606 resultados para 1091
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Incluye Bibliografía
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Incluye Bibliografía
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Camoens, the great Portuguese epic, was a Lucan’s reader, although it seems forgotten by some critics. Among the ancient writers who have influenced Camoens’ text, the Latin poet Lucan (AD 65) receives a smaller, but not irrelevant attention. This paper presents some allusions to Lucan in Os Lusíadas of Camoens, specially exploiting a long imitation of Pharsalia, II, 585-595.
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Angioinvasion/angiodestruction has been reported in a small subset of primary cutaneous anaplastic large-cell lymphomas (PCALCL). Recently, PCALCL with angioinvasive features and cytotoxic phenotype has been characterized as a variant associated with good clinical outcomes despite worrisome histopathologic features. We report a case of PCALCL with angioinvasive features and cytotoxic phenotype associated with reparative changes on the wall of medium-sized vessels involved by the neoplasm, including intimal fibroblastic proliferation and luminal obliteration. This vascular pattern, although previously unreported in PCALCL, is in accordance with the indolent behavior observed in this entity and provides a further link with lymphomatoid papulosis type E.
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Flavin mononucleotide (FMN) riboswitches are genetic elements, which in many bacteria control genes responsible for biosynthesis and/or transport of riboflavin (rib genes). Cytoplasmic riboflavin is rapidly and almost completely converted to FMN by flavokinases. When cytoplasmic levels of FMN are sufficient (high levels), FMN binding to FMN riboswitches leads to a reduction of rib gene expression. We report here that the protein RibR counteracts the FMN-induced turn-off activities of both FMN riboswitches in Bacillus subtilis, allowing rib gene expression even in the presence of high levels of FMN. The reason for this secondary metabolic control by RibR is to couple sulfur metabolism with riboflavin metabolism.
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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The Mr. USA Pageant Records consists of letters, news releases, newspaper clippings, memorabilia, and photographs relating to the operation of the pageant and the publicity generated from the pageant. The Mr. USA Pageant was held on May 13, 1977 in Charleston, SC as a spoof of traditional beauty pageants and was sponsored by the National Organization of Women (NOW).
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Bovine tuberculosis (TB) is a serious disease with animal health, public health, and international trade consequences. The cooperative Federal-State-industry effort to eradicate bovine TB from cattle in the United States has made significant progress since the program’s inception in 1917. However, the goal of eradication remains elusive. This proposed action plan presents Veterinary Services’ (VS’) current thinking about changes we are considering for the TB program to address our current challenges. This action plan will: 1. Reduce the introduction of TB into the U.S. national herd from imported animals and wildlife by: o Applying additional requirements to cattle imports from Mexico o Enhancing efforts to mitigate risks from wildlife 2. Enhance TB surveillance by: o Crafting a comprehensive national surveillance plan o Accelerating diagnostic test development to support surveillance 3. Increase options for managing TB-affected herds by: o Conducting epidemiological investigations and assessing individual herd risk o Applying whole-herd depopulation judiciously and developing alternative control strategies o Applying animal identification (ID) standards to meet animal ID needs 4. Modernize the regulatory framework to allow VS to focus resources where the disease exists 5. Transition the TB program from a State classification system to a science-based zoning approach to address disease risk To succeed, this new approach will require VS’ continued partnership with State animal health and wildlife officials, other Federal agencies, industry, international partners, academia, and other stakeholders. Successful partnerships will allow us to use available resources efficiently to achieve program objectives and protect our nation’s herd. Implementation of the VS proposed action plan will benefit Federal and State animal health officials, the regulated industries, and producers by allowing a more rapid response that employs up-to-date science and can adapt rapidly to changing situations.
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In the first seven months of 2008, eighteen Cuvier’s beaked whales (Ziphius cavirostris), four Sowerby’s beaked whales (Mesoplodon bidens), five unidentified beaked whales and twenty-nine long-finned pilot whales (Globicephala melas) were reported stranded in the UK and Ireland. Decomposition of those animals investigated puts the predicted time of death at mid-January. Concerns that an unusual mortality event had taken place prompted further investigations. Most carcasses were too decomposed for necropsy. A summary of findings is presented here. Although the initial stranding of five Cuvier’s beaked whales in Scotland shared some similarities with atypical mass stranding events linked in time and space to mid-frequency naval sonars, there were two important differences with the remaining strandings during this period. First, the geographical range of the event was very wide and second, the strandings occurred over a prolonged period of several months. Both of these factors could be related to the fact that the mortalities occurred offshore and the carcasses drifted ashore. The cause(s) of this high number of strandings of mixed offshore cetacean species during this period remain undetermined.
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The emergence of wavelength-division multiplexing (WDM) technology provides the capability for increasing the bandwidth of synchronous optical network (SONET) rings by grooming low-speed traffic streams onto different high-speed wavelength channels. Since the cost of SONET add–drop multiplexers (SADM) at each node dominates the total cost of these networks, how to assign the wavelength, groom the traffic, and bypass the traffic through the intermediate nodes has received a lot of attention from researchers recently. Moreover, the traffic pattern of the optical network changes from time to time. How to develop dynamic reconfiguration algorithms for traffic grooming is an important issue. In this paper, two cases (best fit and full fit) for handling reconfigurable SONET over WDM networks are proposed. For each approach, an integer linear programming model and heuristic algorithms (TS-1 and TS-2, based on the tabu search method) are given. The results demonstrate that the TS-1 algorithm can yield better solutions but has a greater running time than the greedy algorithm for the best fit case. For the full fit case, the tabu search heuristic yields competitive results compared with an earlier simulated annealing based method and it is more stable for the dynamic case.
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Lightpath scheduling is an important capability in next-generation wavelength-division multiplexing (WDM) optical networks to reserve resources in advance for a specified time period while provisioning end-to-end lightpaths. In this study, we propose an approach to support dynamic lightpath scheduling in such networks. To minimize blocking probability in a network that accommodates dynamic scheduled lightpath demands (DSLDs), resource allocation should be optimized in a dynamic manner. However, for the network users who desire deterministic services, resources must be reserved in advance and guaranteed for future use. These two objectives may be mutually incompatible. Therefore, we propose a two-phase dynamic lightpath scheduling approach to tackle this issue. The first phase is the deterministic lightpath scheduling phase. When a lightpath request arrives, the network control plane schedules a path with guaranteed resources so that the user can get a quick response with the deterministic lightpath schedule. The second phase is the lightpath re-optimization phase, in which the network control plane re-provisions some already scheduled lightpaths. Experimental results show that our proposed two-phase dynamic lightpath scheduling approach can greatly reduce WDM network blocking.