que la Sala ha de justificar per evitar la infracció del principi d¿igualtat en l¿aplicació de la llei.

Special investigation of the City of Modale Volunteer Fire Department for the period January 1, 2006 through January 31, 2010

Special investigation of the City of Modale Volunteer Fire Department for the period January 1, 2006 through January 31, 2010

Miles of Public Roads in Iowa by Surface Type, December 31, 2009

Public roads by surface type in Iowa by Iowa Department of Transportation.