Exhumation history of the NW Indian Himalaya revealed by fission track and 40Ar/39Ar ages

New fission track and Ar/Ar geochronological data provide time constraints on the exhumation history of the Himalayan nappes in the Mandi (Beas valley) - Tso Monad transect of the NW Indian Himalaya. Results from this and previous studies suggest that the SW-directed North Himalayan nappes were emplaced by detachment from the underthrusted upper Indian crust by 55 Ma and metamorphosed by ca. 48-40 Ma. The nappe stack was subsequently exhumed to shallow upper crustal depths (<10 km) by 40-30 Ma in the Tso Monad dome (northern section of the transect) and by 30-20 Ma close to frontal thrusts in the Baralacha La region. From the Oligocene to the present, exhumation continued slowly.

The challenge of modeling nuclear receptor regulatory networks in mammalian cells.

Nuclear receptors are a major component of signal transduction in animals. They mediate the regulatory activities of many hormones, nutrients and metabolites on the homeostasis and physiology of cells and tissues. It is of high interest to model the corresponding regulatory networks. While molecular and cell biology studies of individual promoters have provided important mechanistic insight, a more complex picture is emerging from genome-wide studies. The regulatory circuitry of nuclear receptor regulated gene expression networks, and their response to cellular signaling, appear highly dynamic, and involve long as well as short range chromatin interactions. We review how progress in understanding the kinetics and regulation of cofactor recruitment, and the development of new genomic methods, provide opportunities but also a major challenge for modeling nuclear receptor mediated regulatory networks.

Suomen kirkon 800-vuotisjuhlassa (Valtioneuvoston tervehdys Turun Tuomiokirkossa 19.5.1955)

Puhe

Nurses, nursing technicians and assistants: who experiences more moral distress?

Objective: To identify the frequency and intensity of moral distress experienced by nurses, technicians and nursing assistants who worked in hospitals in the South of Rio Grande do Sul State. Method: A survey research was conducted with 334 nursing workers from three institutions, through a questionnaire of moral distress. Constructs were validated through factorial analysis and Cronbach’s alpha: lack of competence of the working team, disrespect to the patient’s autonomy, insufficient working conditions and therapeutic obstinacy. Results: With descriptive statistics and analysis of variance, it was found that nurses and nursing assistants have higher perception of moral distress when compared to nursing technicians. Organizational questions and ways of communication influence lower perception of moral distress.Conclusion: Implementation of actions to favor coping, decision making and autonomy exercise from those workers.


Conciliação entre Vida Profissional e Familiar em Cabo Verde. O Papel do Estado e das Famílias

O mundo contemporâneo tem demonstrado, nas últimas décadas, que as sociedades são confrontadas e atravessadas por transformações profundas das estruturas sociais a grande dimensão, gerando mutações na organização do trabalho e da vida familiar, adquirindo formas diversas, consoante os contextos e locais. O forte aumento da participação das mulheres no mercado de trabalho teve um impacto decisivo na reconfiguração familiar, tanto na esfera pública como na esfera privada, com consequências muito expressivas nas formas de articulação entre a vida profissional e familiar. Tanto o modelo do homem provedor foi posto em causa, como as formas actuais de divisão familiar de trabalho revelam assimetrias entre os casais e a evolução do modelo de duplo emprego. Esta investigação, analisa a problemática da conciliação vida familiar e trabalho na sociedade Cabo-verdiana, debruçando-se especificamente sobre as estratégias que os indivíduos utilizam, tendo em conta dois agentes: o Estado e a família. A metodologia de pesquisa utilizada baseou-se na análise documental de âmbito qualitativo e quantitativo e a técnica de recolha de informação, em entrevistas de tipo semi-directivo, a dez casais, casados ou vivendo maritalmente, com filhos e que trabalham

Kansankirkko

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